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Keywords: Woodchuck
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Journal Articles

Immunogenic Effects of Woodchuck Hepatitis Virus Surface Antigen Vaccine in Combination with Antiviral Therapy: Breaking of Humoral and Cellular Immune Tolerance in Chronic Woodchuck Hepatitis Virus Infection

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Stephan Menne, Carol A. Roneker, Bud C. Tennant, Brent E. Korba, John L. Gerin, Paul J. Cote
Journal: Intervirology
Intervirology (2003) 45 (4-6): 237–250.
https://doi.org/10.1159/000067914
Published Online: 30 January 2003
... in woodchucks chronically infected with the woodchuck hepatitis virus (WHV) by combining antiviral treatment with 1-(2-fluoro-5-methyl-β- L -arabinofuranosyl)-uracil (L-FMAU) and therapeutic vaccination with WHV surface antigen (WHsAg). Methods: Chronic WHV carriers were treated with L-FMAU or placebo for 32...
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Journal Articles

Evaluation of New Approaches to Prophylactic and Therapeutic Vaccinations against Hepatitis B Viruses in the Woodchuck Model

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Mengji Lu, Michael Roggendorf
Journal: Intervirology
Intervirology (2001) 44 (2-3): 124–131.
https://doi.org/10.1159/000050039
Published Online: 08 August 2001
...Mengji Lu; Michael Roggendorf The woodchuck model is most suitable for vaccine studies of prophylaxis and therapeutic treatment of hepatitis B virus infection. Recently, methodological advances allowed the examination of antigen-specific T cell responses in woodchucks during woodchuck hepatitis...
View article titled, Evaluation of New Approaches to Prophylactic and Therapeutic Vaccinations against Hepatitis B Viruses in the <span class="search-highlight">Woodchuck</span> Model
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