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Keywords: Oncogenic transformation
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Intervirology (2003) 46 (1): 1–16.
Published Online: 10 February 2003
... of oncogenic transformation, we point mutated the first splice donor in the Ad12-E1A gene, leading to the loss of the Ad12-E1A 9.5S and Ad12-E1A 11S/10S proteins and to a conservative amino acid (aa) exchange at position aa 30 (valine vs. leucine) in the Ad12-E1A 13S and Ad12-E1A 12S proteins. BMK cells...