...Patrick T. Donlon Neuroleptic agents by providing symptoms remission allow community physicians to treat the schizophrenic patient in all phases of the illness. The questions of the safety and efficacy of high dose neuroleptic therapy in subjects resistant to standard dose or requiring rapid...

...Thomas A. Ban Since maintenance therapy with neuroleptics, lithium and tricyclic antidepressants may have to continue over extended periods of time, drug interactions between these psychotherapeutic agents and non-psychotropic treatments have become of practical clinical significance. In this paper...

...Thomas A. Ban Adverse effects in maintenance therapy with neuroleptic drugs and lithium salts were reviewed with special emphasis on tardive dyskinesia. The possible teratogenicity of neuroleptics and lithium salts was discussed and the chromosomal abnormalities seen in patients treated...

.... 15: 281-291 (1980) A Controlled Trial of Oxypertine in Tardive Dyskinesia 1 H.L. Freeman, S.D. Soni, L. Carpenter Department of Psychiatry, University of Manchester School of Medicine, Hope Hospital, Salford, England 1608770 Key Words. Neuroleptics Oxypertine Tardive dyskinesia Double-blind...

...Joseph P. McEvoy; Stuart Bemey; William H. Wilson; Thomas A. Ban; William Guy Therapeutic and adverse effects of three dosages (1, 20 and 100 mg daily) of flutroline, a new 7-carboline with a predinical pharmacological profile similar to active neuroleptic agents, were compared in a double-blind...

...M. Ragheb The interaction of neuroleptics, tricyclic antidepressants, monoamine oxidase inhibitors, lithium and anxiolytic sedatives with other drugs and food is reviewed with special emphasis on drug interactions commonly encountered in psychiatric practice. Clinical relevance and mechanism...

...J. Kabeš; J. Pišvejc; L. Hanzliček; V. Skondia In a double-blind crossover placebo controlled trial the effectivity of piracetam in neuroleptic-induced extrapyramidal side effects was confirmed. 40 psychotic patients treated with neuroleptics in an average daily dose equal to 600 mg...

... that indicate Leonhard’s different subtypes of chronic schizophrenia may represent biologically distinct populations are presented. 11 8 2017 Chronic schizophrenia Neuroleptics Subtypes Treatment responsiveness Leonhard Classification 1608697 Int. Pharmacopsychiat. 17: 153-162 (1982...

...Rasmus Fog Bilateral microinjections of clozapine into the corpus striatum of rats antagonize amphetamine-induced stereotypy, and develops catalepsy. These two neuroleptic effects are not seen after subcutaneous or oral administration of clozapine. The effects were a little weaker than those seen...

...Paul J. Lewi The clinical and pharmacological activity spectra of the neuroleptics can be projected into a map where compounds with similar spectra, but with possibly different potencies, are grouped together. The spectral maps were devised for classification and for the prediction of therapeutic...

... plasma level. However, patients taking a combination of lithium and neuroleptic drugs had significantly higher lithium RBC/plasma ratios than patients taking lithium without neuroleptic drugs. The results are in line with earlier in vitro studies and are discussed in relation to the high frequency...

... monthly dose of 100 mg provided a suitable substitute for oral neuroleptic mono- and polytherapy and intramuscular fluphenazine decanoate. Stabilization or slight improvement was observed for all ten symptoms selected from the BPRS. The drug provoked a low incidence of side-effects allowing reduction...