...-2B injury by inhibiting HIF-1α/NLRP3 pathway. Conclusion: These results suggested that IL-12 contributes to the development of asthma by targeting HIF-1α/NLRP3 pathway through Runx3, thus providing a novel strategy for asthma therapy. Interleukin-12 Runx3 HIF-1α/NLRP3 Asthma Inflammation...

..., instructions or products referred to in the content or advertisements. Interleukin-12 Interleukin-12 receptor β 1 and β 2 Interferon-=γ IgE Atopic gene Mutation of IL-12Rβ 2 chain gene The atopic patient has a predisposition to selective synthesis of IgE antibodies to common environmental...

... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Asthma Interleukin-4 Interleukin-12 Cytokines Murine C. Kips* G. G. Brusselle G.FJoos /I. Pelentan R. R. Devosb J. H. Tavernierh R.A. Pauwels Department o f Respiratory...

...H.C. Maguire, Jr. Interleukin-12 (IL-12) is a heterodimeric cytokine tha thas pleiotropic effects on the immune response. We have studied the effect of recombinant IL-12 on allergic contact dermatitis in the mouse. IL-12 substantially up-regulates the induction of sensitivity to the contact...

..., instructions or products referred to in the content or advertisements. Interleukin-4 receptor Interleukin-12 Immunoglobulins Low-affinity immunoglobulin E receptor (CD23) Original Paper Int Arch Allergy Immunol 1995;106:124-133 Brigitte König Karsten Neuber Wolfgang König Medizinische Mikrobiologie...

.... Airway inflammation Asthma Dendritic cells Dermatophagoides farinae Interleukin-12 Respiratory syncytial virus Allergic asthma is a chronic inflammatory pulmonary disease characterized by airway narrowing due to eosinophilic airway inflammation, mucus hypersecretion and airway...

... from any ideas, methods, instructions or products referred to in the content or advertisements. Lactobacillus pentosus strain S-PT84 Lactic acid bacteria Heat-killed Interleukin-12 Interleukin-10 Immunoglobulin E T helper type 1 T helper type 2 Natural killer cell Active cutaneous...

... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Oral tolerance Interleukin-12 Antibody production Antiallergic food IL-12 is a cytokine which induces a Th1 response and contributes to enhanced cellular immunity...

... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Eosinophils Interleukin-12 EPO Matrigel Migration Apoptosis Survival Eosinophil infiltration of airway mucosa and blood eosinophilia...

... Sci 1998;81:48–53. 37. Yasui H, Shida K, Matsuzali T, Yokokura T: Immunomodulatory function of lactic acid bacteria. Antonie Van Leeuwenhoek 1999;76:383–389. 38. Kato I, Tanaka K, Yokokura T: Lactic acid bacterium potently induces the production of interleukin-12...

... to in the content or advertisements. Dietary nucleotides T helper cells OVA-specific cytokine production Interleukin-12 Serum OVA-specific IgE In ovalbumin (OVA)-specific T cell receptor (TCR) transgenic (OVA-TCR Tg) mice, most of the peripheral T cells express the transgenic TCR. Depending...

... and costimulatory signals. The CD28 receptor on T cells with its ligand B7 represents one of the most important examples of this costimulation. Interleukin 12 (IL–12) has a strong synergistic effect with the B7–1/CD28 interaction on inducing proliferation and cytokine production in T cells. Methods: In this study...

...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Interleukin-12 Interleukin-5 Granulocyte/macrophage colony-stimulating factor Interferon-γ Th1 cells Th2 cells Asthma...