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Keywords: Ovalbumin
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Journal Articles
Int Arch Allergy Immunol (2022) 183 (4): 453–461.
Published Online: 05 April 2022
... is a potential tool to understand the molecular mechanisms underlying this therapy. Desensitized MCs exhibit internalized IgE and its FcεRI receptors in response to suboptimal doses of allergen without provoking activation. The ovalbumin (OVA) allergen exhibits altered allergenicity upon heat treatment. MC...
Journal Articles
Int Arch Allergy Immunol (2021) 182 (12): 1143–1154.
Published Online: 14 October 2021
...Hui-Hsien Pan; Jiunn-Liang Ko; Chia-Ta Wu; Hai-Lun Sun; Yeak-Wun Quek; Min-Sho Ku; Ko-Huang Lue Background: Asthma animal models provide valuable information about the pathogenesis and the treatment of asthma. An ovalbumin (OVA)/complete Freund’s adjuvant (CFA)-sensitized model was developed...
Journal Articles
Journal Articles
Int Arch Allergy Immunol (2018) 175 (3): 160–170.
Published Online: 27 January 2018
... against an epitope of the extracellular domain of TLR2, was identified. The effect of the antibody on dendritic cells was assessed by immunohistochemistry, Western blot, and flow cytometric analysis. The effect of TSP-2 in a murine asthma model induced with ovalbumin (OVA) was assessed. The model...
Journal Articles
Int Arch Allergy Immunol (2017) 173 (2): 71–83.
Published Online: 03 June 2017
... therapeutic drugs. Methods: We screened 18 TJKMs for treatment of FA symptoms in a mouse FA model induced by ovalbumin (OVA). BALB/c mice were sensitized intraperitoneally by an OVA/aluminum hydroxide gel mixture followed by 4 booster doses of oral OVA and FA symptom induction by 50 mg of OVA. TJKMs were...
Journal Articles
Int Arch Allergy Immunol (2015) 167 (3): 193–202.
Published Online: 25 August 2015
...-exacerbated food-allergy reactions is unclear. In this study, we evaluated the effect of SCG on ASP-exacerbated food-allergic reactions, as well as allergen absorption, in egg-allergic model rats. Methods: Plasma concentrations of ovalbumin (OVA) and fluorescein isothiocyanate-labeled dextran (FD-40...
Journal Articles
Int Arch Allergy Immunol (2014) 164 (4): 289–300.
Published Online: 16 September 2014
...) were sensitized by ovalbumin (OA), and their intrapulmonary airways (IA) were studied using morphometric and histochemical methods. Results: OA administration induced a significant increase in lung resistance in young animals but not in adults. The total IA wall area was significantly increased in both...
Journal Articles
Int Arch Allergy Immunol (2012) 159 (1): 33–40.
Published Online: 03 May 2012
... in an allergy model of mice. Methods: BALB/c mice with intraperitoneal ovalbumin (OVA) sensitization and/or intranasal S. aureus inoculation were prepared. The following 4 groups were designed: an OVA-sensitized S. aureus -inoculated (AR-SA) group, an OVA-sensitized uninoculated (AR) group, a nonsensitized S...
Journal Articles
Int Arch Allergy Immunol (2010) 154 (1): 33–41.
Published Online: 24 July 2010
... prediction of different disease manifestations. Commercially available preparations of the egg-white allergens, ovomucoid, ovalbumin, conalbumin and lysozyme, have been reported to contain impurities which interfere with accurate CRD. Methods: Commercial preparations of the 4 egg-white allergens were...
Journal Articles
Int Arch Allergy Immunol (2010) 153 (2): 173–181.
Published Online: 22 April 2010
... studied whether our previous observation that female mice have more pronounced airway inflammation than males is associated with more pronounced remodeling in two models of chronic allergic asthma. Methods: Male and female BALB/c mice were (1) sensitized and subsequently challenged with ovalbumin (OVA...
Journal Articles
Int Arch Allergy Immunol (2010) 152 (3): 233–242.
Published Online: 11 February 2010
... the progression of human allergic disease upon low-dose inhaled allergen exposure. Methods: Mice were primed intraperitoneally to ovalbumin (OVA) before they were exposed repeatedly to aerosols of either OVA, ryegrass (Lolium perenne) pollen extract, or both concomitantly. The sensitization to ryegrass pollen...
Journal Articles
Int Arch Allergy Immunol (1995) 108 (1): 33–38.
Published Online: 04 September 2009
... neutrophil counts impressively increased 1 h after intravenous injection of ovalbumin (OVA, 250 μg/kg) into OVA-immunized rats. The increase in neutrophil counts induced by OVA was abrogated after catecholamine depletion by reserpine. Either adrenalectomy or the α- and β-adrenoceptor antagonists phentolamine...
Journal Articles
Int Arch Allergy Immunol (1996) 111 (2): 161–165.
Published Online: 04 September 2009
... was extracted in 5 min. The maximal VPE activity had a dose-dependency similar to histamine (3 × 10 ––5 M ) but lasted longer than the histamine activity. The VPE activity was inhibited by oligomannose-glycosylated ovalbumin or avidin, as well as the oligosaccharides but not by the deglycosylated proteins...
Journal Articles
Journal Articles
Int Arch Allergy Immunol (1995) 106 (1): 46–54.
Published Online: 04 September 2009
...Harald Renz; Karlheinz Enssle; Leander Lauffer; Roland Kurrle; Erwin W. Gelfand In this study, the effect of soluble IL-4 receptors (sIL-4R) on murine allergen-induced IgE and IgG1 production was examined. Lymphocytes from mice sensitized to the allergens ragweed (RW) or ovalbumin (OVA) in vivo...
Journal Articles
Int Arch Allergy Immunol (1997) 112 (2): 196–202.
Published Online: 04 September 2009
...Hirokazu Arakawa; Kenichi Tokuyama; Hiroyuki Mochizuki; Akihiro Morikawa; Jan Lötvall Airway reactivity to bronchoconstrictor mediators changes with age. We studied the effects of maturation on airway responses provoked by allergen challenge [ovalbumin (OA) 0.05, 0.15 and 0.5 mg/kg i.v...
Journal Articles
Int Arch Allergy Immunol (1996) 109 (4): 344–351.
Published Online: 04 September 2009
...Toshiyuki Katsuki; Naoki Shimojo; Kiri Honma; Hajime Tsunoo; Yoichi Kohno; Hiroo Niimi In order to investigate T cell recognition of allergens in hen egg allergy, we have established 30 ovalbumin (OVA)-specifíc T cell lines (TCLs) from peripheral blood mononuclear cells of 6 patients with atopic...
Journal Articles
Int Arch Allergy Immunol (1995) 106 (4): 422–424.
Published Online: 04 September 2009
...Maciej Tarkowski; Pawel Gorski The effect of formaldehyde exposure on the sensitization of mice to ovalbumin was investigated. Significantly increased IgE antiovalbumin titers were found in mice sensitized intranasally to ovalbumin and exposed for 10 days to 2 mg/m 3 of formaldehyde. In contrast...
Journal Articles
Journal Articles
Int Arch Allergy Immunol (1994) 104 (1): 65–71.
Published Online: 03 September 2009
...Said Elsayed; Lene Stavseng Five successively located peptides, in region 11-70 of the major allergen of ovalbumin (OA) Gal d I (11–19, 20–33, 34–46, 47–55, 56–70), were obtained by manual solid-phase peptide synthesis. These peptides together with the previously reported OA region 1–10 comprise...