... number and co-expression of membrane-bound TNFR1/2. Cells within one tumor cell line were found to differ regarding their expression of type 1 and 2 TNFα receptors; simultaneously, cells with all 4 variants of co-expression may be present in culture. Conclusion: We demonstrated a dose-dependent effect...

... to in the content or advertisements. Atopic dermatitis 1α,24(OH) 2 D 3 Mast cell IgE TNFα VCAM-1 ...

...-hexosaminidase release assays, a leukotriene ELISA, transient transfections with reporter gene constructs of TNFα and MARC, and in addition a TNFα ELISA. Results: Consistent with previously published data in the rat basophilic cell line RBL-2H3, we find that wortmannin as well as DMV prevent the degranulation...

... the effect of stimulation of epidermal keratinocytes (KC) by inflammatory cytokines, interferon-γ (IFNγ) and/or tumor necrosis factor-α (TNFα) on the production of eosinophil chemotactic factors. Simultaneous addition of IFNγ and TNFα to culture KC synergistically increased eosinophil chemotaxis...

... addressed this issue using transient transfections of a TNFα promoter-driven reporter gene and corresponding 5′ successive deletions, the two phosphoinositol-3 kinase inhibitors demethoxyviridin and wortmannin, ELISAs and Western and Southwestern blots. Results: Nuclear factor of activated T cells (NF...