...Erik Nordenfelt; Lars Kjellén Two different categories of hepatitis B antigen carriers have been investigated. One comprises patients treated with dialysis and known to be highly infectious. The other consists of blood donors found in routine screenings. Serum specimens have been studied...

..., Md. Key Words. Hemolytic plaque assay Hepatitis B antigen Summary. Hemolytic plaque assays in gel were performed against burro red blood cells (BRBC) conjugated with hepatitis B surface antigen (HBS Ag). On indirect assay, spleen cells from HBS Ag-immunized mice gave 27-68 times more plaques than...

...Colin R. Howard; Arie J. Zuckerman The close association of hepatitis B antigen with serum proteins was demonstrated. The small morphological form of the antigen, measuring approximately 20 nm in diameter, was separated by isoelectric focusing and the heterogeneity of the antigen was confirmed...

...Ruben Chairez; Blaine Hollinger; Joseph L. Melnick; Gordon R. Dreesman The morphological forms of hepatitis B antigen (HBsAg) present in an HBsAg-positive plasma (15–25 nm spheres, filaments 20–22 nm in diameter and 80–300 nm in length, and 42 nm Dane particles) were isolated and characterized...

...Ruben Chairez; Sheldon Steiner; Joseph L. Melnick; Gordon R. Dreesman The total carbohydrate content of purified hepatitis B antigen (HB Ag) ranged between 3.6 and 6.5% as determined by the phenol-sulfuric acid method. Disc-sodium dodecyl sulfate PAGE of purified HB Ag followed by periodate-Schiff...

...George L. Le Bouvier; William H. Bancroft; Paul V. Holland We describe an example of the rare, recently identified ayr phenotype of hepatitis B antigen, detected in the serum of a carrier in New Guinea. All three determinants were apparently present together on the same antigenic particle...

...Erik Nordenfelt; George Le Bouvier A patient carrying hepatitis B antigen with both d and y specificities on the same particles (diplotypic HB Ag) has been followed over a period of two years, with examination of repeated blood samples.Titration studies on these sera consistently showed a stronger...