... strategy. In this study, we tested the capability of titanium dioxide (TiO 2) to degrade allergens upon activation by a photocatalyst. House dust mite (HDM), cat, and oak pollen extracts were incubated with TiO 2 powder for 24 h in either dark or light exposure. Methods: Changes in protein and allergen...

...Haoyang Hu; Qiao-Zhi Qin; Wei Zheng; Zhi-Qiang Xu; Xiang Chen Introduction: House dust mite is the primary trigger of allergic respiratory diseases worldwide, and allergen-specific immunotherapy (AIT) is the only disease-modifying treatment in the clinic. The use of allergen molecules instead...

... and FcεRIα (the alpha subunit of the high-affinity IgE receptor) expression in the blood samples with various house dust mite (HDM)-sIgE levels were determined by flow cytometry. Basophil reactivity and SHIP-1 (a molecule related to the IgE/FcεRI signaling pathway) expression were analyzed after stimulation...

... established. In this study, we investigated the noninferiority of hypertonic sodium chloride (S) versus L as a carrier for house dust mite (HDM) allergen to simplify manufacturing, reduce costs, and allow for wider use. Methods: Using a participant-blinded, sham exposure-controlled, single-arm, sequential...

...Yunbo Gao; Jingyun Li; Xu Xu; Chengshuo Wang; Yuan Zhang; Luo Zhang Introduction: House dust mite (HDM) is an important source of airborne allergens in China as it contains several allergenic components that can cause allergic rhinitis (AR) and other allergic diseases. This study aimed to determine...

... with allergic rhinitis subjects and healthy controls sensitized to mosquito extract was performed. Sensitization to mosquito and house dust mites was evaluated using skin prick test (SPT) and antibody determination by ELISA. Nasal provocation test (NPT) with whole-body extract was used to determine clinical...

...Jorge Sánchez; Víctor-Daniel Calvo; Juan-Felipe López; Libia-Susana Díez; Leonardo Puerta Background: Patients with allergic rhinitis to house dust mites have an increased risk of shrimp allergy. Der p 10 is a candidate biomarker to predict the risk of shrimp allergy among allergic rhinitis...

... treatment. [email protected] Subcutaneous immunotherapy (SCIT) using standardized allergen vaccine is a classical causal treatment for type 1 allergy. House dust mite (HDM) is the most important cause of allergy in China [ 3 ], and HDM Dermatophagoides pteronyssinus (DP) SCIT has been shown...

... symptoms. Currently, there is no convincing explanation why some people with positive allergen tests do not show symptoms. We aimed to investigate the house dust mite (HDM)-specific IgE and IgG4 repertoire in asymptomatic HDM-sensitized subjects and HDM-induced allergic rhinitis (AR) patients. Methods...

...Susana Diez; Leonardo Puerta; Dalgys Martínez; María Muñoz; Karen Hernández; Jorge Sánchez Introduction: Cross-reactivity between shrimp and house dust mite (HDM) proteins has been widely documented. In tropical region, shrimp (5–15%) and mite sensitization (80–95%) is prevalent in allergic...

... and the modified Lund-Kennedy (MLK) scoring system were performed to describe and evaluate the therapeutic effect of SLIT. Methods: A total of 105 patients with AR induced by house dust mites were enrolled and treated with standardized Dermatophagoides farinae ( D. farinae ) drops for 1 year. The total nasal...

... (HFD). Mice were intranasally sensitized and challenged with house dust mites (HDMs) and were orally administered EM900. Airway inflammation was assessed using inflammatory cells in bronchoalveolar lavage (BALF). Cytokines were examined by ELISA in lung tissues. Lung interstitial macrophages (CD45...

...Hao Chen; Zhifeng Huang; Wenting Luo; Wanjia Li; Peiyan Zheng; Haisheng Hu; Baoqing Sun Introduction: The impact of furry animal allergens on house dust mite (HDM)-induced allergic rhinitis (AR) is unclear. Objective: We aimed to investigate the co-sensitization and cross-sensitization of furry...

... was to investigate the efficacy and safety of increasing SLIT dosage at 6 months in patients with house dust mite-induced allergic rhinitis (AR) who had low response to treatment. Methods: A total of 157 AR participants aged 4–60 years were enrolled and received SLIT with Dermatophagoides farinae drops. After 6...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Proteomics House dust mite Inbreeding Allergens Blomia tropicalis Experimental Allergy Research Article Int Arch Allergy Immunol 2019;180:159 172 DOI: 10.1159...

...Cong Wang; Luo Wang; Ban-Cheng Chen; Hao Yu; Lu Li; Kao-Yuan Zhang; Bo Yu; Zhun Wei; Xiao-Fan Chen Allergic diseases affect more than 25% of the global population. Der p 2 is the major allergen of the house dust mite (HDM) Dermatophagoides pteronyssinus . Allergen-specific immunotherapy is the only...

... exacerbated in SCD mice when they are exposed to the human allergen, house dust mite (HDM). Methods and Results: Eosinophil counts in bronchoalveolar lavage fluid were determined by cytocentrifugation and increased in both wild-type (WT) and SCD mice after acute exposure to a high dose (25 µg) of HDM, which...

...Yutaka Ueda; Kazuyuki Nakagome; Takehito Kobayashi; Toru Noguchi; Tomoyuki Soma; Katsuyo Ohashi-Doi; Kenichi Tokuyama; Makoto Nagata Background: Even in subjects who are not sensitized to house dust mite (HDM), allergic symptoms can be aggravated by exposure to dust, suggesting that innate immune...

... , and Der f 5 from D. farinae . Methods: We collected serum from 60 house dust mite (HDM)-allergic patients residing in the Dellys area of Boumerdès province in northern Algeria. The presence of specific IgE to Der p 5, Der f 5, and Blo t 5 was analyzed. We performed in silico analysis of the structure...

... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. House dust mite Genome Dermatophagoides pteronyssinus...