... to in the content or advertisements. 2024 Milk allergy Oral provocation test Oral tolerance Specific IgE Child Cow’s milk (CM) is one of the most common food allergens for children [ 1‒3 ] and results in anaphylaxis in infants [ 4, 5 ]. Despite early onset, numerous infants outgrow CM allergies...

...Xiaotong Yang; Rui Liang; Qianlu Xing; Xiaojuan Ma The prevalence of food allergy (FA) is increasing, and there is an urgent need to take effective measures against it. One important measure is the avoidance diet, which shows a disadvantage, especially in case of accidental exposure. Oral tolerance...

... reactivity of the degraded gliadins were evaluated in vitro. Pepsin-digested gliadin (peptic-GLI) was applied in a mouse model to investigate whether it would induce oral tolerance. Results: Degradation with pepsin decreased IgE-binding capacity and maintained T cell reactivity. Oral administration of peptic...

.... However, there is limited information on the oral tolerance-inducing ability of casein hydrolysates. Objectives: The aim of this study was to investigate whether the ingestion of casein hydrolysate induces tolerance to casein, ultimately preventing subsequent epicutaneous sensitization and development...

... in oral tolerance. All-trans retinoic acid (ATRA) has been reported to affect Treg cell differentiation. The present study examined the effects of ATRA on the induction of oral tolerance in a murine model of bronchial asthma. Methods: BALB/c mice were sensitized to and challenged with ovalbumin (OVA...

... is strict avoidance. Yet, there is considerable clinical and scientific interest in primary or secondary prevention. A major drawback of oral tolerance (OT) induction protocols, however, is the possibility of severe side effects; thus, we have formulated a hypoallergenic egg product and demonstrate its...

... Concepts lilt Arch Allergy Immunol 1997;113:219-223 Oral Tolerance in Experimental m A llltT ldlS Key Words Oral tolerance Immune regulation Experimental animals Review Background There is a continuous influx of intact macromolecules and peptide fragments of various sizes from the gut lumen across...

...Riccardo Troncone; Nives Caputo; Alessandra Zibella; Rocco Russo; Mauro Rossi; Carmen Gianfrani; Martin Stern; Herbert Wieser; Salvatore Auricchio The gut mucosa plays an important role in the induction of oral tolerance. Extending previous observations, we have here shown that serum containing gut...

... to antigen-specific slgA-mediated local immune responses as well as systemic immunity; (3) efficacious oral immunization against respiratory infections; (4) oral tolerance with respect to activation of T cells which, after declining, can be repeatedly reinduced without changes in profile or magnitude, and (5...

... from weaning abrogated this intestinally induced hypersensitivity and rendered the animals orally tolerant to OA. 16 03 1994 25 07 1994 3 9 2009 © 1994 S. Karger AG, Basel 1994 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may...

..., quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Mucosal vaccines Oral tolerance Secretory IgA Common mucosal system Oral...

... immunization with the antigen, indicating that oral tolerance was induced in the animals. The serum antibodies elicited by feeding CN were tested for binding to a panel of synthetic peptides and are shown to recognize only a limited number of potential antigenic determinants on αs1-CN. Our results suggest...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Autoimmune disease Heat shock proteins Infection Oral tolerance Peptide therapy Stefan H. E. Kaufmann Department of Immunology, University of Ulm, FRG Mini Review Int...

... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Mucosal immunoglobulins Oral tolerance Original Paper Int Arch Allergy Immunol 1992;98:64-69 Yoshiko Sugita-Konishi Christine J. Smart L.K...

... that had been developed after feeding aqueous antigen was not disturbed by subsequent oral challenge with the same antigen in the presence of oil. These results suggest that the principle of oral tolerance is a feasible strategy for prophylaxis of hypersensitization to protein antigens, where protein...

... or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Airway inflammation Der p 1 Edible vaccine House dust mite Oral tolerance Th2-type...

... for this study. Methods: Newborn piglets were exposed to ovalbumin (OVA) at dosages similar to those used in rodents to sensitise, as well as to serum containing anti-OVA antibodies. Results: Both single low doses of OVA (10 and 1,000 mg per animal) induced classical oral tolerance following a systemic challenge...

... on the immune responses has not been fully investigated. Oral tolerance is an immunologically unresponsive state induced by orally administered food antigens. Although a failure in the induction of oral tolerance would result in food allergy, the mechanisms for the induction and abrogation of oral tolerance...

...Susanne Brix; Hanne Risager Christensen; Vibeke Barkholt; Hanne Frøkiær Background: Evaluation of immune responses to food proteins in animal models requires that the animals are not already sensitized or orally tolerized against the proteins in question. Since maternal transfer of specific immune...

... of Gram-negative bacteria, is extensively present in food products like cow’s milk. It is not well established, however, how this presence of LPS affects oral tolerance induction. Methods: We studied the effect of LPS contamination in a commercial preparation of the cow milk protein β-lactoglobulin (β-LG...