...Martín Candia; Bernhard Kratzer; Winfried F. Pickl T lymphocytes equipped with clonotypic T cell antigen receptors (TCR) recognize immunogenic peptides only when presented in the context of their own major histocompatibility complex (MHC) molecules. Peptide loading to MHC molecules occurs...

... to develop a flexible, low-tech, cost-effective and reproducible multipeptide microarray for the research environment to enable large-scale screening of IgE epitopes of food allergens. Methods: Overlapping peptides (15-mer, 4 amino acid offset) covering the primary sequence of either peanut allergen Ara h 1...

..., instructions or products referred to in the content or advertisements. 2015 HIV Humoral response Antibody Peptides Recombinant proteins Immunoassay Microarray The analysis of HIV-specific antibody responses started with the discovery of the virus and advanced through several technological...

... antigen of Mycobacterium bovis strain bacillus Calmette-Guérin in purified protein derivative (PPD)-positive individuals. J Immunol 1995;154:4665. 3. Haselden BM, Kay B, Larche M: Immunoglobulin E-independent major histocompatibility complex-restricted T cell peptide epitope-induced late asthmatic...

...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Allergen Peptides Immunotherapy B cell epitopes Structure, three-dimensional Type I allergy...

...G. Reese; C.B. Daul; S.B. Lehrer Pen a 1, the major shrimp allergen from the brown shrimp Penaeus aztecus was purified by preparative SDS-PAGE. Peptides were generated from Pen a 1 by CNBr cleavage and endoproteinase (Lys-C, Glu-C, trypsin, alkaline protease, Arg-C, chymotrypsin) digestion...

...Philip S. Norman; Christopher F. Nicodemus; Peter S. Creticos; Robert A. Wood; Peyton A. Eggleston; Lawrence M. Lichtenstein; Anne Kagey-Sobotka; David Proud Peptides have been designed to be T cell tolerogenic for the principal allergens of the cat. These have been administered in several dosage...

...: Sequences were obtained from DNA amplified from single mites by PCR. Synthetic peptides were used to stimulate peripheral blood cells. Results: The polymorphism was limited to a few residues, but regional differences were detected in mites in Wagga. T cells were specific for the polymorphisms, so that in 16...

... of the enzyme fails to induce IgE antibodies under identical immunization conditions. Peptide mapping and T-cell stimulation experiments with 18-mer overlapping peptides locate the T-helper cell-activating epitopes in the C-terminal region of the PLA 2 protein. No T-cell epitopes are found in the area around...

...H.G. Rammensee Antigen presentation is prinicipally a function of MHC molecules, assisted by a number of adhesion and co-stimulatory molecules not immediately involved in antigen handling. Each MHC molecule, class I or class II, presents peptides derived from self or foreign proteins according...

...Jonathan B. Rothbard; Keith Marshall; Jeff Wilson; Lars Fugger; Dennis Zaller Hydrogen bonding between conserved amino acids in the HLA DR and the peptide backbone of the ligand both provide the majority of free energy of binding and force the peptide ligands to adopt a similar extended...

...Wim van’t Hof; Marjan van den Berg; Peter C. Driedijk; Rob C. Aalberse The fine specificity of IgE antibody binding to peptide 65-78 of the house dust mite major allergen Der p II was examined by comparison with binding to two peptides in which the cysteines corresponding to cys 73 and cys 78...

...: Mal d 1) as well as to Bet v 1-derived recombinant fragments and synthetic peptides were analyzed in sera from patients who had undergone SCIT for different periods of time. Results: Long-term SCIT (>1 year; cumulative dose >1,000,000 SQ units) induced more pronounced IgG1, IgG2 and IgG4...

...Ilka Senkpiehl; Matthias Marget; Martina Wedler; Stefan Jenisch; Joachim Georgi; Dietrich Kabelitz; Jörg Steinmann Anti-cyclic citrullinated peptide antibodies (anti-CCP) are a new diagnostic marker for rheumatoid arthritis (RA), which shows a specificity of 97% and a sensitivity of 81...

... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Allergy Cypress pollen Olive pollen Peptides IgE, specific T lymphocytes Pollens of Cupressus arizonica, Cupressus sempervirens and Olea europea are a major cause...