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Keywords: Chronic eosinophilic leukemia
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Journal Articles
Subject Area:
Immunology and Allergy
Int Arch Allergy Immunol (2010) 152 (Suppl. 1): 101–105.
Published Online: 04 June 2010
...Yoshiyuki Yamada; Jose A. Cancelas Since the identification of the FIP1L1/PDGFRA fusion gene as a pathogenic cause of the hypereosinophilic syndrome (HES), the importance of the molecular classification of HES leading to the diagnosis of chronic eosinophilic leukemia (CEL) has been recognized...
Journal Articles
Subject Area:
Immunology and Allergy
Int Arch Allergy Immunol (2009) 149 (Suppl. 1): 102–107.
Published Online: 03 June 2009
... that distinguish chronic eosinophilic leukemia (CEL) from HES. As such, the fusion gene FIP1L1/PDGFRA was found as a cause of CEL in a significant proportion of patients initially diagnosed as having HES. Several investigations have tried to dissect the mechanism of leukemogenesis; eosinophilia and signaling...
