...Hua-Bing Liu; Qin-Yan Chen; Xue-Yan Wang; Lu-Juan Zhang; Li-Ping Hu; Tim J. Harrison; Chao Wang; Zhong-Liao Fang Background: Serum osteopontin (OPN) concentrations were found to be significantly increased in patients infected with hepatitis B virus (HBV) and patients with hepatocellular carcinoma...

... with reduced risk of disease progression. We aimed to assess the incidence of cirrhosis and hepatocellular carcinoma (HCC) and to identify risk factors associated with disease progression. Methods: We retrospectively reviewed 280 CHC patients who were registered at our hospital between 2001 and 2010. Results...

... in anti-HBe-negative cases. Table 2 Demographic data in with respect to the PC and BCP mutations in HBV among the nonvaccinated subjects PC Mutation Hepatitis B virus Basal core protein Precore gene Mutation Nicobarese Aboriginal Hepatocellular carcinoma Cirrhosis...

... Pasquale; Carmela Cacciapuoti Objective: Hepatitis C virus (HCV) has emerged as a leading cause of chronic hepatitis, liver cirrhosis and hepatocellular carcinoma worldwide. The purpose of this study was to describe the distribution pattern of HCV genotypes in chronic hepatitis patients in the Campania...

...Chao-Hung Hung; Chien-Hung Chen; Chuan-Mo Lee; Tsung-Hui Hu; Sheng-Nan Lu; Jing-Houng Wang; Chao-Min Huang Background/Aims: The independent and interactive effects of hepatitis B virus (HBV) and hepatitis C virus (HCV) factors on the development of hepatocellular carcinoma (HCC) in chronic HBV/HCV...

... variations were identified through direct DNA sequencing using TaqMan assay in 1,439 patients with past or present HBV infection. Subjects included 404 spontaneously recovered patients, 313 chronic hepatitis B (CHB) patients, 305 liver cirrhosis (LC) patients and 417 hepatocellular carcinoma (HCC) patients...

... from any ideas, methods, instructions or products referred to in the content or advertisements. Hepatitis C virus Interferon Ribavirin Hepatocellular carcinoma Cirrhosis Biochemical response Hepatitis C virus (HCV) usually causes chronic infection, which can result in chronic...

... (HCV) genotype 1b (HCV-1b) is an important predictor of hepatocellular carcinoma (HCC), but its impact on HCC in nonresponders to interferon (IFN) and ribavirin (RIB) combination therapy is not clear. Methods: A total of 292 patients with HCV-1b-related chronic liver disease who did not achieve...

...Myoung Ha Lee; Do Young Kim; Ja Kyung Kim; Hye Young Chang; Se Hun Kang; Han Jak Ryu; Hye-Lim Ju; Seung Up Kim; Jung Min Lee; Jun Yong Park; Kwang-Hyub Han; Chae Yoon Chon; Sang Hoon Ahn Background: The interactions among hepatitis B virus (HBV) mutations in developing hepatocellular carcinoma (HCC...

... Research Foundation, and f Japanese Red Cross Society Blood Service Headquarters, Tokyo, Japan Key Words Hepatitis C virus Hepatitis B virus Blood donors Liver cirrhosis Hepatocellular carcinoma Healthcare Japan curate estimation of undiagnosed HCV and HBV carriers in the general population...

...Yu Zhu; Yan Jin; Xiaojin Cai; Xin Bai; Min Chen; Taoyang Chen; Jinbing Wang; Gengsun Qian; Jianren Gu; Jinjun Li; Hong Tu Objectives: To characterize the mutation pattern of a hepatitis B virus (HBV) core protein (HBcAg) derived from hepatocellular carcinoma (HCC) and adjacent nontumor tissues...

...Hobyung Chung; Taisuke Ueda; Masatoshi Kudo In Japan, hepatocellular carcinoma (HCC) is the fourth leading cause of death in males and the fifth in females. Hepatitis C virus (HCV) is a major cause of HCC in Japan, with 70% of cases being HCV related. HCV genotype 1b, the most prevalent subtype...

... Intervirology 2010;53:111 118 DOI: 10.1159/000264201 Received: August 14, 2009 Accepted after revision: October 12, 2009 Published online: December 3, 2009 Impact of Serial Hepatitis B Virus DNA on Hepatocellular Carcinoma Development in Patients with Liver Cirrhosis Jung Hyun Kwon Jong Young Choi Jeong Won...

... of the hemodynamics of hepatic lesions. Contrast-enhanced ultrasonography Dynamic computed tomography Focal hepatic lesions, hemodynamics Hepatic lesions ≤20 mm, hemodynamic status Hepatocellular carcinoma Kupffer imaging Sonazoid Time intensity curve Ultrasonography 18 02 2009 15 05 2009...

... compared the characteristics and survival of 92 elderly (≥75 years) patients with HCV-related hepatocellular carcinoma (HCC) (including 62 patients with HCV-1b) with those of 44 younger patients (<50 years, 34 patients with HCV-1b). Results: For all patients, univariate analysis identified female sex...

... the distribution of hepatitis C virus (HCV) genotype and the possible association between genotype and HCV-associated liver disease in Indonesia. Methods: 32 anti-HCV-positive asymptomatic carriers (AC), 55 chronic hepatitis (CH), 41 liver cirrhosis (LC), and 35 hepatocellular carcinoma (HCC) patients were...

... identified total bilirubin, AST, and nt substitutions (nt 1762, 1768, 1846, 1896, 2134, 2288, 2441) as determinants of early non-detectable HBV-DNA. The yearly incidence of hepatocellular carcinoma (HCC) during the first 3 years was 2.7%. At the diagnosis of HCC, ALT normalization, HBV-DNA non-detectable...

... patients in terms of their clinical profiles. For HBV DNA-positive patients, the degree of inflammatory cell infiltration and irregular regeneration of hepatocytes was significantly greater than for HBV DNA-negative patients. The cumulative probability of development of hepatocellular carcinoma (HCC...

... ablation (RFA) therapy for hepatocellular carcinoma. The aim of this study was to investigate how liver tissue could be disseminated during the RFA procedure with different devices and protocols in an in vivo porcine model. Methods: Three pigs underwent RFA procedures using 2 different devices: needles...

... hepatitis C (68%) it develops into chronic hepatitis. Once chronic hepatitis is established, the rate of spontaneous cure of the liver disease is very rare (below 2%). The duration from the onset of acute hepatitis until the time of diagnosis of cirrhosis of the liver and of hepatocellular carcinoma...