...Philipp Cesana; Kathrin Scherer; Andreas J. Bircher Immediate type hypersensitivity reactions due to heparins are rare, and the exact immunologic pathomechanism has not been identified so far. In our 2 case reports, we describe first a 50-year-old female who received dalteparin (Fragmin®...

... heparin was chosen is that these drugs do not need a regular monitoring of coagulation parameters. Among low molecular weight heparins, nadroparin was chosen as anticoagulant treatment because it is available in a formulation which allows a single administration each day. Tranexamic acid...

...William M. Abraham; Michael K. Abraham; Tahir Ahmed Our previous studies have shown that heparin, a competitive inhibitor of inositol triphosphate receptors, inhibits airway anaphylaxis in vivo. In the present study, we tested the hypothesis that heparin blocks immunologically induced tracheal...

...Helene Ruth Su; Robert J. Boackle Using normal human serum and EDTA-plasma as the two sources of S-protein (vitronectin) in an enzyme-linked immunosorbent assay, we determined that heparin pretreatment of immobilized rgp120 or of immobilized CD4 caused the serum form of S-protein to deposit...

..., instructions or products referred to in the content or advertisements. Mast cells Heparin Jejunum Mongolian gerbils Nippostrongylus brasiliensis Y. Horii N. Ishikawa Y Nawa Department of Parasitology, Miyazaki Medical College, Japan Original Paper Int Arch Allergy Immunol 1992;98:415-419 Heparin...

...Oliver Noga; Tilo Brunnée; Christoph Schäper; Gert Kunkel Background: In a recent study mast cell heparin proteoglycan (HepPG) of a cell line derived from a mouse mastocytoma was isolated. Glycosaminoglycans proved to be an initiating surface for starting contact activation and could explain kinin...

.... Charles R, Edwards BF: A model of the platelet factor 4 complex with heparin. Proteins Struct, Funct and Genet 1992;14:277–287. 7. Luscombe M, Marshall SE, Pepper DR, Holbrook JJ: Multivalent proteins and multidentate polysaccharides: Interaction of platelet–factor–4 and heparin. Biochem Soc Transact...

... fibrinolysis, is discussed. Thus, accumulating evidence exists that human MC express and release the tissue-type plasminogen activator (tPA) in a constitutive manner. MC also express the urokinase receptor (uPAR) and heparin. Most importantly, however, MC lack plasminogen activator inhibitors (PAI-1, PAI-2...