... correlated with methacholine dose producing a decrease of 20% from baseline in forced expiratory volume in the first second (PD20) in CD4 + T cells of asthma. Furthermore, hsa_circ_0002594 expression was higher in subgroups with a family history, skin pricking test (SPT)-positive, or Th2-high...

... to obtain a precise D. pteronyssinus molecular diagnosis in asthmatics with a climate-dependent high-mite allergen exposure and coexisting sensitization. A dominant role of both major and mid-tier allergens has been confirmed in moderate and severe persistent asthmatics with the preponderant Th2-high...

... helper (Th2) immune response is responsible for the pathogenesis of allergic asthma. To suppress the enhanced Th2 immune response, activation of the Th1 immune response has been an alternative strategy for anti-asthma therapy. In this context, effective Th1-inducing adjuvants that inhibit the development...

... DNCB-induced IgE and Th2 cytokines in the peripheral blood. At the skin lesion site, verbascoside also inhibited DNCB-induced production of proinflammatory cytokine TNF-α, IL-6, and IL-4 mRNA. In a human monocyte THP-1 model, verbascoside could suppress DNCB-induced upregulation of CD86 and CD54...

...Ling Qin; Yu-rong Tan; Cheng-ping Hu; Xiao-ai Liu; Ruo-xi He Background: Infection of human bronchial epithelial cells (hBECs) with respiratory syncytial virus (RSV) has been shown to induce a Th lymphocyte subset drift, e.g. enhanced differentiation of Th2 and Th17 subsets, which is a classic...

...Yumi Yamada; Kenji Matsumoto; Noriko Hashimoto; Miwako Saikusa; Toshiki Homma; Shigemi Yoshihara; Hirohisa Saito Background: Respiratory syncytial virus (RSV) infection in infants with Th2 predisposition is thought to increase the risk of allergic sensitization, recurrent wheezing, and bronchial...

... previously reported that a Th2 predominance may play an important role in the fibrogenesis in chronic HP patients. A study was undertaken to evaluate whether Th2-biased immune responses were crucial during the processes of lung fibrosis in a murine model of chronic HP. Methods: Instillation of pigeon...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Bet v 1 T cell epitope Interleukin-4 Interferon-γ Th1 Th2 Th0 Pathogenesis and Management lilt Arch Allergy...

... from any ideas, methods, instructions or products referred to in the content or advertisements. Roxithromycin Asthma Macrolide Interleukin-2 Interleukin-5 Th2 Helper T lymphocytes 4 9 2009 Clinical Features, Management and Pharmacology of Allergic Diseases Int Arch Allergy...

..., instructions or products referred to in the content or advertisements. Interferon-γ Interleukin-4 Interleukin-10 Th1 Th2 Kawasaki disease International Archives of Allergy Immunology Original Paper Int Arch Allergy Immunol 1997;112:152-156 Received: May 20,1996 Accepted after revision: August...

..., quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. IgE IL-4 N-acetyl- L -cysteine Thiols Th2 IInmternamtionaAul...

...Clemens A. Dahinden; Sylvia Rihs; Brigitte Ochsensberger IL-4 and IL-13 are key immunoregulatory cytokines because of their ability to induce and amplify Th2-type immune responses and by promoting IgE formation. The basophil is a particularly prominent source of IL-4/IL-13, which are rapidly...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Hu-SCID mouse Allergic inflammation Superantigen IgE Th1 Th2 Inltmitional Arctmo of Allerg Immunology III. C ytokin e s, IgE P ro d u c tio n and M a st Cell A c tiva...

..., instructions or products referred to in the content or advertisements. CD8+ T cell Th1 Th2 Immune regulation IgE Intcmatiunal Archives of Allergy Immunology IV. T Cell Su b p o p u la tio n s, A n tig e n R ecogn ition and Immune Responses Int Arch Allergy Immunol 1997;113:160-162 B. J. Holmes PA...

..., T-nonresponder clones secreted a Th2 (IL-4, low IL-2 and low IFN-γ) or a Th1 cytokine pattern (low IL-4, high IL-2, IFN-γ levels) to peptide presentation by B cells. A comparison of EBV-B cells with activated, MHC class II expressing T cells as antigen-presenting cells (APC) revealed that T-cell...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. CD8+ T cells IgE, suppression IFN-γ IL-4 Th1 Th2 VI. Regulation of IgE Synthesis Int Arch Allergy Immunol 1992;99:362-365 Mike Kenemy Alistair Noble David Diaz...

... and Allergology Istituto di Clinica Medica 3 University of Florence. Italy Key Words Cytokines Human TH1 and TH2 Subsets Abstract Human CD4+T cell clones secreting different patterns of cytokines similar to T||l and Tn2 cells described in mice have been demonstrated. These human Th1and TH2 clones are produced...

... Cytokines Food allergy IgE Mouse model Systemic anaphylaxis Th2 Immediate hypersensitivity responses to food, commonly called food allergy, afflict 6–8% of children and ∼2–4% of adults in Westernized countries including Europe and the United States [ 1, 2 ]. Tree nut allergies in particular...

... to house dust elicited pulmonary eosinophilia in mice whereas exposure to barn dust elicited neutrophilic and lymphocytic airway inflammation. Stimulation of moDCs with urban house dust elicited expression of Th2-promoting OX40L and Jagged-1 costimulatory molecules. Dendritic cells (DCs) exposed to house...

... antibodies (Abs) affects the development of murine experimental allergic conjunctivitis (EC), a Th2-mediated disease. Methods: EC was induced in BALB/c mice by active immunization with ragweed (RW) followed by RW challenge in eye drops. Normal rat IgG (nrIgG) or anti-galectin-9 Ab was injected...