... IgE-mediated allergy ImmunoCAP Peanut allergy Recombinant allergens Peanut allergy (PA) prevalence in the USA is increasing over time [1]. Although lower prevalence has been reported in Asia [2], the adoption of a Westernized life style in Asian countries influences the reported increasing...

... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Mugwort English plantain Recombinant allergens Component resolved diagnostics Weed pollen allergy is an important contributor to type I...

... from any ideas, methods, instructions or products referred to in the content or advertisements. Aspergillus fumigatus Molecular diagnostics Mold allergy Allergic rhinitis Recombinant allergens Allergic asthma Fungi such as Aspergillus fumigatus , Alternaria alternata...

... cross-reactivity Tropomyosin Cockroach Asthma Recombinant allergens Ascaris lumbricoides Infections from intestinal parasites are still a major public health problem worldwide, leading to malnutrition, anemia, cognitive impairment, and a decreased response to vaccination [ 1...

... Recombinant allergens Cross-reactivity Olive pollen allergens Polygalacturonases (PGs) are enzymes belonging to the glycosyl hydrolase family 28 that catalyze the hydrolysis of the α-1,4-glycosidic bonds, between galacturonic acid residues localized in the polygalacturonan backbone, a main component...

... to in the content or advertisements. Allergens India Molecular allergology Recombinant allergens IgE epitope Allergy diagnosis Transgenic biosafety Allergen specific immunotherapy Clinical Allergy Review Article Int Arch Allergy Immunol 2018;177:219 237 DOI: 10.1159/000490805 Received: June 7...

...Angelika Tscheppe; Heimo Breiteneder The years 1988-1995 witnessed the beginning of allergen cloning and the generation of recombinant allergens, which opened up new avenues for the diagnosis and research of human allergic diseases. Most crystal and solution structures of allergens have been...

... of improper folding of the recombinant allergen, since in that study the Blo t 3 gene was expressed without its prepro regions. It is known that these proteases when expressed as zymogens have correct folding in addition to self-inhibition enzymatic activity [ 38,39 ]. Similarly, 57% of B. tropicalis...

... into the subepithelial tissues where they may cause increased allergic inflammation. Allergen penetration Permeability Recombinant allergens Respiratory epithelium Rhinovirus In recent years, a clear and significant association between upper respiratory tract infections with rhinovirus and an increased...

...) and chironomid flies (family Chironomidae). The females of many species of mosquitoes are blood-eating pests and dangerous vectors of disease whereas members of the similar-looking Chironomidae and Tipulidae are not. Mosquito allergy Aedes aegypti Immunoglobulin E Recombinant allergens Cross...

... Chitin Recombinant allergens House dust mites Immunoglobulin E Asthma is becoming a global public health concern due to increasing prevalence and difficulties in clinical management [ 1 ]. House dust mite (HDM) allergens are the most important cause of sensitization in asthmatic patients...

... Native PAGE Mass spectroscopy Recombinant allergens Food allergy Circular dichroism Food allergy, and in particular IgE-mediated food allergy, is a growing health problem worldwide [ 1,2 ]. Still, there is no treatment available. Identification of the most important allergens and mapping...

... tropomyosin) was dominant among patients in Brazil. However, 50% of the patients did not present reactivity to any of the recombinant allergens tested. 1 10 2011 5 12 2012 15 3 2013 © 2013 S. Karger AG, Basel 2013 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved...

... allergen (Cof a 1) was identified, expressed in Escherichia coli, and evaluated by Western blots. The frequency of sensitization was investigated by ELISA screening. Results: The Cof a 1 cDNA encoded a 32-kDa C. arabica class III chitinase. Serum IgE antibodies to the recombinant allergen were found in 3...

..., instructions or products referred to in the content or advertisements. Recombinant allergens Tropomyosin Shrimp Allergens Food allergy IgE Circular dichroism Mass spectroscopy Basophil activation test Skin prick test Shellfish allergy is a potentially life-threatening disease...

... changes such as incorrect glycosylation might hinder IgE binding, the comparison of results for human IgE show concordance for natural and recombinant allergens. The CD spectra of the recombinant allergens show a high degree of structure. Der p 15 is a member of the family 8 chitinase which have TIM...

... Recombinant allergens House dust has been known as a triggering factor of respiratory diseases, like rhinitis and asthma, for decades [ 1 ] and mites from the genus Dermatophagoides sp. have been found to be the most important allergen source in house dust [ 2 ]. House-dust mites (HDMs) represent...

... accounts for conformational modifications of the overall protein architecture that impair recognition by patients’ IgE molecules while preserving critical T cell epitopes. Recombinant allergens are entering clinical practice as highly performing diagnostic tools [ 26 ] and it is expected...

... was inhibited with the recombinant protein. Food allergy Cross-reactivity Lipid transfer protein Protein stability Recombinant allergens To test the stability of LTP as an allergen under the acidic and proteolytic conditions of the stomach, carrot rLTP was pepsin-digested. Treated rLTP...

... pollen allergy Recombinant allergens Allergen mutants Immunotherapy Almost 25% of the world’s population suffer from the symptoms of type I allergy (e.g. allergic rhinoconjunctivitis, asthma, dermatitis, food allergy, and anaphylactic shock). Allergic individuals exhibit an increased tendency...