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Keywords: Protein kinase c
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Journal of Biomedical Science (1994) 1 (4): 253–262.
Published Online: 11 August 2017
... as membrane protein kinase C (PKC) activity and the translocation of NADPH oxidase-cytosolic cofactor effected by priming levels of the two agonists. The investigation led to two important conclusions. First, we clearly demonstrate that priming by both SL-I and FMLP results from activation of cellular...
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Journal of Biomedical Science (1995) 2 (4): 357–365.
Published Online: 11 August 2017
... electrophysio- logical (whole-cell recording and single-channel recording), microspectrofluo- rimetric and biochemical techniques, we show that LSESr (1-30 μ/ml) reduced the basal activity of a K^+ channel and of protein kinase C (PKC) in CHO cells. In addition, pretreatment of the cells with 1-10 μ/ml LSESr...
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Journal of Biomedical Science (1995) 2 (3): 283–292.
Published Online: 11 August 2017
...Chuen-Mao Yang; Ming-Che Hsu; Richard Ong; Jen-Tsung Hsieh; Hui-Liang Tsao; Yi-Chin Chen; Shue-Fen Luo Regulation of the increases in inositol 1,4,5-trisphosphate (IP(3)) production and intracellular Ca^2+ concentration ([Ca^2+](i)) by activation of protein kinase C (PKC) was investigated...
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Journal of Biomedical Science (2004) 11 (6): 764–772.
Published Online: 01 December 2004
... inhibited thromboxane (Tx) A 2 formation stimulated by collagen. Moreover, ketamine (200 and 350 µ M ) increased the fluorescence of platelet membranes tagged with diphenylhexatriene. Rapid phosphorylation of a platelet protein of Mr 47,000 (P47), a marker of protein kinase C activation, was triggered...
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Journal of Biomedical Science (2004) 11 (6): 726–731.
Published Online: 01 December 2004
... or morphine were abolished by naloxone, a non-selective OR antagonist; nor-binaltorphimine, a selective ĸ-OR antagonist; naltrindole, a selective δ-OR antagonist, or CTOP, a selective µ-OR antagonist. The effects were also attenuated by blockade of protein kinase C or the mitochondrial K ATP channel...
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Journal of Biomedical Science (2003) 10 (2): 208–218.
Published Online: 28 February 2003
... phosphorylation in response to BK. BK-induced [ 3 H]thymidine incorporation and p42/p44 MAPK phosphorylation were inhibited by pretreatment of VSMCs with tyrosine kinase inhibitors (genistein and herbimycin A), protein kinase C (PKC) inhibitors (staurosporine, Go-6976, and Ro-318220), an MAPK kinase inhibitor...
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Journal of Biomedical Science (2001) 8 (6): 453–461.
Published Online: 15 November 2001
... Pharmacological Institute, College of Medicine, National Taiwan University, Taipei, Taiwan, ROC Key Words ·1-Adrenoceptor W Phenylephrine W Protein kinase C W Cardiomyopathic BIO 14.6 hamster Abstract Alterations in ·1-adrenoceptor (·1AR) density and related signal transduction proteins were reported...
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Journal of Biomedical Science (2001) 8 (1): 44–51.
Published Online: 19 January 2001
..., instructions or products referred to in the content or advertisements. Alcohol Adenylyl cyclase cAMP Protein kinase A Protein kinase C Review J Biomed Sci 2001;8:44 51 Phosphorylation Cascades Control the Actions of Ethanol on Cell cAMP Signalling Boris Tabakoff Eric Nelson Masami Yoshimura Kaisa...
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Journal of Biomedical Science (1999) 6 (4): 260–268.
Published Online: 16 July 1999
... of lysophosphatidylcholine (lyso-PC) as well as the activation of protein kinase C (PKC) were studied. VSMC were isolated from porcine aorta by explant culture. LDL was isolated from porcine blood by sequential ultracentrifugation and oxidized LDL was obtained by incubating LDL with 5 μ M CuSO 4 at 37°C for various lengths...
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Journal of Biomedical Science (1999) 6 (2): 97–105.
Published Online: 19 March 1999
... in PLD activity was inhibited by atropine (10 –6 M), indicating that activation of PLD occurred via muscarinic receptors. Activation of protein kinase C (PKC) by phorbol-12-myristate-13-acetate (PMA) increased PLD activity that was effectively blocked by the PKC inhibitors calphostin C (10 –8 to 10 –6 M...