... information about the distribution and diversity of herpesviruses in wild rodent and shrew species in central Africa, animals in Cameroon and the Democratic Republic of the Congo were sampled and tested by PCR for the presence of herpesvirus DNA. Methods: A broad range PCRs targeting either the Polymerase...

... of the herpesviruses which can exhibit chronic, latent infections. Reactivation of Epstein-Barr virus (EBV) has been reported to be involved in this chronic illness [2-4], Chronic active EBV infection may occur when reactivation coincides with impaired host responses [5]. In spite of the association of EBV...

...,UFCanAiirvc9eh4ris3lid0ty5S-Sc5ice4hn0oc2oel(BUoufSiMAld)eindgicine tory strain by at least 19 ORFs (UL133-UL151; Gene- to other herpesviruses whose genomes have been se­ Bank accession number U33331). The other popular labo­ quenced. Seventy-eight of the 170 ORFs encoded by ratory strain, Towne, also has a large deletion...

... and double-minutes but no dicentrics. These results suggest that CMVtransformed cells maintained an abnormal, but stable chromosome complement in vitro, but these became unstable when derived from tumors. Some marker chromosomes seemed stable. Human herpesviruses have recently been shown to transform Syrian...

... on the relatedness of herpesviruses through DNA-DNA hybridization. Virology 49: 95-101 (1972). 7 Josse, J.: Kaiser, A .D .. and Kornberg, A.: Enzymatic synthesis of deoxyribonucleic acid. VII, Frequencies of nearest neighbor base sequences in deoxyribonucleic acid. J. biol.Chem. 236: 864-875 (1961). 8 Schf.kman, R...

...T. Borcholte; V. Kliem; W. Verhagen; H.H. Wellhöner Herpesvirus type 1 could be propagated most efficiently in cultured fetal neurons, to a lesser extent in NG108–15 neurohybridoma cells, and with the lowest titer in glial cells. Herpesvirus type 2 could not be cultured in neurohybridoma cells...

... (1979). 6 Rabin, H.; Neubauer, R.H.; Hopkins, R.F. I ll; Nonoyama, M.: Further characterization of a her­ pesvirus-positive orangutan cell line and compar­ ative aspects of in vitro transformation with lym­ photropic Old World primate herpesviruses. Int. J. Cancer 27:762-767 (1978). 7 Heller, M.: Kieff...

... to be a herpesvirus. Of the known herpesviruses, only PsR virus contains DNA with a density of 1.731 g/cm3, that is similar to the high density DNA described here. However, high concentrations of anti-PsR serum failed to inhibit the synthesis o f high density DNA. In addition, antiserum to herpes­ virus cuniculi...

..., however, showed an enhanced reactivity which approached that seen with the tumor-derived cell lines. Mammalian cells in culture possess virus-specific antigens on plasma mem­ branes after productive infection by herpesviruses [1-3] or after transfor­ mation by UV-irradiated herpesviruses [4,5], In HSV...

.... L. and Rapp, F. : Induction of murine p30 by superinfecting herpesviruses. J. Virol. 19: 1028-1033(1976). 10 Y ang, S.S.; Ablashi, D.; Armstrong, G., and T ing, R.C.: RNA-dependcnt DNA polymerase associated with a simian lymphoid cell line derived from a Herpesvirus .«j/'m/n-induced lymphoma. Int. J...

...-Iymphotropic human herpesvirus, EBV, binds selectively to B lymphocytes and derived lines [8,9,24]. There is a close sterical association between the EBV receptor and the C3 receptor on human B cells [25,26], The nature of the T-cell receptor for the Tlymphotropic herpesviruses, HVA and HVS, remains...

... strategies employed by viruses has been the subject of several recent reviews [1 6]. For large DNA viruses, such as pox- and herpesviruses, examination of genomic sequences has revealed the presence of viral genes with striking homology to cellular genes with immunomodulatory functions. In this paper we...

... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Herpesvirus Viruses Disinfectant Original Paper Intervirology...