Using two different techniques (an original RAST-like radio-immunoassay and indirect immunofluorescence) serum IgE anti-Brucella antibodies were detected in 59% brucellosis patients (76% in early samples from acute brucellosis) and in 43% subjects vaccinated with a phenol-insoluble Brucella fraction. IgE anti-Brucella antibodies are shown to appear after IgM but before IgG anti-Brucella antibodies in the course of the anti-Brucella response. There is no correlation between the presence of IgE anti-Brucella antibodies and the severity of brucellosis or its clinical manifestations. On the other hand, a significant association has been evidenced between the presence of mild reactions to primary vaccination and that of IgE antibodies induced by this vaccination. These findings are discussed in terms of their possible functional significance.

This content is only available via PDF.
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
You do not currently have access to this content.