... of Life Questionnaire (AE-QoL). Results: Lanadelumab led to reductions of 97.8% and 98.5% in the attack rate and treated attack rate, respectively. All patients exhibited significant improvements in AE-QoL and DLQI scores (100% reduction rates) during the early treatment period (4 weeks and 2 weeks...

...Sinem Ornek Ozdemir; Pelin Kuteyla Can; Ece Nur Degirmentepe; Kübra Kızıltaç; Ralfi Singer; Emek Kocatürk Introduction: Chronic inducible urticaria (CIndU) is a subtype of chronic urticaria (CU), which requires specific triggers to occur. Despite their common occurrence, treatment response rates...

... during anaphylaxis was documented in 6 patients. Activating KIT p.D816V variant was detected in 2 patients. One patient also had hereditary alpha-tryptasemia (HαT). The duration of omalizumab treatment was 0.5–7.5 years. None of the patients have experienced an anaphylactic reaction since the start...

...Julie Holst Gudichsen; Emil Aggerholm Bækdal; Søren Mikkelsen; Annmarie Touborg Lassen; Frederik Bloch Jessen; Carsten Bindslev-Jensen; Charlotte G. Mortz Introduction: Although intramuscular adrenaline is the recommended first-line treatment for anaphylaxis, not all patients receive this treatment...

... and treatment of OD in patients are critical. Many etiological factors are responsible for OD based on current opinions. Sniffin’Sticks are recommended to identify the initial position (central or peripheral) for OD when treating patients clinically. It is worth emphasizing that the olfactory region in nasal...

...Emilio José Narváez-Fernández; Ana Entrala; Ana Nin-Valencia; Patricia Mir-Ihara; Itsaso Losantos-García; Javier Domínguez-Ortega; María Ángeles González-Fernández; Santiago Quirce; Natalia Hernández-Cano; Rosario Cabañas; Teresa Caballero Background: Biologics have revolutionized the treatment...

...Lin Lin; Jing Lan; Fei Dai; Jinjin Wei; Zheng Chen; Guangbin Sun Background: Neutrophilic chronic rhinosinusitis with nasal polyps (CRSwNP) occur predominantly in Asian subjects. Appropriate treatments for this endotype have not been elucidated. This study aimed to evaluate the efficacy...

...; Martin Metz This update on chronic urticaria (CU) focuses on the prevalence and pathogenesis of chronic spontaneous urticaria (CSU), the expanding spectrum of patient-reported outcome measures (PROMs) for assessing CU disease activity, impact, and control, as well as future treatment options for CU...

... be an attractive candidate target for asthma treatment. The lung tissues were fixed in 4% paraformaldehyde, embedded in paraffin, sectioned, and stained with hematoxylin and eosin to examine lung inflammation, or Periodic Acid-Schiff to observe hyperplasia and mucus secretion of airway mucosa goblet cells...

...Emek Kocatürk; Gustavo Deza; Kübra Kızıltaç; Ana M. Giménez-Arnau The recommended dose of omalizumab for the treatment of chronic spontaneous urticaria (CSU) is 300 mg every 4 weeks, but there is no recommendation for patients who do not benefit from this dose. Our aim is to present the experiences...

...Alper Yenigun; Ahmet Elbay; Remzi Dogan; Orhan Ozturan; Mehmet Hakan Ozdemir Objective: The aim of this study is to demonstrate the effect of nasal steroid treatment on intraocular pressure and dry eye in allergic rhinitis patients with dry eye. Materials and Methods: Twenty-nine patients...

...-Nunes; Dirceu Solé Background: Current guidelines on chronic spontaneous urticaria (CSU) suggest a treatment based on a 3-step approach that aims at total symptom control, starting with H1-antihistamines. However, a significant number of patients present an antihistamine-resistant urticaria that must...

... asthma phenotypes have opened up new therapeutic avenues for asthma treatment. The approval of the humanized anti-IgE antibody omalizumab for the treatment of severe allergic asthma has paved the way for other cytokine-targeting therapies, particularly those targeting interleukin (IL)-4, IL-5, IL-9, IL...

...Timothy J. Craig; Jonathan A. Bernstein; Henriette Farkas; Laurence Bouillet; Isabelle Boccon-Gibod Several types of angioedema exist beyond hereditary angioedema (HAE) types I/II; however, the diagnostic and treatment needs of these conditions are not well understood. Noticeably...

... to allergic rhinitis (AR) treatment is limited at present. We aimed to assess whether a daily SMS reminder could improve AR patients' adherence to medication and treatment outcomes. Methods: Fifty outpatients with AR were randomized to either receive (SMS group) or not (control group) a daily SMS reminder...

... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Fexofenadine HCl Chronic idiopathic urticaria Japanese patient Antihistamine Treatment Fexofenadine is a nonsedating antihistamine...

... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Asthma Education Intervention Morbidity Treatment Peter J. Gergen Robert A. Goldstein N1AID-NIH, Bethesda, Md., USA Pathogenesis and Management Int Arch Allergy Immunol 1995;107...

... corticosteroid treatment can ameliorate this inflammation. In addition, even a morphologically normal epithelial structure may be restored. However, factors which may lead to more chronic disease have remained obscure. Recent studies are now focusing on the reversibility of collagen deposition in the airway...

...Winfried Graninger; Josef Smolen Chimeric, humanized and fully human monoclonal antibodies directed against tumor necrosis factor-α as well as TNF receptor constructs can be administered relatively safely during long-term use for the treatment of rheumatoid arthritis (RA). Their therapeutic...