... synthase (iNOS) induced by interleukin-1β (IL-1β) in rat vascular smooth muscle cells (VSMCs). Western blot analysis demonstrated that IL-1β-induced iNOS expression was significantly reduced by hemin cotreatment or adenovirus-mediated HO-1 gene transfer. Scavenging carbon monoxide (CO), one...

... muscle cells. Cultured rat aortic smooth muscle cells were preincubated with E 2 , then stimulated with Ang II, and [ 3 H]thymidine incorporation and ET-1 gene expression were examined. The effect of E 2 on Ang-II-induced extracellular signal-regulated kinase (ERK) phosphorylation was tested to elucidate...

...Ming T. Lin; Wen-Chi Su; Mei-Ling Cheng; Kwang-Shien Cheng; Wen-Chang Chang; Lih-Yuh C. Wing; Chauyin J. Jen; Hua-Lin Wu The effects of fractionated oxidized low density lipoproteins (oxidized LDL) on the growth of vascular smooth muscle cells (VSMC) and their relationship to the formation...