...M. Mamelak Many features of manic-depressive illness can be mimicked in man by the use and withdrawal of amphetamines. In higher doses these drugs induce a syndrome virtually indistinguishable from paranoid schizophrenia. In this paper, some of the biochemical and physiological effects...

...Rasmus Fog Bilateral microinjections of clozapine into the corpus striatum of rats antagonize amphetamine-induced stereotypy, and develops catalepsy. These two neuroleptic effects are not seen after subcutaneous or oral administration of clozapine. The effects were a little weaker than those seen...