Some parts of the brain are not organized on the basis of ‘centers’where the different biological activities are analytically separated. It must be assumed that in some nervous structures the individuality of the different functions tends to disappear and to fuse into integrated patterns having a wide functional potentiality. Biological activities which take place in the more differentiated sections of the C.N.S. can be related each other when they attain a similar phase of non-specificity. From this point of view, in clinical psychiatry, we may consider the association and alternation of psychic and autonomic disorders in psychosomatic patients, the somatic and autonomic side effects of psychotropic drugs, the various EEGraphic pictures of confusional and comatose patients.

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1968
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