... of their action. Tumor necrosis factor-α (TNFα) is actively involved in inflammation processes in atopic dermatitis (AD), but the role of TNFα membrane receptors (TNFR) and their regulatory function in AD remains unclear. Aim: We aimed to determine the associations of parameters of TNFRα expression...

..., instructions or products referred to in the content or advertisements. Biologicals Tumor necrosis factor CC chemokine receptor Granulocyte-macrophage colony-stimulating factor Chemoattractant receptor-homologous molecule expressed on T H 2 cells Macrolides Asthma Interleukins Treatment...

..., Simonini G, Nencini F, Liotta F, Romagnani S, Maggi E, et al: Brief report: etanercept inhibits the tumor necrosis factor α-driven shift of Th17 lymphocytes toward a nonclassic Th1 phenotype in juvenile idiopathic arthritis. Arthritis Rheumatol 2014;66:1372-1377. 41. O'Shea JJ, Paul WE: Mechanisms...

... exposure to antigen. Results: AHR increased at 10–12 h after airway challenge, followed by the second-phase response, which was larger and broader in resistance at 18–30 h. Pretreatment of sensitized animals with anti-tumor necrosis factor (TNF) before airway challenge or induction of allergic asthma...

... leukemic cells [ 12 ]. Our previous study also demonstrated that P-selectin immobilized on a culture plate effectively induced monocytes to secrete tumor necrosis factor (TNF)-α [ 13 ]. Cytokines secreted from monocytes have been shown to regulate various types of immune responses and inflammatory/allergic...

... microenvironment. Mast cells are critical for allergic, immune and inflammatory processes, many of which involve tumor necrosis factor (TNF). These cells uniquely store TNF in their secretory granules. Upon stimulation, mast cells rapidly (30 min) secrete β-hexosaminidase and granule-stored TNF through...

... of isomaltitol and Sephadex. After 24 h, the lungs were weighed to measure edema and preserved for histology. Bronchoalveolar lavage fluid was used for analysis of tumor necrosis factor, cysteinyl leukotrienes, and differential and total leukocyte counts. Results: Differential counts showed that isomaltitol...

...Ken’ichi Imanishi; Hidenobu Akatsuka; Katsuya Inada; Takehiko Uchiyama In the presence of IFN-γ-stimulated vascular endothelial cells which have acquired HLA class II molecules, T cells produced tumor necrosis factors (TNF-α and TNF-β) and IL-2 in response to stimulation with streptococcal...

... (PMNs, neutrophils) expressed ICAM-1 on their surface, and it was upregulated by in vitro stimulation with tumor necrosis factor (TNF), GM-CSF and Staphylococcus aureus . The S. aureus -induced stimulation of ICAM-1 expression was inhibited by pentoxifylline (PTX). As TNF is a potent inducer of ICAM-1...

...J.C. Kips; J.H. Tavernier; R.A. Peleman; G.F. Joos; R.A. Pauwels We have previously reported that exposure to aerosolized endotoxin causes bronchial hyperresponsiveness in rats. This is at least partly due to secondary release of tumor necrosis factor (TNF). In this study, we evaluated the effect...

...Judith K. Manning; Miroslav Malkovsky; Anthony Meager IL-3-dependent, murine mast cell lines derived from embryonic yolk sac precursors display a tumoricidal activity that is blocked by antibodies against tumor necrosis factor-α, indicating that this cytokine is the major mediator involved...

... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Lepra reaction IgG subclasses Cytokines Interferon-=γ Tumor necrosis factor Thalidomide Leprosy is a chronic infectious disease caused by Mycobacterium leprae which...

...: In this study, we examined the ability of a number of cytokines to suppress the activation of eosinophils that function as effector cells for allergic airway diseases. Results: Interleukin (IL)-5, IL-6, and tumor necrosis factor (TNF) induced an eosinophil shape change, whereas interferon (IFN)-γ significantly...

... II Fcε receptor (high-affinity IgE receptor) Tumor necrosis factor T cell receptor Genetic polymorphism Atopy is a genetic predisposition to respond to environmental allergens with significant amounts of specific IgE antibodies. It is associated with different symptomatologies ranging...

..., with or without addition of tumor necrosis factor (TNF), in a humidified atmosphere of 5% CO 2 /95% air at 37°C. Results: (1) While a higher amount of C3 was detected in medium when KATO–III cells were cultured in the presence of TNF than in medium lacking TNF, higher C2 activity was detected when cultured...

...: Immunostaining, RT-PCR, ELISA, immunoblot and Northern blot analyses were employed to study four murine MC lines for FGF-2 expression and its regulation by transforming growth factor-β (TGF-β), stem cell factor (SCF), and tumor necrosis factor-α (TNF-α). Results: Mouse tissue MC and three of four murine MC lines...