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1-20 of 158
Keywords: Eosinophil
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Journal Articles
Subject Area:
Immunology and Allergy
Jing Guo, Jianwei Wang, Xinjun Xu, Yujuan Yang, Pengyi Yu, Zhen Liu, Jiayu Cao, Qintai Yang, Yu Zhang, Xicheng Song
Int Arch Allergy Immunol (2023) 184 (11): 1099–1105.
Published Online: 18 August 2023
... (65.85%) than in patients without asthma (9.17%). With regard to specific airway function indicators, age and a patient’s blood eosinophil (%) were identified as independent risk factors for lower FEF 50% %pred and FEF 25–75% pred, with age being an independent risk factor for FEF 75% %pred in asthmatic...
Journal Articles
Subject Area:
Immunology and Allergy
Int Arch Allergy Immunol (2023) 184 (6): 576–586.
Published Online: 13 June 2023
...Ling Ma; Yunping Deng; Kanghua Wang; Jianbo Shi; Yueqi Sun Introduction: Chronic rhinosinusitis with nasal polyps (CRSwNPs) in China is characterized by a mixed eosinophilic-neutrophilic inflammation, linking to a more heterogeneous clinical phenotype. However, the relationship between eosinophilic...
Journal Articles
Subject Area:
Immunology and Allergy
Int Arch Allergy Immunol (2022) 183 (9): 946–952.
Published Online: 06 September 2022
... and detected SERPINB10 levels in induced sputum by ELISA and analyzed the correlation between SERPINB10 expression levels and FeNO, eosinophils in peripheral blood, lung function, and Th2 cytokines (IL-4, IL-5, and IL-13). Results: The levels of SERPINB10 in induced sputum in asthmatic patients were higher...
Journal Articles
Subject Area:
Immunology and Allergy
Int Arch Allergy Immunol (2022) 183 (11): 1209–1215.
Published Online: 25 August 2022
... = 0.026), eosinophil count (median = 190 [0–800] [cells/µL], p < 0.001), basophil count (median = 40 [0–100] [cells/µL], p = 0.021), and total IgE (median = 240.5 [45–2,644] [kU/L], p < 0.001) level were significantly higher in the omalizumab responder patients (UCT score ≥12 at 6 months...
Journal Articles
Subject Area:
Immunology and Allergy
Int Arch Allergy Immunol (2022) 183 (8): 835–842.
Published Online: 21 March 2022
...Jinbo Han; Weiqing Wang; Zhenzhen Zhu; Lei Wang; Yujie Chen; Ruiqi Wang; Kai Guan; Wei Lv Introduction: Eosinophilic chronic rhinosinusitis with nasal polyps (eCRSwNP) exhibits a poorer prognosis than noneCRSwNP. The aim of this study was to analyze the potential of total immunoglobulin E (tIgE...
Journal Articles
Subject Area:
Immunology and Allergy
Int Arch Allergy Immunol (2021) 182 (10): 962–970.
Published Online: 28 April 2021
...Yara Zoabi; Fidan Rahimli Alekberli; Yael Minai-Fleminger; Ron Eliashar; Francesca Levi-Schaffer Introduction: The pathogenesis of chronic rhinosinusitis (CRS) with nasal polyps (CRSwNPs) is not yet completely understood. Based on current knowledge, the infiltration of mast cells and eosinophils...
Journal Articles
Subject Area:
Immunology and Allergy
Int Arch Allergy Immunol (2021) 182 (1): 65–75.
Published Online: 14 September 2020
... with different CLC concentrations. Results: Sixty-eight (62.96%) patients developed recurrence during a 12- to 33-month postoperative follow-up. CLC concentrations in nasal secretions were positively correlated with eosinophil percent in polyp tissue and peripheral blood and were significantly higher in patients...
Journal Articles
Subject Area:
Immunology and Allergy
Int Arch Allergy Immunol (2020) 181 (10): 765–773.
Published Online: 21 July 2020
...Jiayi Yang; Jinjin Fan; Li Fan; Chunyan Yi; Jianxiong Lin; Haiping Mao; Xiao Yang; Xin Wang Introduction: Eosinophilia (eosinophil fraction of leukocytes >5%), an indicative parameter for bioincompatibility in various circumstances, is well established in hemodialysis. However, change...
Journal Articles
Subject Area:
Immunology and Allergy
Int Arch Allergy Immunol (2020) 181 (11): 853–861.
Published Online: 20 July 2020
...Hao Lv; Pei-Qiang Liu; Rong Xiang; Wei Zhang; Shi-Ming Chen; Yong-Gang Kong; Yu Xu Background: A hallmark of eosinophilic chronic rhinosinusitis with nasal polyps (eCRSwNP) is mucosal eosinophil-predominant inflammation. Nasal nitric oxide (nNO) is a known biomarker of eosinophilic inflammation...
Journal Articles
Int Arch Allergy Immunol (2020) 181 (8): 624–628.
Published Online: 16 June 2020
...-induced eosinophilic lung disease and eosinophil-associated Th2 immunopotentiation following infection after vaccination. Here, we review the anticipated characteristics of a COVID-19 vaccine to avoid vaccine-associated eosinophil immunopathology. hans-uwe.simon@pki.unibe.ch 8 06 2020 8...
Journal Articles
Subject Area:
Immunology and Allergy
Eric Tyrell Oliver, Kris Chichester, Kelly Devine, Patricia Meghan Sterba, Craig Wegner, Becky Marie Vonakis, Sarbjit Singh Saini
Int Arch Allergy Immunol (2019) 179 (1): 21–30.
Published Online: 15 March 2019
.... Secondary objectives included the effects of AZD1981 on prostaglandin D 2 (PGD 2 )-induced eosinophil shape change, circulating leukocyte subsets, CRTh2 expression on blood leukocytes, and total blood leukocyte histamine content. Results: Twenty-eight subjects were randomized to AZD1981 or placebo, with 26...
Journal Articles
Subject Area:
Immunology and Allergy
Int Arch Allergy Immunol (2018) 177 (1): 16–28.
Published Online: 07 June 2018
...Mats W. Johansson; Elizabeth A. Kelly; Christopher L. Nguyen; Nizar N. Jarjour; Bruce S. Bochner Background: Siglec-8 is present at a high level on human blood eosinophils and low level on blood basophils. Engagement of Siglec-8 on blood eosinophils causes its internalization and results in death...
Journal Articles
Subject Area:
Immunology and Allergy
Esra Birben, Umit M. Sahiner, Cagatay Karaaslan, Tolga S. Yavuz, Erdal Cosgun, Omer Kalayci, Cansin Sackesen
Int Arch Allergy Immunol (2014) 163 (3): 185–192.
Published Online: 13 February 2014
.... the rs3806933 CC genotype with asthma in boys (p = 0.032, nonsignificant after multiple testing) and the rs2289276 CC genotype with higher eosinophil numbers in asthmatic girls (p = 0.003). The presence of allergic rhinitis in asthmatic children strengthened the association of the rs11466749 GG genotype...
Journal Articles
Subject Area:
Immunology and Allergy
Akiko Kawashima, Tomoko Suzuki, Fuyumi Nishihara, Takehito Kobayashi, Yotaro Takaku, Kazuyuki Nakagome, Tomoyuki Soma, Koichi Hagiwara, Minoru Kanazawa, Makoto Nagata
Int Arch Allergy Immunol (2013) 161 (Suppl. 2): 10–15.
Published Online: 29 May 2013
... that have migrated in response to interleukin-8 (IL-8) may lead eosinophils to accumulate in the airways of patients with asthma and possibly aggravate the disease. In this study, we investigated whether formoterol modified the trans-basement membrane migration (TBM) of eosinophils stimulated...
Journal Articles
Subject Area:
Immunology and Allergy
Andrew G. Ayars, Leonard C. Altman, Sue Potter-Perigo, Katherine Radford, Thomas N. Wight, Parameswaran Nair
Int Arch Allergy Immunol (2013) 161 (1): 65–73.
Published Online: 14 December 2012
...-controlled study. We measured hyaluronan and versican levels by enzyme-linked immunosorbent assay in sputum collected before and after the 16-week treatment phase. Patients underwent a predefined prednisone tapering schedule if they remained exacerbation free, and sputum eosinophil percentage, asthma control...
Journal Articles
Subject Area:
Immunology and Allergy
Int Arch Allergy Immunol (2012) 159 (2): 157–161.
Published Online: 31 May 2012
...Young-Sin Song; Eun-Mi Yang; Seung-Hyun Kim; Hyun Jung Jin; Hae-Sim Park Background: Aspirin-exacerbated respiratory disease (AERD) is a clinical syndrome associated with chronic inflammation in the airways coincident with chronic rhinitis, sinusitis, recurrent polyposis and asthma. Eosinophils...
Journal Articles
Subject Area:
Immunology and Allergy
Osamu Kaminuma, Hisako Fujimura, Keiko Fushimi, Koji Ogawa, Aya Nakata, Hideo Kikkawa, Hirokazu Okudaira, Akio Mori
Int Arch Allergy Immunol (2001) 124 (1-3): 287–289.
Published Online: 24 January 2012
...Osamu Kaminuma; Hisako Fujimura; Keiko Fushimi; Koji Ogawa; Aya Nakata; Hideo Kikkawa; Hirokazu Okudaira; Akio Mori Background: The crucial role of T helper (Th) 2 cells in allergic eosinophilic inflammation has been established. Methods: To determine the dynamics of Th2 cells in airway...
Journal Articles
Subject Area:
Immunology and Allergy
Int Arch Allergy Immunol (2001) 124 (1-3): 230–232.
Published Online: 24 January 2012
.... Akdis M, Trautmann A, Blaser K, Akdis CA: Life span of skin homing T cells in atopic dermatitis: Survival in skin, activation induced apoptosis in peripheral blood. J Allergy Clin Immunol 2000;105:167 (abstr.). 12. Simon H-U, Blaser K: Inhibition of programmed eosinophil death: A key pathogenic...
Journal Articles
Subject Area:
Immunology and Allergy
Int Arch Allergy Immunol (2001) 124 (1-3): 172–175.
Published Online: 24 January 2012
...Akio Mori; Hirokazu Okudaira; Noriaki Kobayashi; Kazuo Akiyama Background: Helper T cells are involved in chronic eosinophilic inflammation. Control of cytokine production seems to be an effective management. Methods: The effect of nonactin, SB203580, a p38 MAP kinase inhibitor, and JTE-711...
Journal Articles
Subject Area:
Immunology and Allergy
Int Arch Allergy Immunol (2001) 124 (1-3): 365–366.
Published Online: 24 January 2012
... free calcium concentration ([Ca 2+ ]i) in human eosinophils. In this study, we have examined the effect of seratrodast on eosinophil cationic protein (ECP) release and changes of [Ca 2+ ]i in human eosinophils induced by PGD 2 . Methods: Eosinophils from healthy donors were incubated with or without IL...
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