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Keywords: FIP1L1/PDGFRα
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Journal Articles
Int Arch Allergy Immunol (2010) 152 (Suppl. 1): 101–105.
Published Online: 04 June 2010
.... As a result, a new category, ‘myeloid and lymphoid neoplasm with eosinophilia and abnormalities in PDGFRA, PDGFRB or FGFR1’, has recently been added to the new WHO criteria for myeloid neoplasms. FIP1L1/PDGFRα-positive disorders are characterized by clonal hypereosinophilia, multiple organ dysfunctions due...
Journal Articles
Int Arch Allergy Immunol (2009) 149 (Suppl. 1): 102–107.
Published Online: 03 June 2009
... induced by FIP1L1/PDGFRα in cell lines, bone marrow mast cells, primary human eosinophils and in murine myeloproliferative disorder models. In this review, we introduce the current knowledge on the relationship between FIP1L1/PDGFRα and cell signaling, eosinophil proliferation, survival and activation...