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Keywords: Error catastrophe
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Journal Articles
Subject Area:
Further Areas
Keiko Arataki, Hiromitsu Kumada, Kiyomi Toyota, Waka Ohishi, Shoichi Takahashi, Susumu Tazuma, Kazuaki Chayama
Journal:
Intervirology
Intervirology (2006) 49 (6): 352–361.
Published Online: 06 October 2006
... that ribavirin induces nucleotide substitutions in the viral genome and reduces viral load by forcing it into error catastrophe in the combination therapy, we investigated the molecular evolution of HCV quasispecies in 3 patients who received combination therapy and 2 patients who received interferon monotherapy...