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1-20 of 110
Keywords: Inflammation
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Journal Articles
Subject Area:
Immunology and Allergy
Int Arch Allergy Immunol 1–12.
Published Online: 22 November 2024
... pulmonary disease. Despite its crucial biological functions, the mechanisms by which IL-41 mitigates lipopolysaccharide (LPS)-induced acute lung injury (ALI) are not well understood. This study aimed to elucidate the protective effects of IL-41 against LPS-induced inflammation and apoptosis in a murine...
Journal Articles
Subject Area:
Immunology and Allergy
Int Arch Allergy Immunol 1–9.
Published Online: 16 September 2024
...Lei Li; Jihui Sun; Qian Li; Kexin Sun; Jianhua Jiang Introduction: Chronic obstructive pulmonary disease (COPD) is a progressive and largely irreversible disease. Current therapeutic approaches for COPD are limited in terms of slowing disease progression and suppressing pulmonary inflammation...
Journal Articles
Subject Area:
Immunology and Allergy
Haruka Asai, Koichi Kato, Mayu Miyasaka, Kaho Hatsukawa, Nanami Murakami, Naoko Takeda, Junna Abe, Yutaka Aoyagi, Yuka Kohda, Ming-Yu Gui, Yong-Ri Jin, Xu-Wen Li, Yukio Hitotsuyanagi, Koichi Takeya, Tsugunobu Andoh, Hiromasa Kurosaki, Nobuyuki Fukuishi
Int Arch Allergy Immunol (2024) 185 (9): 836–847.
Published Online: 24 May 2024
..., instructions or products referred to in the content or advertisements. 2024 Kamebakaurin Mast cells Allergy Inflammation Spleen tyrosine kinase Rabdosia japonica (Brum.) H.Hara and Rabdosia excisa (Maxim.) H.Hara are distributed mainly across Japan, China, and Southeast Asia...
Journal Articles
Subject Area:
Immunology and Allergy
Int Arch Allergy Immunol (2024) 185 (5): 411–424.
Published Online: 23 February 2024
...Danyang Li; Jisheng Zhang; Lin Wang; Xudong Yan; Jiajia Zi; Xiaoyun Du; Longgang Yu; Yan Jiang Introduction: Chronic rhinosinusitis with nasal polyps (CRSwNP) is an immunologic disease, and pyroptosis, an inflammation-based cellular death, strictly modulates CRSwNP pathology, whereas the pyroptosis...
Journal Articles
Eva Untersmayr, Carina Venter, Peter Smith, Johanna Rohrhofer, Cebile Ndwandwe, Jurgen Schwarze, Emer Shannon, Milena Sokolowska, Corinna Sadlier, Liam O’Mahony
Int Arch Allergy Immunol (2024) 185 (5): 489–502.
Published Online: 22 January 2024
... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2024 Long COVID Severe acute respiratory syndrome coronavirus 2 Inflammation Microbiota Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV...
Journal Articles
Subject Area:
Immunology and Allergy
Int Arch Allergy Immunol (2024) 185 (4): 301–310.
Published Online: 04 January 2024
...-eicosatetraenoic acid OXE receptor Inflammation Allergy Antagonist Arachidonic acid (AA) metabolism has two pathways: one is the formation of prostaglandins and thromboxanes, and the other is 5-lipoxygenase (LO). The latter is responsible for the synthesis of leukotrienes [ 1 ]. The 5-LO pathway...
Journal Articles
Subject Area:
Immunology and Allergy
Int Arch Allergy Immunol (2024) 185 (3): 201–211.
Published Online: 08 December 2023
... attenuated the production of inflammatory cytokines in nasal epithelial cells. Furthermore, elevated FGD5-AS1 expression significantly alleviated AR symptoms by reducing nasal epithelial apoptosis and inflammation. MiR-223-3p was identified as a direct target of FGD5-AS1. Moreover, miRNA-223-3p directly...
Journal Articles
Subject Area:
Immunology and Allergy
Lingxuan Zhou, Xiaohui Yuan, Yongyan Hu, Siyu Zhu, Junxiang Li, Chenyu Wang, Miao Jing, Lingling Liu, Zhe Xu, Zuotao Zhao, Jiahui Zhao
Int Arch Allergy Immunol (2024) 185 (2): 170–181.
Published Online: 14 November 2023
...-1α, IL-4, IL-5, IL-13, and IL-31 in the ears. In human fibroblasts, HMGB1 caused nuclear translocation of NF-kB, and the nuclear translocation could be inhibited by pre-treatment of HMGB1 with cIY8, suggesting that NF-κB signaling pathway participates in the HMGB1-induced inflammation of AD...
Journal Articles
Subject Area:
Topic Article Package: ADC (Antibody-Drug Conjugates)
,
Karger e-Journal Backfile Collection 2023
,
Immunology and Allergy
Int Arch Allergy Immunol (2023) 184 (5): 447–459.
Published Online: 16 May 2023
...Juan Yuan; Ruina Li; He Song; Xi Liu Introduction: Influenza A virus (IAV) infection causes severe lung inflammation and injury, particularly in children. Sirtuin3 (Sirt3) was confirmed to be effective in protecting the lung against injury. This study aims to explore the function and mechanism...
Journal Articles
Subject Area:
Topic Article Package: ADC (Antibody-Drug Conjugates)
,
Karger e-Journal Backfile Collection 2023
,
Immunology and Allergy
Int Arch Allergy Immunol (2023) 184 (5): 471–480.
Published Online: 16 May 2023
...: Our results showed that the AR model cells were successfully created by Derp1 stimulation and that BCK1 was expressed at low levels in the nasal epithelial tissues of AR patients and AR model cells. We also found that overexpression of RBCK1 could prevent inflammation and the migration and invasion...
Journal Articles
Subject Area:
Immunology and Allergy
Int Arch Allergy Immunol (2022) 183 (12): 1231–1240.
Published Online: 12 October 2022
... from any ideas, methods, instructions or products referred to in the content or advertisements. Interleukin-12 Runx3 HIF-1α/NLRP3 Asthma Inflammation Asthma is one of the commonest respiratory diseases affecting respiratory health throughout life [1]. It has become a global public...
Journal Articles
Subject Area:
Immunology and Allergy
Int Arch Allergy Immunol (2022) 183 (9): 946–952.
Published Online: 06 September 2022
...Weifeng Zong; Yuxia Liang; Yuqing Mo Background: Asthma is a common chronic airway inflammation in the world. The aim of this study was to investigate the expression of SERPINB10 in induced sputum and its correlation with airway type 2 inflammation in asthma. Methods: We recruited 90 subjects...
Journal Articles
Subject Area:
Immunology and Allergy
Int Arch Allergy Immunol (2022) 183 (10): 1127–1136.
Published Online: 30 May 2022
...Jia Li; Xuyan Wang; Yufei Su; Shuwen Hu; Jing Chen Asthma is a chronic airway disease involving airway inflammation and remodeling. Studies showed that tripartite motif-containing protein 33 (TRIM33) regulated natural immunity, inflammation, and pulmonary fibrosis. However, the role and regulatory...
Journal Articles
Subject Area:
Immunology and Allergy
Hideki Inoue, Kaho Akimoto, Hitoshi Ikeda, Hiroki Sato, Tomoki Uno, Yoshitaka Uchida, Tomoko Kawahara, Yosuke Fukuda, Kuniaki Hirai, Yoshito Miyata, Tetsuya Homma, Shin Ohta, Mayumi Yamamoto, Shintaro Suzuki, Akihiko Tanaka, Hironori Sagara
Int Arch Allergy Immunol (2022) 183 (2): 142–152.
Published Online: 08 February 2022
... airway epithelial damage following airway inflammation and excessive mucus secretion, which can lead to severe asthma with fungal sensitization (SAFS). Comprehensive gene expression analysis in Alternaria -exposed mouse airways, a model of SAFS, has not been conducted. Methods: BALB/c mice received...
Journal Articles
Subject Area:
Immunology and Allergy
Int Arch Allergy Immunol (2022) 183 (5): 566–571.
Published Online: 26 January 2022
... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Cytokines Bariatric surgery Inflammation Diabetes Obesity predisposes to several severe diseases such as hyperlipidemia, diabetes mellitus, cancer...
Journal Articles
Enhanced Infiltration of Central Memory T Cells to the Lung Tissue during Allergic Lung Inflammation
Subject Area:
Immunology and Allergy
Mashael Alabed, Asma Sultana Shaik, Narjes Saheb Sharif-Askari, Fatemeh Saheb Sharif-Askari, Shirin Hafezi, Bushra Mdkhana, Elaref Ratemi, Saleh Al-Muhsen, Qutayba Hamid, Rabih Halwani
Int Arch Allergy Immunol (2022) 183 (2): 127–141.
Published Online: 20 October 2021
... distribution of effector memory (T EM ) and central memory (T CM ) T-cell subtypes, their differentiation, and their contribution to the persistence of lung tissue inflammation during asthma are not well understood. Interestingly, an increase in survival and persistence of memory T cells was reported...
Journal Articles
Subject Area:
Immunology and Allergy
Int Arch Allergy Immunol (2021) 182 (10): 997–1007.
Published Online: 28 September 2021
...Zhenyang Si; Biao Zhang Background: Cough-variant asthma (CVA) is a special type of asthma, solely manifesting with coughing. Studies suggest that airway inflammation is associated with CVA pathogenesis. Amygdalin is found to have an anti-inflammatory potential, while how it affects CVA remains...
Journal Articles
Subject Area:
Immunology and Allergy
Int Arch Allergy Immunol (2021) 182 (5): 408–416.
Published Online: 04 November 2020
...Ding Yu; Wang Wei; Yang Hefeng; Li Weihao; Qu Qianqian; Li Song Introduction: Osteoarthritis (OA) is a common musculoskeletal disease characterized by pain, stiffness, limited activity, occasional effusion, and local inflammation. MiR-146 is one of the noncoding RNA closely related to OA...
Journal Articles
Subject Area:
Immunology and Allergy
Juman Liu, Yinhui Chen, Feng Zhang, Xi Peng, Xiaoning Mao, Weihong Lu, Ruijian Wu, Binglong Huang, Yanmin Bao, Lian Ma, Yuge Huang, Xingliang Zhang
Int Arch Allergy Immunol (2020) 181 (8): 594–605.
Published Online: 11 August 2020
.... But the role of miRNA in regulating asthmatic inflammation is largely unclear. We previously reported that miR-3162-3p in the peripheral blood of children with asthma was obviously upregulated compared to that in healthy children. This study aimed to elucidate the role of miR-3162-3p in pulmonary inflammation...
Journal Articles
Subject Area:
Immunology and Allergy
Int Arch Allergy Immunol (2020) 181 (8): 618–623.
Published Online: 09 June 2020
... cytokine of T helper 17 (Th17) cells. Th17 cells are involved in the development of autoimmune disease, inflammation, and tumors. Although IL-17D is similar to IL-17A in its ability to induce inflammatory cytokine production, there are fewer studies on IL-17D. Recently, the role of IL-17D in tumors...
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