...Sara López-Freire; Margarita Armisén; María Jesús Cruz; Carmen Vidal Introduction: Changes in the cytokine profile from type 2 to type 1 together with the induction of regulatory cells are expected during hymenoptera venom immunotherapy (VIT). The present study was aimed to investigate the changes...

...Xuying Liu; Siyu Sun; Dongyan Liu The interleukin-17 (IL-17) family is a relatively new family of cytokines consisting of 6 related factors (IL-17A–IL-17F), while the receptor family consists of 5 members: IL-17RA–IL-17RE. IL-17A is the prototype member of this family, which is also the signature...

... of the Janus kinase-signal transducer and activator of transcription (JAK-STAT) pathway in AT1-R expressed on peripheral tissues and cytokine receptors on the surface of immune cells, potential targeting of this pathway using JAK inhibitors (JAKinibs) is suggested as a promising approach in patients with COVID...

... of bacterial infections on bronchial asthma, we examined pharyngeal bacterial colonization, duration of wheezing, and serum levels of cytokines and chemokines during acute exacerbations of asthma in children. Methods: Potential bacterial pathogens were investigated in pharyngeal samples and viruses obtained...

... by hypothermia shock response (HSR). Mucosal mast cell degranulation was measured by the elevation of mMCP-1 in the blood. The mice were monitored for dermatitis. Skin tissues were used in histopathology and for measuring cytokine/chemokine/adhesion molecule levels using a protein microarray system. Results...

... inflammatory proteins which can serve as biomarkers for ACD. Methods: We measured levels of 102 cytokines, chemokines, and growth factors in the sera of 16 ACD patients during acute and remission phases, and 16 healthy volunteers. Results: Serum levels of adiponectin, chemokine (C-C motif) ligand 5 (CCL5), C...

...Shingo Ochiai; Naoki Shimojo; Yoshinori Morita; Minako Tomiita; Takayasu Arima; Yuzaburo Inoue; Mayuko Nakaya; Naoki Uehara; Yasunori Sato; Chisato Mori; Yoichi Suzuki; Yoichi Kohno Background: A few studies have reported that the quantity of selected cytokines/chemokines in breast milk might...

... the association of house dust microbial content with cytokine-producing capacity at birth and at the age of 1 year. Methods: Production of TNF-α, IFN-γ, IL-5, IL-8 and IL-10 at birth (n = 228) and at the age of 1 year (n = 200) following 24- and 48-hour whole-blood stimulation with staphylococcal enterotoxin B...

..., quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Diesel Particulate Pollution Cytokine Airway inflammation Asthma Chemokine...

...Akio Mori; Hirokazu Okudaira; Noriaki Kobayashi; Kazuo Akiyama Background: Helper T cells are involved in chronic eosinophilic inflammation. Control of cytokine production seems to be an effective management. Methods: The effect of nonactin, SB203580, a p38 MAP kinase inhibitor, and JTE-711...

... with asthma and 9 non-atopic individuals. Cells were activated as Th0 and differentiated into Th2 cells. The effect of AZM on activated CD4+ cells was evaluated with respective cell proliferation and cytokine production. Results: Th0 and Th2 CD4+ T cells from atopic asthmatic children produced greater...

... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2010 Respiratory syncytial virus Th1 Th2 Cytokine CCL2 Acute bronchiolitis is a distressing, potentially life-threatening respiratory condition in infancy. The majority...

... in SLE patients and the involvement of cytokines in this immune response. Methods: Sera from 92 SLE patients and 68 healthy controls were evaluated for the presence of antinuclear IgE antibodies by immunoperoxidase with HEp-2,000® cells and immunoblotting with IgG-depleted sera. Total IgE, IgE specific...

... symptoms. Previously, omalizumab was shown to cause a dramatic and reversible loss of cell surface high-affinity IgE receptors, FcΕRI, from the peripheral blood basophils of asthmatics. The consequences of receptor loss for the FcΕRI-mediated synthesis and release of cytokines implicated in allergic asthma...

...K. Saneyoshi; O. Nohara; T. Imai; F. Shiraishi; H. Moriyama; H. Fujimaki To examine the potential effects of environmental pollutants on the production of cytokines in mast cells, mouse bone marrow-derived mast cells (BMMC) were cultured at various concentrations of diesel exhaust particulates (DEP...

...Koichi Kuribayashi; Masayuki Tsukiyama; Torn Takenaka The expression of cytokine mRNAs in mice during immune deviation was examined. A subcutaneous injection of antigen-pulsed dendritic cells (DCs) induced strong delayed-type hypersensitivity (DTH) but not humoral immunity, but an intravenous...

...Shin-ichi Konno; Yoshiki Gonokami; Masatsugu Kurokawa; Kenta Kawazu; Kazuhito Asano; Ken-ichi Okamoto; Mitsuru Adachi To examine whether levels of inflammatory cytokines and eosinophil cationic protein (ECP) in the sputum reflect the severity of bronchial asthma, we measured their levels...

...Philippe Paquet; Gérald E. Piérard Interleukin-6 is a pleiotropic cytokine with numerous biological activities. It is produced by normal constituents of the skin, including epidermal cells, fibroblasts and dermal endothelial cells. It is also synthesized by inflammatory cells infiltrating the skin...

... dermatitis, who are positive for IgE antibodies to OVA and clinically allergic to hen egg, and characterized them for their cytokine production pattern. All TCLs we could study were mainly composed of CD4+ T cells. Most TCLs produced significant amounts of interleukin 4 (IL-4) and IL-5 but no or very little...

... secrete both fíbroblast-activating cytokines and IgM and thus they likely play an important role as effector cells in the development of dermal fíbrosis and autoantibodies in this avian model of scleroderma. Original Paper Int Arch Allergy Immunol 1995;107:519-526 Matthew R. Duncana Brian Berman1' Judy...