... developed a novel mouse model of anaphylaxis, denoted as anaphylaxis-dependent spotted distribution of immune complex in skin (ASDIS). ASDIS manifests as distinct dotted symptoms in the skin, detectable through in vivo imaging, resembling urticarial symptoms. In this study, we investigated the potential...

... or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2021 Asthma RNA-seq <italic>Alternaria</italic> Mouse model Inflammation...

...: COS and its degrees of polymerization (DP) were selected to interact with shrimp tropomyosin (TM) and IgE was measured. A mouse model of food allergy was established by receiving shrimp TM intraperitoneally. The models were treated with different concentrations of COS. Fecal and serum histamine, serum...

...) and food allergy in a mouse model. Methods: After oral immunizations with the human food allergen lupine with the adjuvant cholera toxin (CT) (or buffer in controls), sensitization and anaphylactic responses were determined. Gastrointestinal content was collected from the distal ileum, cecum, colon...

...Yining Jin; Sarah Ebaugh; Anna Martens; Haoran Gao; Eric Olson; Perry K.W. Ng; Venu Gangur Background: Wheat allergy and other immune-mediated disorders triggered by wheat proteins are growing at an alarming rate for reasons not well understood. A mouse model to study hypersensitivity responses...

...-like protein Anti-inflammation Antifibrosis Growth factor House dust mite Allergic airway inflammation Mouse model National Institutes of Health (NIH) 10.13039/100000002 Secretoglobin (SCGB) 3A2 is a member of the SCGB gene superfamily of cytokine-like secretory proteins...

...-specific antibody responses. Conclusions: The presented mouse model for cat allergen-induced asthma exhibits hallmarks of chronic allergic asthma, like airway hyperresponsiveness, a mixed neutrophilic/eosinophilic infiltration in bronchoalveolar lavage, expression of IL-17a and signs of remodelling in lung...

... soybean globulin G4 (subunit A 5 A 4 B 3 ) and the α-subunit of the β-conglycinin 7S globulin as cross-reactive allergenswith bovine caseins [ 23,24 ]. The aim of this work was to develop a mouse model of food allergy to study in vivo the cross-reactivity between cow’s milk and soybean proteins...

..., quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Allergy Maternal immunization Mouse model Mucosa Offspring Prevention...

...) and compared to treatment with the same doses of rFel d 1 in a mouse model for cat allergy. Airway hyperresponsiveness (AHR), cytokines and cells in bronchoalveolar lavage (BAL), in vitro activation of splenocytes to rFel d 1, and Fel d 1-specific immunoglobulins were evaluated. Results: Treatment with both...

...Pascal Cadot; Isabelle Meyts; Jeroen A.J. Vanoirbeek; Bart Vanaudenaerde; Dominique M.A. Bullens; Jan L. Ceuppens Background: Mouse models of asthma suffer from the necessity to prime the animals by injections before respiratory exposure. Our aim was to develop a mouse model that mimics...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. IgE Eosinophils Latex allergy Cytokines Mouse model mRNA Original Paper lnt Arch Allergy Immunol 1994:103:370-377 Viswanath P. Kitrup Anoopa Kumar Hongyung Choi...

... the mechanism of cashew allergy, and (iii) this mouse model may be useful for further basic and preclinical studies on cashew nut allergy. 16 07 2008 21 10 2008 17 3 2009 © 2009 S. Karger AG, Basel 2009 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part...

..., instructions or products referred to in the content or advertisements. Casein Colon Cow’s milk allergy Food allergy IgE Mast cell Motility Mouse model Whey Animal models of CMA provide a tool to reveal mechanisms involved in CMA and may explore new therapeutic and preventive approaches...

.... Asthma Mouse model Mucosal tolerance Lipopolysaccharides ‘Farming effect’ Numerous studies have described the ‘farm effect’ as a protective result of rural lifestyle that lowers the risk of developing atopic disorders. However, to date, the underlying mechanisms – the key players...

... crossreactivity of IgE antibodies produced against certain aeroallergens. We tested the hypothesis that hazelnut is intrinsically capable of eliciting an allergic response using a mouse model. Methods: Groups of mice were injected intraperitoneally with hazelnut/filbert protein extract with or without alum...

... the effect of the genetic background and adjuvants on IgE reactivity in a mouse model for P. pratense allergy. Methods: Different mouse strains and F1 offspring were sensitized with P. pratense pollen extract. Serum IgE levels, the induction of specific IgE antibodies and immediate cutaneous hypersensitivity...

...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Allergic rhinitis IgE IgG1 IgG2a Immunosuppression Mouse model Nasal sensitization Phospholipase A2 Restraint...

... are also another source of IL-13. IL-13 then acts on airway epithelial cells to induce goblet cell hyperplasia and on airway smooth muscle (ASM) to induce increased responsiveness. Asthma Mouse model Airway hyperresponsiveness Over the last century, a steady increase in asthma prevalence...

... mouse model for AD. NC mice were maintained under conventional (Conv) or specific pathogen-free (SPF) conditions. Clinical symptoms, serum IgE levels and histopathology of the skin were compared between these 2 groups, and we explored their application as a model of human AD. It was found that the skin...