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Keywords: Leukotrienes
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Journal Articles
Journal Articles
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Journal Articles
Int Arch Allergy Immunol (1996) 111 (3): 299–306.
Published Online: 04 September 2009
... exposed to aerosols, either saline or CRa, for 4 weeks, after a sham or S-SC smoke pretreatment. Anaphylactic antibodies were measured by passive cutaneous anaphylaxis (PCA) assay and by skin test. Animals were challenged with aerosol CRa on day 35, and lung function and leukotrienes (LTB 4 and LTC 4 /D 4...
Journal Articles
Int Arch Allergy Immunol (1996) 110 (1): 52–56.
Published Online: 04 September 2009
...Manfred Köller; Ralf A. Hilger; Jean Pierre Rihoux; Wolfgang König Leukotrienes are potent lipid mediators involved in acute and chronic inflammatory processes and allergic inflammation. Cetirizine is an H 1 -receptor antagonist used in the treatment of allergic symptoms. We analyzed the effect...
Journal Articles
Journal Articles
Int Arch Allergy Immunol (1995) 108 (2): 158–164.
Published Online: 04 September 2009
...Claudio Denzlinger; Christopher Haberl; Wolfgang Wilmanns Anaphylactic reactions are systemic, potentially life-threatening allergic reactions. In several animal models, evidence has been presented that leukotrienes may be of major pathophysiological significance. The aim of the present study...
Journal Articles
Int Arch Allergy Immunol (1996) 110 (4): 318–324.
Published Online: 04 September 2009
... of these reactions, persulfates obviously show some characteristics of skin-sensitizing as well as respiratory allergens. We measured the effect of APS on the release of inflammatory mediators, i.e. leukotriene B 4 (LTB 4 ), from human polymorphonuclear neutrophils (PMN). The effect of the persulfate was analyzed...
Journal Articles
Journal Articles
Int Arch Allergy Immunol (1997) 112 (4): 392–399.
Published Online: 04 September 2009
...-hexosaminidase release assays, a leukotriene ELISA, transient transfections with reporter gene constructs of TNFα and MARC, and in addition a TNFα ELISA. Results: Consistent with previously published data in the rat basophilic cell line RBL-2H3, we find that wortmannin as well as DMV prevent the degranulation...
Journal Articles
Int Arch Allergy Immunol (1995) 107 (1-3): 423–424.
Published Online: 04 September 2009
...Peter H. Howarth; K. Harrison; L. Lau Allergic rhinitis 5-lipoxygenase inhibition Leukotrienes 4 9 2009 1995 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized...
Journal Articles
Int Arch Allergy Immunol (1995) 107 (1-3): 432–434.
Published Online: 04 September 2009
... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Phospholipase A 2 Leukotrienes Prostaglandins Cytokines Inflammation Clinical Features, Management...
Journal Articles
Int Arch Allergy Immunol (1995) 107 (1-3): 349–350.
Published Online: 04 September 2009
...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Allergy Basophils Histamine Leukotrienes Molds Effectors and Pathogenesis of Allergic Diseases Int Arch Allergy...
Journal Articles
Int Arch Allergy Immunol (1997) 113 (1-3): 312–315.
Published Online: 04 September 2009
... increases in prostaglandin F 2α (PGF 2α ), thromboxane B 2 (TXB 2 ) and leukotriene B 4 (LTB 4 ) (p < 0.05). Moreover, we found an increase in the concentration of LTC 4 / D 4 /E 4 in the supernatant of ozone-exposed mucosal samples, which however does not reach statistical significance...
Journal Articles
Int Arch Allergy Immunol (1994) 105 (2): 135–142.
Published Online: 03 September 2009
... pharmacological agents implicated prostaglandins and leukotrienes as the principal mediators of the antigen-induced ΔI sc , with 5-HT also playing a role. Neural blockade with tetrodotoxin or blockade of histamine H 1 receptors with diphen-hydramine failed to inhibit the colonic immune response. Distal colon from...
Journal Articles
Int Arch Allergy Immunol (1993) 100 (3): 268–273.
Published Online: 02 September 2009
...S. Aibara; M. Mori; W. Tsukada We studied the leukotriene (LT) antagonistic activity of DS-4574 in vivo and the inhibitory effect of this compound on antigen-induced bronchoconstriction in actively sensitized guinea pigs. Bronchoconstriction induced by LTD 4 was inhibited by intravenous and oral...
Journal Articles
Journal Articles
Int Arch Allergy Immunol (1992) 99 (2-4): 319–322.
Published Online: 02 September 2009
... capable of modulating histamine and leukotriene release in human lung mast cells. KL increases the IgE-dependent mediator release 2- to 3-fold without inducing substantial mediator release over the control by itself in freshly isolated cells. By contrast, this study shows that KL becomes a potent...
Journal Articles
Int Arch Allergy Immunol (1992) 98 (2): 169–177.
Published Online: 02 September 2009
... leukotriene (LT) C4/D4 (10–40 ng/10 6 cells) and LTB4 (2–5 ng/10 6 cells) for over 100 days of culture. In one experiment, bone marrow-derived mast cells after 150 days of culture began to produce an IL3-like substance and proliferated exponentially without exogenous IL3. 2 9 2009 © 1992 S. Karger...
Journal Articles
Int Arch Allergy Immunol (1992) 98 (2): 146–152.
Published Online: 02 September 2009
... intravenously and orally, the ID 50 values being 0.04 and 0.89 mg/kg, respectively. DS-4574 also inhibited antigen-induced histamine and leukotriene release in passive peritoneal anaphylaxis following oral administration. In addition, this compound prevented antigen-induced histamine release in passively...