... allergy in children with a history of suspected mild cutaneous reactions with BLs. Beta-lactam (BL) antibiotics, especially penicillin and cephalosporins, are the most commonly prescribed drugs in the pediatric population and the most common cause of drug hypersensitivity reactions in these age groups...

..., instructions or products referred to in the content or advertisements. Eosinophil-to-lymphocyte ratio Neutrophil-to-lymphocyte ratio Platelet-to-lymphocyte ratio Nonsteroidal anti-inflammatory drugs Drug hypersensitivity Nonsteroidal anti-inflammatory drugs (NSAIDs) have high analgesic, anti...

..., and angioedema, and drug hypersensitivity reactions. These can affect patients’ quality of life and can generate high costs for health care. Epidemiological studies have provided evidence for changing patterns of allergic diseases caused by lifestyle and climate changes which have consequences for medical care...

... on recent insights in the pathogenesis of food allergy and drug hypersensitivity, novel strategies for diagnostics, allergen avoidance, and induction of tolerance have been developed. Here, we summarize important findings in the field of clinical allergy and immunology with a special focus on asthma...

... suggested that the incidence may be much lower during EBV infection. There are no clear data on the incidence of true drug hypersensitivity among these patients. The aim of this study is to determine the incidence of rash and antibiotic allergy after antibiotic treatment in children with EBV infection...

...Werner J. Pichler; Yuttana Srinoulprasert; James Yun; Oliver Hausmann Multiple drug hypersensitivity (MDH) is a syndrome that develops as a consequence of massive T-cell stimulations and is characterized by long-lasting drug hypersensitivity reactions (DHR) to different drugs. The initial symptoms...

..., quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Biologics Hypersensitivity Drug hypersensitivity Rapid drug desensitization...

...) are among the most common causes of drug hypersensitivity (HS) reactions. The diagnosis is based on a careful clinical history, and provocation tests are considered the gold standard for diagnosis. Skin tests have some value to study reactions to pyrazolones. Laboratory investigations are mostly used...

...Werner J. Pichler; Oliver Hausmann Drug hypersensitivity reactions (DHR) are clinically and functionally heterogeneous. Different subclassifications based on timing of symptom appearance or type of immune mechanism have been proposed. Here, we show that the mode of action of drugs leading to immune...

...Ozlem Cavkaytar; Ebru Arik Yilmaz; Betul Karaatmaca; Betul Buyuktiryaki; Cansın Sackesen; Bulent E. Sekerel; Ozge Soyer Background: Although non-steroidal anti-inflammatory drug hypersensitivity (NSAID-H) has been widely studied in adults, there is still a lack of data regarding the features...

...Yuttana Srinoulprasert; Werner J. Pichler Background: The lymphocyte transformation test (LTT) is used for in vitro diagnosis of drug hypersensitivity reactions. While its specificity is over 90%, sensitivity is limited and depends on the type of reaction, drug and possibly time interval between...

...Silvia Caimmi; Davide Caimmi; Philippe-Jean Bousquet; Pascal Demoly Background: Hypersensitivity to nonsteroidal anti-inflammatory drugs (NSAIDs) is one of the most common drug hypersensitivities. Several clinical subtypes have been distinguished depending on symptomatology (respiratory, cutaneous...

... advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2011 Drug allergy Drug hypersensitivity...

...Sharon Reisfeld; Arnon Goldberg; Ronit Confino-Cohen Background: Drug hypersensitivity (DH) is potentially life threatening. Its management in the emergency department (ED) is not always satisfactory. Previous studies have evaluated the management of allergic reactions in the ED, but none has...

... a Department o f Dermatology, School of Medicine, Fukuoka University, and b Department of Dermatology. Faculty o f Medicine, Kyushu University, Fukuoka, and c Mitsubishi Kagaku Bio-Clinical Laboratories, Tokyo. Japan Key Words Diagnosis in vitro Sulfidoleukotricnes Drug hypersensitivity Nonsteroidal anti...

... advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Desensitization Drug hypersensitivity...