... in catabolic and anabolic processes within the infected cells. Methods: Huh7 liver cells in culture were infected with hepatitis C virus (HCV). We performed proteomics analysis of key proteins in infected cells by Western blotting and IP experiments, with or without IFNα exposure as a component of conventional...

...Tshegofatso K. Maunye; Maemu P. Gededzha; Jason T. Blackard; Johnny N. Rakgole; Selokela G. Selabe Introduction: Hepatitis C virus (HCV) genotype 5 was originally identified in South Africa, where it represents 35–60% of all HCV infections. There are limited data on resistance-associated variants...

...Huanqin Li; Shumin Liu; Yun Lin; Xiongfei Shi; Na Du; Jing Yao; Ruiyang Liu; Yan Du; Kai Yang Introduction: Accumulated studies have suggested that hepatitis C virus (HCV) infection is one of the leading causes for hepatocellular carcinoma (HCC). However, the mechanisms underlying the effect of HCV...

... Simpore Introduction: Hepatitis C virus (HCV) infection remains a major public health problem worldwide. In Burkina Faso, nearly 720,000 people are living with HCV, and each year about 900 people die from complications of cirrhosis or hepatocellular carcinoma. This study was planned to determine the HCV...

...Ali Akhtar; Samreen Fatima; Hamid Saeed; Chow Ting Soo; Amer Hayat Khan Background: Around 130 million infections of hepatitis C virus with 3% overall prevalence are there worldwide. There are approximately 4–5 million persons coinfected with HIV. The main objectives of this study were to determine...

...Kazuhiko Hayashi; Kosuke Tachi; Yuko Shimizu; Kenichi Nagano; Yoji Ishizu; Teiji Kuzuya; Takashi Honda; Masatoshi Ishigami; Yoshiki Hirooka; Masashi Hattori; Hidemi Goto Background: The incidence of mixed hepatitis C virus (HCV) genotype infection is variable, and a few reports exist regarding...

...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. RNA interference Hepatitis C virus siRNA shRNA Lentiviral vector La autoantigen NS5B In recent years...

...Deborah D’Aliberti; Irene Cacciola; Cristina Musolino; Giuseppina Raffa; Roberto Filomia; Angela Alibrandi; Salvatore Benfatto; Concetta Beninati; Carlo Saitta; Domenico Giosa; Orazio Romeo; Giovanni Raimondo; Teresa Pollicino Background: Hepatitis C virus (HCV) NS3 resistance-associated...

...Elena Grimaldi; Maria Elena Della Pepa; Francesca Martora; Pasqualino Magliocca; Maria Rosaria Iovene; Nicola Coppola; Giovanna Donnarumma; Massimiliano Galdiero Aims: The objective of this work was to study the distribution of hepatitis C virus (HCV) genotypes and subtypes from 2010 to 2015...

... 2007 and January 2016. Acute viral infections were observed in 23 (19.8%) patients with HEV, 49 (42.2%) patients with hepatitis A virus, 28 (24.1%) patients with hepatitis B virus, and 16 (13.8%) patients with hepatitis C virus. Results: The incidence of acute HEV infection was higher among older...

... to in the content or advertisements. Ribavirin Antiviral therapy Hepatitis C virus Interferon-α-2b Sustained virological response Viral load Hepatitis C virus (HCV) is a major cause of liver-associated diseases throughout the world. Approximately 3% of the world's population is chronically...

...Hong Lin; Xian Chen; Shaowen Zhu; Ping Mao; Shanshan Zhu; Yanchun Liu; Chengyin Huang; Jun Sun; Jin Zhu Objective: In 2010, only 1 donor blood sample was found to be anti-hepatitis C virus (HCV) negative and HCV RNA positive, as detected by nucleic acid testing. In occult HCV infection (OCI), HCV...

...Vo Duy Thong; Kittiyod Poovorawan; Pisit Tangkijvanich; Rujipat Wasitthankasem; Sompong Vongpunsawad; Yong Poovorawan Objectives: We conducted a systematic review and meta-analysis of the influence of host and viral factors on the sustained virologic response (SVR) in hepatitis C virus genotype 6...

...Mohamed Abdel-Fattah; Ragia Charmy; Abdel-Rahman Tawfik We have studied the immune reactivity of hypervariable region 1 (HVR1) of hepatitis C virus (HCV) against HCV immune positive and negative sera. Two published HVR1 consensus nucleotide sequences (Italian and Chinese) were synthesized...

... or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Hepatitis C virus Chronic...

...Sarah Aherfi; Olga Glazunova; Patrick Borentain; Daniele Botta-Fridlund; Laurent Chiche; Sylvie Bregigeon; Anne Motte; Catherine Tamalet; Philippe Colson The rate of eradication of chronic hepatitis C considerably increases with direct-acting antiviral agents, particularly hepatitis C virus (HCV...

...Nghia H. Nguyen; Shelley A. McCormack; Philip Vutien; Brittany E. Yee; Pardha Devaki; David Jencks; Mindie H. Nguyen Objective: Our goal was to systematically and quantitatively assess treatment response between Asian patients with hepatitis C virus genotype 6 (HCV-6) and hepatitis C virus genotype...

...Izuru Ando; Naoki Ogura; Yukiyo Toyonaga; Kunihiro Hirahara; Tsutomu Shibata; Toru Noguchi JTK-853 is a novel, non-nucleoside, palm site-binding hepatitis C virus (HCV) polymerase inhibitor that has demonstrated antiviral activity in HCV-infected patients during 3 days of treatment. To estimate...

... advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. The hepatitis C virus (HCV) is distributed...

...Chao-Hung Hung; Tsung-Hui Hu; Chuan-Mo Lee; Chao-Min Huang; Chien-Hung Chen; Jing-Houng Wang; Sheng-Nan Lu Background/Aims: Hepatitis C virus (HCV) core protein can induce liver steatosis and glucose intolerance in transgenic mice. We aimed to clarify the association of HCV core region...