Skip Nav Destination
1-20 of 219
Keywords: Mast cellsClose
Int Arch Allergy Immunol (2023) 184 (7): 720–726.
Published Online: 04 July 2023
...Pier Giorgio Puzzovio; Bruce D. Levy; Francesca Levi-Schaffer Background: CD300a is an inhibitory receptor (IR) expressed on several leukocytes, including mast cells (MCs) and macrophages (MΦ), important cells in allergic inflammation (AI). We have previously characterized CD300a role on MCs...
Vanessa Sofia Salvador Nunes, Alex Straumann, Luis Salvador Nunes, Alain M. Schoepfer, Thomas Greuter
Int Arch Allergy Immunol (2023) 184 (5): 411–420.
Published Online: 16 May 2023
..., we discuss the pathogenesis of EoE, particularly those mechanisms beyond eosinophilic infiltration of the esophageal mucosa, non-eosinophilic inflammatory cell populations, the new disease entity EoE-like disease, variant forms of EoE, and the recently coined term mast cell esophagitis...
Haruka Asai, Ritsuko Yamamoto, Kotone Kuromiya, Reika Takamura, Wanchun Jin, Hiromasa Kurosaki, Nobuyuki Fukuishi
Int Arch Allergy Immunol (2022) 183 (10): 1050–1055.
Published Online: 08 July 2022
...Haruka Asai; Ritsuko Yamamoto; Kotone Kuromiya; Reika Takamura; Wanchun Jin; Hiromasa Kurosaki; Nobuyuki Fukuishi Background: Mast cells play a central role in allergic responses such as food allergy, asthma, allergic rhinitis, and allergic conjunctivitis. Symptoms in the early phase...
Peter Valent, Karin Hartmann, Patrizia Bonadonna, Marek Niedoszytko, Massimo Triggiani, Michel Arock, Knut Brockow
Int Arch Allergy Immunol (2022) 183 (7): 693–705.
Published Online: 23 May 2022
...Peter Valent; Karin Hartmann; Patrizia Bonadonna; Marek Niedoszytko; Massimo Triggiani; Michel Arock; Knut Brockow Mast cell activation syndromes (MCASs) are defined by systemic severe and recurrent mast cell activation, usually in form of anaphylaxis, a substantial, event-related increase...
Tomohiro Akaba, Mitsuko Kondo, Kaori Hara, Rie Mizobuchi, Kazuhiro Abe, Azusa Miyoshi, Osamitsu Yagi, Etsuko Tagaya
Int Arch Allergy Immunol (2022) 183 (4): 415–423.
Published Online: 24 November 2021
...Tomohiro Akaba; Mitsuko Kondo; Kaori Hara; Rie Mizobuchi; Kazuhiro Abe; Azusa Miyoshi; Osamitsu Yagi; Etsuko Tagaya Introduction: Eosinophilic pneumonia (EP) is characterized by a marked accumulation of eosinophils in the lungs and blood. Eosinophils and mast cells play an important role...
Int Arch Allergy Immunol (2022) 183 (2): 153–159.
Published Online: 22 September 2021
...Matteo Gelardi; Rossana Giancaspro; Michele Cassano; Domenico Ribatti Mast cells (MCs) are involved in several biological processes, such as defense against pathogens, immunomodulation, tissue repair after injury, and angiogenesis. MCs have been shown to change from protective immune cells...
Int Arch Allergy Immunol (2021) 182 (10): 917–931.
Published Online: 29 April 2021
... pathways discovered in recent years on urticaria, including the cell adhesion/chemotaxis pathway, interleukin (IL)-6/Janus tyrosine kinase/STAT pathway, IL-17/IL-23 pathway, basophil- and mast cell-related pathway, coagulation/fibrinolysis-related pathways, single-nucleotide polymorphism, and some other...
Int Arch Allergy Immunol (2021) 182 (2): 83–93.
Published Online: 07 December 2020
...Hong Wang; Yangchun Xu; Meishan Jin; Wen Yuan Background: Chronic idiopathic urticaria (CIU) represents a common skin disorder often characterized by mast cell activation and secretion of histamine and other proinflammatory factors. E-selectin (SELE) has been implicated in the pathogenesis...
Victoria Vladimirovna Zdor, Boris Izraelivich Geltser, Marina Gennadiyevna Eliseikina, Elena Vladimirovna Markelova, Yaakov Nikolayevich Tikhonov, Natalia Gennadiyevna Plekhova, Alexander V. Karaulov
Int Arch Allergy Immunol (2020) 181 (9): 715–726.
Published Online: 08 July 2020
..., the roles of mast cells and thyroid hormones in the triggering mechanism of thyroid autoimmune processes have been insufficiently investigated. This study evaluated the role of thyroid hormones and mast cells in the mechanisms of losing tolerance to thyroid autoantigens. Materials and Methods: Two groups...
Int Arch Allergy Immunol (2020) 181 (5): 357–364.
Published Online: 03 March 2020
...Adrian Y.S. Lee One of the most important blood tests in the field of allergy, mast cell tryptase has numerous diagnostic uses, particularly for anaphylactic reactions and for the diagnosis of mastocytosis. However, there are numerous other non-anaphylactic conditions where clinicians may see...
Hans-Uwe Simon, Shida Yousefi, Nina Germic, Isabelle C. Arnold, Angela Haczku, Alexander V. Karaulov, Dagmar Simon, Helene F. Rosenberg
Int Arch Allergy Immunol (2020) 181 (1): 11–23.
Published Online: 29 November 2019
... syndromes Inflammation Interleukin-5 Major basic protein M2 macrophages Mast cells Targeted therapy National Institutes of Health (NIH) 10.13039/100000002 Eosinophils, neutrophils and basophils, are subpopulations of granulocytes. Eosinophils were named by Paul Ehrlich in 1879 since...
Int Arch Allergy Immunol (2020) 181 (1): 56–70.
Published Online: 08 November 2019
...Izabela Szymczak-Pajor; Paulina Kleniewska; Joanna Wieczfinska; Rafal Pawliczak Introduction: Phospholipases are enzymes that occur in many types of human cells, including mast cells, and play an important role in the molecular background of asthma pathogenesis, and the development of inflammation...
Bradford A. Youngblood, Emily C. Brock, John Leung, Rustom Falahati, Paul J. Bryce, Jessica Bright, Jason Williams, Leonard D. Shultz, Dale L. Greiner, Michael A. Brehm, Christopher Bebbington, Nenad Tomasevic
Int Arch Allergy Immunol (2019) 180 (2): 91–102.
Published Online: 09 August 2019
...Bradford A. Youngblood; Emily C. Brock; John Leung; Rustom Falahati; Paul J. Bryce; Jessica Bright; Jason Williams; Leonard D. Shultz; Dale L. Greiner; Michael A. Brehm; Christopher Bebbington; Nenad Tomasevic Introduction: Pathologic accumulation and activation of mast cells and eosinophils...
Peter Valent, Patrizia Bonadonna, Karin Hartmann, Sigurd Broesby-Olsen, Knut Brockow, Joseph H. Butterfield, Massimo Triggiani, Jonathan J. Lyons, Joanna N.G. Oude Elberink, Michel Arock, Dean D. Metcalfe, Cem Akin
Int Arch Allergy Immunol (2019) 180 (1): 44–51.
Published Online: 28 June 2019
...Peter Valent; Patrizia Bonadonna; Karin Hartmann; Sigurd Broesby-Olsen; Knut Brockow; Joseph H. Butterfield; Massimo Triggiani; Jonathan J. Lyons; Joanna N.G. Oude Elberink; Michel Arock; Dean D. Metcalfe; Cem Akin Mast cell activation syndrome (MCAS) is a condition characterized by recurrent...
Gilda Varricchi, Francesca Wanda Rossi, Maria Rosaria Galdiero, Francescopaolo Granata, Gjada Criscuolo, Giuseppe Spadaro, Amato de Paulis, Gianni Marone
Int Arch Allergy Immunol (2019) 179 (4): 247–261.
Published Online: 28 May 2019
...Gilda Varricchi; Francesca Wanda Rossi; Maria Rosaria Galdiero; Francescopaolo Granata; Gjada Criscuolo; Giuseppe Spadaro; Amato de Paulis; Gianni Marone Mast cells are immune cells which have a widespread distribution in nearly all tissues. These cells and their mediators are canonically viewed...
Int Arch Allergy Immunol (2019) 179 (1): 53–61.
Published Online: 25 March 2019
... inflammatory skin diseases, such as psoriasis. Here, we determined the effects of mast cells on keratinocyte proliferation under stress hormone stimulation. Methods: We subcutaneously injected dexamethasone on the shaved back of mice and evaluated histological changes and keratinocyte growth factor (KGF...
Int Arch Allergy Immunol (2018) 176 (1): 55–60.
Published Online: 29 March 2018
...Domenico Ribatti The specificity of several staining methods for mast cells provides the pathologist with a useful means for the differential diagnosis of mast cell tumors. Mast cells stain metachromatically with toluidine blue with greater intensity in cells containing smaller granules. Most...
Int Arch Allergy Immunol (2017) 171 (3-4): 203–208.
Published Online: 04 January 2017
...Pazit Salamon; Irit Shefler; Alon Y. Hershko; Yoseph A. Mekori Background: It has recently been reported that mast cells (MC) can be activated to degranulate and release certain cytokines in response to direct physical contact with activated but not resting T cells or their membranes. The MAPK...
Int Arch Allergy Immunol (2017) 171 (3-4): 194–202.
Published Online: 04 January 2017
... eosinophil counts, and pulmonary test parameters. Conclusions: sBT levels may have a potential use in supporting a diagnosis of asthma in children and as a predictor of disease severity. Tryptase is a mast cell-specific serine proteinase, which has been documented as a causative factor in multiple allergic...
Mariela Jiménez, Daniel Cervantes-García, Yualli Haydee Muñoz, Alejandra García, Luis Miguel Haro Jr., Eva Salinas
Int Arch Allergy Immunol (2017) 171 (3-4): 217–226.
Published Online: 04 January 2017
... was measured. Intradermal skin reactions were developed to evaluate in vivo activation of mast cells. Peritoneal mast cells were isolated and activated by the allergen, and histamine secretion was determined. Results: GMP administration increased the amount of intestinal Lactobacillus and Bifidobacterium...