...Wassim Chehadeh; Osama Albaksami; Sonia Elezebeth John; Widad Al-Nakib Objectives: Resistance-associated mutations (RAMs) in the integrase of different HIV-1 subtypes were investigated in a cohort of patients never exposed to integrase strand transfer inhibitors (INSTIs). Methods: The viral RNA...

... and HBsAg asymptomatic carriers among individuals infected with hepatitis B virus (HBV) with basal core promoter (BCP) double mutations (A1762T, G1764A). Methods: iTRAQ and liquid chromatography-tandem mass spectrometry were used to identify differentially expressed protein, and an ELISA test was used...

... polymerase transient expression system was employed to express the wild-type or mutated fusion (F) proteins. Three different types of membrane fusion assays were performed to analyze the fusogenic activity, fluorescence-activated cell sorting (FACS) analysis was executed to examine the cell surface...

... K, Cunningham SP, Trevino C, Davis C, Kennedy J, Fairman J, Foley B, Kop J: Sensitivity and specificity of the ViroSeq human immunodeficiency virus type 1 (HIV-1) genotyping system for detection of HIV-1 drug resistance mutations by use of an ABI PRISM 3100 genetic analyzer. J Clin Microbiol 2005;43...

... mutations in patients failing enfuvirtide. Methods: Collecting 476 and 135 HIV-1 B-subtype gp41 sequences from enfuvirtide-naïve and enfuvirtide-treated patients, respectively, two mutations previously found associated with enfuvirtide treatment, T18A and V38A, were analyzed. Moreover, the RNA secondary...

... and response to interferon and to put forward hypotheses to show the relationship of these mutations to the immune response. Their effects on overlapping regions are also discussed. Little is currently known about the functional importance of mutations within and around the X gene, but it is likely...

.... Polio RNA viruses DNA viruses Mutations Prions Introductory Lecture Intervirology 1993;35:9-15 Hilary Koprowski Thomas Jefferson University and Wistar Institute, Philadelphia, Pa., USA Yesterday, Today and Tomorrow in Virology Key Words Polio RNA viruses DNA viruses Mutations Prions Summary...

...Syed Naqui Kazim; Shiv Kumar Sarin; Barjesh Chander Sharma; Luqman Ahmad Khan; Seyed Ehtesham Hasnain Background: Besides vaccine escape or immune escape hepatitis B virus (HBV) mutants, naturally occurring and drug-induced mutations have been reported in the surface gene (S-gene) of HBV. Aim...

... to examine the pathogenesis of HCV infection in more detail. 16 9 2005 Chemokines Hepatitis C virus Mutations Pathogenesis Plasmid, inducible Protein-protein interactions Viral replication Yeast two-hybrid system Pathophysiology Intervirology 2006;49:44 50 DOI: 10.1159/000087262 Use...

...Yasushi Seo; Seitetsu Yoon; Miyuki Nakaji; Yoshihiko Yano; Hidenobu Nagano; Toshiaki Ninomiya; Yoshitake Hayashi; Masato Kasuga Objectives: We examined the level of hepatitis B virus (HBV) DNA and the mutations in the precore, core and polymerase regions of HBV in sera from anti-HBe-positive...