... protein response (UPR) and subsequent activation of apoptosis. Results and Conclusions: Following transfection with D3, HBeAg passed through the secretory pathway earlier than cells transfected with genotype A. Cells transfected with A1 showed a lower expression of the preC/C precursor in the secretory...

... were compared between the CHIKV-infected C6/36 and Vero cells. Apoptosis was measured by TUNEL assay, and the differences between the C6/36 and Vero cells were compared. Results: CHIKV infection induced strong CPE and apoptosis in the Vero cells, but light CPE in the C6/36 cells. The virus titers...

... protein of chicken infectious anemia virus, is a p53-independent, Bcl-2-insensitive apoptotic protein with the ability to specifically induce apoptosis in transformed cells. In this study, we tested the hypothesis that apoptin enhances NDV-mediated tumor cell death. Methods: Reverse genetics was used...

...Aidin Molouki; Yi-Te Hsu; Fatemeh Jahanshiri; Rozita Rosli; Khatijah Yusoff Background/Aims: Newcastle disease virus (NDV) is an avian paramyxovirus that has gained a lot of interest in cancer viro-therapeutic applications because of its ability to selectively induce apoptosis in human cancer cells...

...Noboru Uchide; Kunio Ohyama; Toshio Bessho; Hiroo Toyoda Objective: In order to elucidate the implication of apoptosis in lactate dehydrogenase (LDH) leakage from influenza virus-infected cells, the effects of a general caspase inhibitor, N - t -Boc-Asp(OMe)-fluoromethylketone (Boc-D-fmk), on LDH...

...Chan-Yen Kuo; Jing-Chyi Wang; Shih-Lan Hsu; Guang-Yuh Hwang Objective: This study aimed to determine the effects of HBx on the inhibition of tumorigenesis in nude mice injected with CCL13-HBx cells. Therefore, the characteristics of the induced tumors and the phenomenon of apoptosis were assessed...

... carcinoma DNA-binding sites Oral hairy leukoplakia Apoptosis Cancer EBV Intervirology 1995:38:195-205 D. Horner M. Lewis P.J. Farrell Ludwig Institute for Cancer Research, St. Mary s Hospital Medical School, London, UK Novel Hypotheses for the Roles of EBNA-1 and BHRF1 in EBV-Related Cancers Key...

... involved in apoptosis of these cells are discussed in relation to HTLV-I infection. 30 7 2008 © 1995 S. Karger AG, Basel 1995 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized...

... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Apoptosis Cassel’s 73-T NDV strain Cytokines Genetically engineered virus Lymphokines Oncolytic virus Postoncolytic immunity Viral oncolysate Review Intervirology...

... by performing semiquantitative RT-PCR and Western blotting. Furthermore, the phenomenon of cell death via apoptosis was detected via DNA fragmentation, TUNEL staining, caspase-3 activity assay, and propidium iodide (PI) staining. Results: The results indicated that HBx induction downregulated Wnt-3 and β...

...-15 cells by liposome, and positive cell clones were gained by G418. The NS3-EGFP fusion protein expressed in pEGFP-C1-NS3 cells was observed by inverted fluorescence microscopy and identified by Western blot. The CPE appeared in positive pEGFP-C1-NS3 cells 72 h after passaging, apoptosis detection...

...Lin Zheng; Yida Yang; Lu Guocai; C. David Pauza; Maria S. Salvato Objective: To investigate the effect of HIV Tat protein on Bcl-2 expression in human monocytes, and observe apoptosis of Tat-stimulated monocytes induced by TNF-α-related apoptosis-induced ligand (TRAIL). Methods: Western blot...

...Noboru Uchide; Kunio Ohyama; Toshio Bessho; Hiroo Toyoda Objectives: We investigated the involvement of p38 mitogen-activated protein (MAP) kinase in tumor necrosis factor (TNF)-α gene expression, apoptosis induction and virus replication in cultured human fetal membrane chorion cells infected...

...S.-O. Chen; T.-J. Chang; G. Stone; C.-H. Chen; J.-J. Liu Objective: The Japanese encephalitis virus YL vaccine strain (JEV-YL) was investigated as regards its organ tropism and the role of recombinant envelope glycoprotein in the induction of apoptosis was explored. Methods: Threevaried cell lines...

...Roberto G. Pozner; Maria I. Berría; Soledad Negrotto; Mirta Schattner; Ricardo M. Gómez Objectives: We aimed to address if selective astrocyte apoptosis is involved in the lack of murine demyelinating disease following infection by the L*-1 variant of Theiler’s virus. In addition, we investigated...

... injury in the infected organs. We examined effects of an antioxidant, nordihydroguaiaretic acid (NDGA), on apoptosis induction and viral proliferation. Subsequently, the results were compared with those of pyrrolidine dithiocarbamate (PDTC), another antioxidant. Methods: The levels of ROS production were...

..., instructions or products referred to in the content or advertisements. Large liver cell dysplasia Hepatitis B virus HBX transgenic mouse Proliferation Apoptosis Intervirology 2005;48:16 22 DOI: 10.1159/000082090 Large Liver Cell Dysplasia in Hepatitis B Virus X Transgenic Mouse Liver and Human...

... of the human papillomavirus type 16 (HPV-16) E5 protein on apoptosis. In comparison to conventional monolayer cultures this model system allows analysis of apoptosis under more tissue-like conditions by mimicking the stratified organization of a normal surface epithelium. Apoptosis was triggered either by FasL...

.... Orthomyxovirus Persistent infection Telomerase Apoptosis Nucleoprotein Original Paper Intervirology 2003;46:319 322 DOI: 10.1159/000073211 Received: April 15, 2003 Accepted after revision: July 16, 2003 Characterization of HeLa Cells Persistently Infected with Influenza Virus B/Lee/40 with Respect...

... of apoptosis, heavily condensed nuclei and subsequent chromatin condensation into the periphery of the nuclei within 12 h p.i. Moreover, we noticed typical oligonucleosomal DNA fragmentation, while productive CVB multiplication was accomplished within 6 h p.i. prior to an apoptotic signal. Caspase inhibitor...