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Keywords: Human cytomegalovirus
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Intervirology (2017) 59 (5-6): 262–266.
Published Online: 13 April 2017
...Azam Mirarab; Alireza Mohebbi; Abdolvahab Moradi; Naeme Javid; Mohammad Ali Vakili; Alijan Tabarraei Objective: Drug-resistant isolates of human cytomegalovirus (HCMV) have led to the development of new anti-HCMV drugs. Maribavir (MBV) is a novel inhibitor of the HCMV viral kinase. Resistance...
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Intervirology (1996) 39 (5-6): 293–301.
Published Online: 30 July 2008
...John Sinclair; Patrick Sissons Human cytomegalovirus (HCMV), like all herpesviruses, persists in the host after primary infection, with reactivation often occurring as a result of immunosuppression. The lack of a model system has made analysis of HCMV latency and reactivation difficult. However...
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Intervirology (1996) 39 (5-6): 361–377.
Published Online: 30 July 2008
...Deborah H. Spector The multiple pathogenic effects of human cytomegalovirus (HCMV) result from a complex interplay of viral gene products and induced and repressed cellular functions. HCMV immediate early and early gene expression clearly play a pivotal role in this scheme. I describe here work...
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Intervirology (1997) 40 (5-6): 357–367.
Published Online: 30 July 2008
...Jens-Owe Vogel; Martin Scholz; Jindrich Cinatl, Jr. This review summarizes current strategies for the treatment of human cytomegalovirus (CMV) infection/diseases in high-risk patients such as transplant recipients and AIDS patients. Since the major drugs ganciclovir (Cytovene), foscarnet (Foscavir...
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Intervirology (1996) 39 (3): 204–212.
Published Online: 30 July 2008
...P. Schäfer; R. Laufs Human cytomegalovirus (HCMV) is a major pathogen in newborn children and immunosuppressed individuals. There are various diagnostic methods for HCMV, but all test systems either suffer from limited sensitivity and specificity or are prone to sampling errors. Due to its...
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Intervirology (1993) 35 (1-4): 60–72.
Published Online: 29 July 2008
..., the diagnostic methods for rapid and sensitive detection of symptomatic infection have been developed and recently refined. In human cytomegalovirus (HCMV), the use of recombinant viral antigens provides a rationale to improve serological assays. This may be of use for the discrimination of primary versus...
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Intervirology (1988) 29 (2): 101–107.
Published Online: 29 July 2008
...Klaus Radsak; Claus-Jürgen Kaiser; Dieter Haustein; Fred Rapp Two DNA-negative temperature-sensitive mutants of human cytomegalovirus strain AD 169 were shown to be deficient in induction of several prominent viral polypeptides when grown in human foreskin fibroblasts under nonpermissive conditions...
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Intervirology (1981) 16 (4): 233–243.
Published Online: 24 July 2008
...Janet D. Smith; Dorothy M. Moore L-Canavanine, a naturally occurring analog of arginine, effectively inhibited the morphogenesis of herpes simplex virus (HSV) and human cytomegalovirus (HCMV) when added at the time of infection, but allowed the expression of several cytopathic changes. Exposure...