... circulated in the human population for about 80 years. In the infected patient, HIV mutates, and by elimination of some of the viruses by the action of the immune system individual quasispecies are formed. Along with the selection of the fittest viruses, mutation and recombination after superinfection...

...Hiroaki Okamoto; Shunji Mishiro There are four hierarchical strata in the genetic heterogeneity of hepatitis C virus (HCV): group above subgroup above isolates above quasispecies. The entire genome sequence has so far been reported for 16 isolates which are classifiable into 3 groups and 6...

...Hubert E. Blum Mutations of viral genomes are normal biological events and result in the coexistence of viral genotypes in infected individuals (‘quasispecies’). Hepatitis B virus (HBV) and the related animal hepadnaviruses have a mutation rate which is intermediate between DNA and RNA viruses...

... different heterogeneous mixtures defined as ‘quasispecies’, which vary in the hypervariable region 1 (HVR1) mostly. To further address the role of quasispecies diversity in hepatitis C infection, this study aimed to evaluate the influence of ALT, viral load and genotypes on quasispecies heterogeneity...