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1-20 of 40
Keywords: Signal transduction
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Journal Articles
The Roles of Mitogen-Activated Protein Kinase Pathways for Human Cultured Mast Cells
Available to PurchaseSubject Area:
Immunology and Allergy
Int Arch Allergy Immunol (2001) 124 (1-3): 169–171.
Published Online: 24 January 2012
... of these kinase pathways, we examined the participation of this kinase activation for mediator release by making use of U0126, a signal transduction, extracellular signal-regulated kinase pathway inhibitor, and SB203580, a p38 mitogen-activated protein kinase pathway inhibitor. Results: Histamine release...
Journal Articles
Effect of the H 1 -Receptor Antagonist Cetirizine on the Stimulated Expression of Adhesion Molecules and the Activation of NFκB in Human Endothelial Cells
Available to PurchaseSubject Area:
Immunology and Allergy
Int Arch Allergy Immunol (2001) 124 (1-3): 362–364.
Published Online: 24 January 2012
... to the cytokine release, dual effects are obtained by cetirizine: IL-6 and IL-8 secretion is suppressed by cetirizine in TNFα and IL-4-activated cells, whereas the IFNγ-induced suppression of IL-8 is nearly abrogated. In this context, the TNFα-induced signal transduction with regard to NFĸB and AP-1 was also...
Journal Articles
A Perspective: Regulation of IgE Receptor-Mediated Mast Cell Responses by a LAT-Organized Plasma Membrane-Localized Signaling Complex
Available to PurchaseSubject Area:
Immunology and Allergy
Juan Rivera, Ramachandran Arudchandran, Claudia Gonzalez-Espinosa, Timothy Scott Manetz, Sandhya Xirasagar
Int Arch Allergy Immunol (2001) 124 (1-3): 137–141.
Published Online: 24 January 2012
.... McKeithan TW: Kinetic proofreading in T-cell receptor signal transduction. Proc Natl Acad Sci USA 1995;92:5042–5046. 2. Racioppi L, Ronchese F, Matis LA, Germain RN: Peptide-major histocompatibility complex class II complexes with mixed agonist/antagonist properties provide evidence for ligand-related...
Journal Articles
TLR3 in Human Eosinophils: Functional Effects and Decreased Expression during Allergic Rhinitis
Available to PurchaseSubject Area:
Immunology and Allergy
Anne Månsson, Mattias Fransson, Mikael Adner, Mikael Benson, Rolf Uddman, Sven Björnsson, Lars-Olaf Cardell
Int Arch Allergy Immunol (2010) 151 (2): 118–128.
Published Online: 15 September 2009
... molecule Chemokine Signal transduction p38 MAP kinase Nuclear factor-ĸB The accumulation of eosinophils, releasing an array of tissue-damaging mediators, is a hallmark of asthma and allergy-associated inflammation [ 1, 2 ]. Viral respiratory infections are believed to contribute to allergic...
Journal Articles
Association of Leukocyte Surface Receptors with Protein Kinases
Available to PurchaseSubject Area:
Immunology and Allergy
Int Arch Allergy Immunol (1996) 110 (1): 1–6.
Published Online: 04 September 2009
..., instructions or products referred to in the content or advertisements. Receptors Protein kinases Tyrosine kinases Signal transduction International Archives of ImmAunücorl^ojagnyd M ini Review 1 - V T ; ^ . A . ~ i y_ - - j ; - Int Arch Allergy Immunol 1996;110:1-6 yâciuvHorejsi Academy o f...
Journal Articles
The Activation of the JAK2/STAT5 Pathway Is Commonly Involved in Signaling through the Human IL-5 Receptor
Available to PurchaseSubject Area:
Immunology and Allergy
Int Arch Allergy Immunol (1997) 114 (Suppl. 1): 24–27.
Published Online: 04 September 2009
... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. IL-5, human Signal transduction JAK/STAT pathway International Allergy«* Immunology Int Arch Allergy Immunol 1997; 114(suppl 1):24 27 Norihisa...
Journal Articles
Role of Tyrosine Kinases in Human Eosinophil Degranulation
Available to PurchaseSubject Area:
Immunology and Allergy
Int Arch Allergy Immunol (1997) 114 (Suppl. 1): 14–17.
Published Online: 04 September 2009
... from any ideas, methods, instructions or products referred to in the content or advertisements. Eosinophil Signal transduction Tyrosine kinase Degranulation Immunoglobulin International Archives A l l e r g y ami Immunology Int Arch Allergy Immunol 1997;114(suppl 1): 14 17 MasahikoKawa...
Journal Articles
T Lymphocytes and Aging
Available to PurchaseSubject Area:
Immunology and Allergy
Int Arch Allergy Immunol (1995) 107 (4): 491–497.
Published Online: 04 September 2009
... Cytokines T lymphocytes Signal transduction Oncogenes Cell cycle 4 9 2009 Mini-Review Int Arch Allergy Immunol 1995;107:491-497 Amiela Globerson Department of Cell Biology, Weizmann Institute o f Science. Rehovot, Israel T Lymphocytes and Aging Key Words Aging Cytokines T lymphocytes Signal...
Journal Articles
A System for Simultaneous Evaluation of the Effect of Signal Transduction Inhibitors on lnterleukin-2 Synthesis and Cell Viability in a Human T Cell Line
Available to PurchaseSubject Area:
Immunology and Allergy
Int Arch Allergy Immunol (1997) 114 (4): 316–322.
Published Online: 04 September 2009
...Sandra R. Slivka; Brian O. Claeps Background : The signal transduction pathways involved in interleukin-2 (IL-2) synthesis have become a focus of interest for pharmacological intervention. Regulation of synthesis of 1L-2 requires costimulation of two cell surface receptors, the T cell receptor...
Journal Articles
Functional Characterization of the Signal Transduction Events Mediated by FcεRI α and γ Chimeric Receptors
Available to PurchaseSubject Area:
Immunology and Allergy
Int Arch Allergy Immunol (1995) 107 (1-3): 66–68.
Published Online: 04 September 2009
... advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. FcεRI Signal Transduction Signalling RBL...
Journal Articles
Regulation of Integrin-Dependent Release in Human Lung Mast Cells and Basophils
Available to PurchaseSubject Area:
Immunology and Allergy
Int Arch Allergy Immunol (1995) 107 (1-3): 151–153.
Published Online: 04 September 2009
... cell Basophil Integrins IgE Signal Transduction © 1995 S. Karger AG, Basel 1995 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic...
Journal Articles
The lnterleukin-5/Receptor Interaction Activates Lyn and Jak2 Tyrosine Kinases and Propagates Signals via the Ras-Raf-1-MAP Kinase and the Jak-STAT Pathways in Eosinophils
Available to PurchaseSubject Area:
Immunology and Allergy
Int Arch Allergy Immunol (1995) 107 (1-3): 226–227.
Published Online: 04 September 2009
..., instructions or products referred to in the content or advertisements. Interleukin-5 Eosinophils Signal transduction Kinase Nuclear factor Pathogenesis of Asthma and Other Inflammatory Reactions Int Arch Allergy Immunol 1995;107:226-227 Rafeul Alam Konrad Pazdrak Susan Stafford Patricia Forsythe...
Journal Articles
Tyrosine Phosphorylation Regulates Activation and Inhibition of Apoptosis in Human Eosinophils and Neutrophils
Available to PurchaseSubject Area:
Immunology and Allergy
Int Arch Allergy Immunol (1995) 107 (1-3): 338–339.
Published Online: 04 September 2009
...Hans-Uwe Simon; Shida Yousefi; Kurt Blaser 4 9 2009 Apoptosis Eosinophil Neutrophil Signal transduction Tyrosine phosphorylation 1995 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages...
Journal Articles
Fc Epsilon Rl and the FcR-Beta Amplifier
Available to PurchaseSubject Area:
Immunology and Allergy
Int Arch Allergy Immunol (1997) 113 (1-3): 42–44.
Published Online: 04 September 2009
... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Fcepsilon Atopy Signal transduction International Archives of A llergyImmunology A. M. Scharenberg Jean-Pierre Kinet Laboratory o f Molecular Allergy and Immunology...
Journal Articles
Molecular Mechanisms of Defective Eosinophil Apoptosis in Diseases Associated with Eosinophilia
Available to PurchaseSubject Area:
Immunology and Allergy
Int Arch Allergy Immunol (1997) 113 (1-3): 206–208.
Published Online: 04 September 2009
.... Apoptosis Cytokines Eosinophils Fas Inflammation Signal transduction Intcmatiunal Archives of A llergyImmunology VI. Eosinophils and Eosinophil-Associated Allergic Inflam m ation Int Arch Allergy Immunol 1997:113:206-208 Hans-uweSimon Research (SIAh'K University ofZurich, Davos.Switzerland Molecular...
Journal Articles
Characterization of FcεRI Expressing Human Monocytic Cell Lines: 1. The Role of CD45 on Signal Transduction in Primary Monocytes and Cell Lines
Available to PurchaseSubject Area:
Immunology and Allergy
Int Arch Allergy Immunol (1997) 113 (4): 444–453.
Published Online: 04 September 2009
... donors. In this report human monocytic cell lines were used to test for the expression of FcεRI, reasoning that a monocytic cell line expressing FcεRI constitu-tively would be a useful tool for large scale studies on the regulation of IgE binding and signal transduction. Methods: Reverse transduction...
Journal Articles
Association of the High-Affinity Receptor for IgG with the Protein Tyrosine Kinases Hck and Lyn
Available to PurchaseSubject Area:
Immunology and Allergy
Int Arch Allergy Immunol (1995) 107 (1-3): 135.
Published Online: 04 September 2009
... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Fc receptors Signal transduction Tyrosine kinase Hck Lyn Development and Function of Effector Cells Int Arch Allergy Immunol 1995; 107:135 A.V.T. Wang P.R. Scholl R.S...
Journal Articles
Activation of Signaling Pathways and Prevention of Apoptosis by Cytokines in Eosinophils
Available to PurchaseSubject Area:
Immunology and Allergy
Int Arch Allergy Immunol (1997) 112 (1): 9–12.
Published Online: 04 September 2009
...Shida Yousefi; Kurt Blaser; Hans-Uwe Simon Inhibition of apoptosis in eosinophils by cytokines such as IL-5 and GM-CSF may play an important role in the pathogenesis of allergic and parasitic disorders. Recently, there has been some progress in the understanding of the signal transduction pathways...
Journal Articles
Recent Progress in the Elucidation of Interferon-Gamma Actions: Molecular Biology and Biological Functions
Available to PurchaseSubject Area:
Immunology and Allergy
Int Arch Allergy Immunol (1994) 104 (4): 311–316.
Published Online: 03 September 2009
... Interferon regulatory factor 1 Signal transduction Transcription control Mini Review Int Arch Allergy Immunol 1994; 104:311316 Jan Vilcek Igor C. Oliveira Department of Microbiology, New York University Medical Center, New York, N.Y., USA Recent Progress in the Elucidation of Interferon-Gamma Actions...
Journal Articles
Reconstitution of the Functional lnterleukin-5 Receptor: The Cytoplasmic Domain of Alpha-Subunit Plays an Important Role in Growth Signal Transduction
Available to PurchaseSubject Area:
Immunology and Allergy
Int Arch Allergy Immunol (1994) 104 (Suppl. 1): 36–38.
Published Online: 03 September 2009
... transfectants became responsive to human and mouse IL·5, respectively. Using the mutant α-subunits, we found that the α-subunit as well as the β-subunit participated in IL·5-mediated growth signal transduction. The FDC-P1 transfectants expressing the α-subunit which lacks its whole cytoplasmic domain did...
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