..., instructions or products referred to in the content or advertisements. Asthma CD4+ T cell Eosinophil Mouse Persistent inflammation of the bronchial mucosa is a prominent pathological feature of bronchial asthma [ 1 ]. Eosinophils play a central role in mucosal inflammation, although...

... Biomedicals (Aurora, Ohio, USA). For immunohistochemistry, anti-mouse CD11b (Invitrogen, Carlsbad, Calif., USA) and anti-mouse macrophages (F4/80 antigen (BMA Biomedicals, Augst, Switzerland) were purchased, and rabbit anti-mouse MBP was kindly provided by Dr. Lee (Mayo Clinic). Biotinylated rabbit polyclonal...

... corticosteroids throughout the course of CREAE in the Biozzi ABH mouse and found that major fluctuations in systemic levels coincide with the relapsing-remitting phases of the disease. Furthermore, increasing circulating adrenocorticoids through administration of the steroidal compound dexamethasone markedly...

... Phorbol ester Acute inflammation Mouse Ear edema Eicosapentaenoic acid © 1996 S. Karger AG, Basel 1996 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means...

...Els van Vliet; Markus Uhrberg; Christina Stein; Ernst Gleichmann Systemic treatment of susceptible mouse strains with HgCl 2 is known to induce elevated serum concentrations of IgG1, IgG2A, and IgE, formation of antinuclear (ANA) and antinucleolar autoantibodies (ANolA), and immune...

.... The beneficial effect of corticosteroids in bronchial asthma is partly due to their inhibitory effects on OPN production. 3 6 2009 Tissue sections were incubated overnight with goat anti-mouse polyclonal OPN antibody (dilution, 1:100; Santa Cruz Biotechnology, Santa Cruz, Calif., USA) at 4°C...

... was monitored by gravimetric analysis with a Mercer cascade impactor (In-Tox Products, Moriarty, N. Mex., USA). The mass median aerodynamic diameter and geometric standard deviations were 1.4 and 1.6 µm, respectively. The estimated daily inhaled OVA dose approximated 30–40 µg/mouse. Twenty-four hours after...

...-mouse IgE monoclonal antibodies (Biosource International, Camarillo, Calif., USA) were added. After 2 h of incubation at 37°C, plates were washed for 5 times with 300 µl of the washing buffer. After 2 h of incubation at 37°C, the reaction chromogen was generated with FAST (Sigma). After the reaction...

... cytometry, adoptive transfer of OVA specific CD4 T cells, ex vivo cytokine expression and response to methacholine challenge. Results: Chronic exposure to antigen resulted in decreased eosinophilia in 5 different mouse strains. Likewise, numbers of lung CD4 T cells expressing activation and Th2 markers...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Asthma Allergy Endotoxin Inflammation Immunoglobulin E Th2/Th1 cytokines Mouse Allergic asthma is a chronic inflammatory disease of the airways characterized...

... or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Corticosteroid Thymus and activation-regulated chemokine Mouse Th2 cell CC chemokine...

... of correlation between total and OVA-specific IgG2a suggests broader activation of IgG2a-producing B cells routinely occurs following exogenous Ag immunization. 16 06 2003 7 10 2003 27 2 2004 Mouse Antibodies Allergy IgE, Th1/Th2 Generation of an effective antibody (Ab) response...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. CD4+ T cell Mast cell Eosinophil IL-5 Mouse Chronic eosinophilic inflammation of the bronchial mucosa is a prominent pathological feature of bronchial asthma [ 1...

... events and the neuronal control of ASM contractility remains to be defined. Methods: Utilizing a well–characterized mouse model of airway inflammation and BA, we analyzed the production and function of neurotrophins in allergic asthma. To confirm these data in humans, segmental allergen provocation...