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1-20 of 98
Keywords: Mast cell
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Journal Articles
FoxP3-Positive Cells and Their Contacts with Mast Cells Are Highly Increased in Basal Cell Carcinoma
Subject Area:
Immunology and Allergy
Int Arch Allergy Immunol (2024) 185 (2): 167–169.
Published Online: 21 November 2023
...Antti P. Kaukinen; Rauno J. Harvima; Ilkka T. Harvima Introduction: The cells of the immune system are thought to contribute to the development of skin cancers, such as basal cell carcinoma (BCC). One possible mechanism may be the interaction between mast cells and regulatory T cells (Tregs...
Journal Articles
Subject Area:
Immunology and Allergy
Int Arch Allergy Immunol (2022) 183 (4): 453–461.
Published Online: 05 April 2022
...Yuka Nagata; Ryo Suzuki Background: Allergen-specific desensitization of mast cell (MC) IgE receptors (FcεRI) is an important mechanism of allergen-specific immunotherapy that enables tolerance induction via systemic desensitization. Experimental in vitro IgE-mediated MC desensitization...
Journal Articles
Subject Area:
Immunology and Allergy
Int Arch Allergy Immunol (2021) 182 (11): 1135–1142.
Published Online: 27 August 2021
...Jenni Komulainen; Hanna Siiskonen; Ilkka T. Harvima Introduction: Mast cells and their major protein, the serine proteinase tryptase, can be involved in cutaneous photodamage and carcinogenesis. The serum test of tryptase (S-tryptase) measures total tryptase protein (active tryptase and inactive...
Journal Articles
Subject Area:
Immunology and Allergy
Int Arch Allergy Immunol (2016) 170 (4): 257–261.
Published Online: 06 October 2016
.... Anaphylaxis Antibody-secreting cell Immunoglobulin E Mast cell Proteasome inhibitor National Institutes of Health (NIH) 10.13039/100000002 Since peanut allergy, often life-long, is mediated by immunoglobulin E (IgE), targeting plasma cells (PCs) as an approach to decrease IgE seems...
Journal Articles
Subject Area:
Immunology and Allergy
Naruto Noma, Masataka Asagiri, Masatoshi Takeiri, Saori Ohmae, Kenji Takemoto, Keiko Iwaisako, Nagahiro Minato, Mari Maeda-Yamamoto, Siro Simizu, Kazuo Umezawa
Int Arch Allergy Immunol (2015) 166 (2): 84–90.
Published Online: 05 May 2015
...Naruto Noma; Masataka Asagiri; Masatoshi Takeiri; Saori Ohmae; Kenji Takemoto; Keiko Iwaisako; Nagahiro Minato; Mari Maeda-Yamamoto; Siro Simizu; Kazuo Umezawa Background: Stimulation with antigen and IgE is known to activate NF-κB in mast cells. In the present research, we studied the role of NF...
Journal Articles
Subject Area:
Immunology and Allergy
Arnold S. Kirshenbaum, Amy Petrik, Rosemary Walsh, Tara L. Kirby, Sury Vepa, Danny Wangsa, Thomas Ried, Dean D. Metcalfe
Int Arch Allergy Immunol (2014) 164 (4): 265–270.
Published Online: 03 September 2014
...Arnold S. Kirshenbaum; Amy Petrik; Rosemary Walsh; Tara L. Kirby; Sury Vepa; Danny Wangsa; Thomas Ried; Dean D. Metcalfe Background: In 2003, this laboratory published an account of the human mast cell line LAD2 (Laboratory of Allergic Diseases 2) that expressed FcεRI, responded to recombinant...
Journal Articles
Subject Area:
Immunology and Allergy
Rikiya Koketsu, Masao Yamaguchi, Maho Suzukawa, Yusuke Tanaka, Hiroyuki Tashimo, Hidenori Arai, Hiroyuki Nagase, Kenji Matsumoto, Hirohisa Saito, Chisei Ra, Kazuhiko Yamamoto, Ken Ohta
Int Arch Allergy Immunol (2013) 161 (Suppl. 2): 23–31.
Published Online: 29 May 2013
...Rikiya Koketsu; Masao Yamaguchi; Maho Suzukawa; Yusuke Tanaka; Hiroyuki Tashimo; Hidenori Arai; Hiroyuki Nagase; Kenji Matsumoto; Hirohisa Saito; Chisei Ra; Kazuhiko Yamamoto; Ken Ohta Background: Basophils and mast cells are important initiator/effector cells capable of rapidly responding to IgE...
Journal Articles
Subject Area:
Immunology and Allergy
Junichi Hosokawa, Kotaro Suzuki, Daiki Nakagomi, Tomohiro Tamachi, Hiroaki Takatori, Akira Suto, Hiroshi Nakajima
Int Arch Allergy Immunol (2013) 161 (Suppl. 2): 37–43.
Published Online: 29 May 2013
...Junichi Hosokawa; Kotaro Suzuki; Daiki Nakagomi; Tomohiro Tamachi; Hiroaki Takatori; Akira Suto; Hiroshi Nakajima Background: Mast cells are known to play a pivotal role in allergic diseases by releasing granules containing histamine and other preformed chemical mediators. Cross-linking of high...
Journal Articles
Subject Area:
Immunology and Allergy
Anna Sala-Cunill, Victoria Cardona, Moises Labrador-Horrillo, Olga Luengo, Olga Esteso, Teresa Garriga, Maria Vicario, Mar Guilarte
Int Arch Allergy Immunol (2013) 160 (2): 192–199.
Published Online: 15 January 2013
.... 2012 Emergency Food allergy Adrenaline Epinephrine Anaphylaxis Mast cell Tryptase Drug allergy Diagnosis of anaphylaxis is based on suggestive clinical symptoms after exposure to a potential triggering agent or event [ 1, 2 ]. The clinical diagnosis may be supported by in vitro...
Journal Articles
Subject Area:
Immunology and Allergy
Int Arch Allergy Immunol (2013) 160 (3): 259–264.
Published Online: 17 October 2012
...Rika Nakamura; Ryosuke Nakamura; Reiko Adachi; Yasuharu Itagaki; Yuma Fukutomi; Reiko Teshima Background: We performed an in vitro elicitation test to determine the ability of different types of wheat-allergic patients’ IgE to induce humanized mast cell activation after the addition of various time...
Journal Articles
Subject Area:
Immunology and Allergy
Int Arch Allergy Immunol (2001) 124 (1-3): 166–168.
Published Online: 24 January 2012
... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Allergy Mast cell Local IgE synthesis FcεRI Mast cells play a central role in the immediate-phase allergic...
Journal Articles
Subject Area:
Immunology and Allergy
Int Arch Allergy Immunol (2001) 124 (1-3): 16–19.
Published Online: 24 January 2012
...Yukihiko Kitamura; Eiichi Morii; Hideki Ogihara; Tomoko Jippo; Akihiko Ito We have used various mouse mutants for studying the development of mast cells. The bone marrow origin of mast cells was shown by using giant granules of beige mice as a marker. Mast cell-deficient W/W v and Sl/Sl d mice...
Journal Articles
Subject Area:
Immunology and Allergy
Int Arch Allergy Immunol (2001) 124 (1-3): 142–145.
Published Online: 24 January 2012
...T.-J. Lin; T.B. Issekutz; Jean S. Marshall Background: Mast cell numbers and expression of chemokines are known to increase in the context of angiogenesis and inflammation, but the mechanisms by which this occurs are not understood. Stromal-derived factor-1 (SDF-1) is an important chemokine...
Journal Articles
Subject Area:
Immunology and Allergy
Int Arch Allergy Immunol (2001) 124 (1-3): 160–162.
Published Online: 24 January 2012
...J.W. Coleman; B.M. Brooks; N.C. Eastmond; R.D. Koranteng Although IFN-γ does not act directly on mast cells to control degranulation, biotinylated mouse IFN-γ did bind to both wild-type and IFN-γ receptor knockout mast cells [ 8 ]showing that binding is through a non-receptor mechanism. The mast...
Journal Articles
Subject Area:
Immunology and Allergy
Hironori Sagara, Sohei Makino, Naomi Chibana, Mayumi Ota, Stephen T. Holgate, Martin K. Church, Takeshi Fukuda
Int Arch Allergy Immunol (2001) 124 (1-3): 371–376.
Published Online: 24 January 2012
...Hironori Sagara; Sohei Makino; Naomi Chibana; Mayumi Ota; Stephen T. Holgate; Martin K. Church; Takeshi Fukuda Inflammation of the airways is a cardinal feature of asthma. It has recently been recognized that mast cells may contribute to this process by cytokine secretion. Activation of a number...
Journal Articles
Subject Area:
Immunology and Allergy
Int Arch Allergy Immunol (2001) 124 (1-3): 304–306.
Published Online: 24 January 2012
...T. Zuberbier; A. Lelke; K. Sänger; P. Welker; S. Guhl; B.M. Henz Tissue mast cells are known to be increased and activated in patients with atopy [ 1 ], but it is unclear whether these changes constitute a basic property or only a reactive change of the atopic state. We have previously shown...
Journal Articles
Subject Area:
Immunology and Allergy
I. Alvarez-Twose, D. González-de-Olano, L. Sánchez-Muñoz, A. Matito, M. Jara-Acevedo, C. Teodosio, A. García-Montero, J.M. Morgado, A. Orfao, L. Escribano
Int Arch Allergy Immunol (2012) 157 (3): 275–280.
Published Online: 28 October 2011
...I. Alvarez-Twose; D. González-de-Olano; L. Sánchez-Muñoz; A. Matito; M. Jara-Acevedo; C. Teodosio; A. García-Montero; J.M. Morgado; A. Orfao; L. Escribano Background: A variable percentage of patients with systemic mast cell (MC) activation symptoms meet criteria for systemic mastocytosis (SM). We...
Journal Articles
Subject Area:
Immunology and Allergy
Int Arch Allergy Immunol (1999) 119 (3): 205–211.
Published Online: 14 June 2011
... months after primary immunization. Enhanced secretory responses to nerve stimulation, increased mucosal mast cell numbers, as well as elevated IgE titers were also induced and may have contributed to the overall responsiveness of the intestine to antigen challenge. Conclusions: Our findings indicate...
Journal Articles
Subject Area:
Immunology and Allergy
Martin Metz, Elizabeth Doyle, Carsten Bindslev-Jensen, Takeshi Watanabe, Torsten Zuberbier, Marcus Maurer
Int Arch Allergy Immunol (2011) 155 (4): 355–360.
Published Online: 22 February 2011
... advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Mast cell Urticaria Allergy Sepsis...
Journal Articles
Subject Area:
Immunology and Allergy
Martin Metz, Sabine Altrichter, Elena Ardelean, Birgit Keβler, Karoline Krause, Markus Magerl, Frank Siebenhaar, Karsten Weller, Torsten Zuberbier, Marcus Maurer
Int Arch Allergy Immunol (2011) 154 (2): 177–180.
Published Online: 24 August 2010
... of omalizumab other than IgE capture, especially in regard to the inhibition of mast cell degranulation. Further research is necessary to clarify the mechanism of action of omalizumab in patients with physical urticarias. Another focus of interest will be to identify the few patients which will not profit from...
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