...Patricia N. Fultz; Harold M. McClure; Brent Swenson; Daniel C. Anderson Following inoculation of chimpanzees, the human immunodeficiency virus (HIV) establishes a long-term persistent infection characterized by seroconversion and the presence in peripheral blood cells of recoverable virus which can...

...Bert L. Murphy; James E. Maynard; George L. Le Bouvier Chimpanzees were inoculated with human plasmas of known infectivity containing hepatitis B surface antigen (HBS Ag) of both d and y subspecificities in an attempt to examine the subspecificity characteristics of chimpanzee antibody responses...

...Narayan C. Khan; Blaine Hollinger; Joseph L. Melnick The localization of hepatitis A virus antigen to specific subcellular fractions of infected chimpanzee liver cells was studied by solid-phase radioimmunoassay following a mild subcellular fractionation procedure designed to separate various...

...Cecil L. Hornbeck; Clifton R. Gravelle; Blaine Hollinger; Daniel W. Bradley Virus-like particles shown to be associated with hepatitis A infection were recently visualized by immune electron microscopy in human and chimpanzee acute-phase fecal extracts. Agarose gel filtration of concentrated...

...Bert L. Murphy; John M. Peterson; James W. Ebert; Kenneth R. Berquist; James E. Maynard; Robert H. Purcell Three chimpanzee chronic carriers of hepatitis B surface antigen (HBS Ag) were examined by immunofluorescent techniques to determine the localization of HBS Ag and hepatitis B core antigen...

...Blaine Hollinger; Gary L. Gitnick; Richard D. Aach; Wolf Szmuness; James W. Mosley; Cladd E. Stevens; Robert L. Peters; John M. Weiner; Jochewed B. Werch; Jerrold J. Lander Experimental transmission of non-A, non-B hepatitis was apparently accomplished in 5 chimpanzees following inoculation...

... on existing vaccines could be beneficial, especially in situations where it is desirable or necessary to induce protective immunity more rapidly or with fewer doses. We have compared, in chimpanzees, a current HBV vaccine that contains recombinant hepatitis B surface antigen HBsAg) adsorbed to alum, with two...

...Junko Tanaka; Keiko Katayama; Junko Kumagai; Yutaka Komiya; Hisao Yugi; Shinya Kishimoto; Masaaki Mizui; Tetsushi Tomoguri; Yuzo Miyakawa; Hiroshi Yoshizawa Two chimpanzees were inoculated with hepatitis C virus (HCV) and followed on a daily basis for 12 days. HCV RNA became detectable...