... for allergic asthma, models that are relevant to human disease are needed. Methods: Female BALB/c mice were presensitised subcutaneously with alum-adsorbed recombinant cat allergen Fel d 1, followed by intranasal challenges with cat dander extract spiked with recombinant Fel d 1 for 7 weeks. For reference...

... that for mite exposure and sensitization is linear, is highly relevant to understanding the role of allergens in the increase in allergic disease. Modified Th2 Cat allergen Mite Asthma Tolerance © 2001 S. Karger AG, Basel 2001 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved...

... is currently based on cat dander extract. As allergen extracts from natural sources are heterogeneous in composition, the allergen content may vary. With the introduction of allergens produced by recombinant techniques, a large panel of recombinant allergenic molecules including the major cat allergen...

... Service and Laboratory for Experimental and Clinical Immunology, University of Amsterdam, The Netherlands Structure of the Major Cat Allergen Fel d I in Different Allergen Sources: An Immunoblotting Analysis with Monoclonal Antibodies against Denatured Fel d I and Human IgE Key Words Cat allergen Feld 1...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Cat allergen Allergen-specific immunotherapy Th1/Th2 balance Vaccination For antibody detection, 96-well microtitre plates (Nunc Maxisorb, Basel, Switzerland) were...

... in the children’s homes and assayed for the cat allergen Fel d 1 and the dog allergen Can f 1 before randomization at day 0, and after 6 and 12 months. The collection of the dust samples was done by the homeowners themselves, using a new disposable vacuum cleaner bag for each sample. Mattress dust samples were...

... on the development and maintenance of allergic disease in humans and on markers of allergic inflammation in animal models of allergy. In this study, we investigated the effect of low concentrations of LPS on human peripheral blood mononuclear cells (PBMC) stimulated with the major cat allergen Fel d 1. Methods...

...Gennaro Liccardi; Domingo Barber; Maria Russo; Maria D’Amato; Gennaro D’Amato Background: Cat allergens are ubiquitous because the clothing of cat owners constitutes an important source of distribution of Fel d 1 in cat-free environments. Since Fel d 1 can adhere to a variety of surfaces, we sought...

.... Moreover, it is likely that modern energy-saving systems and the wide use of upholstered furniture has resulted in closer contact between cats (and their allergens) and humans. Many different methods have been developed to quantify the main cat allergen (Fel d 1) in settled dust and in ambient air...

... of cat allergens, not inducing asthma symptoms, could affect eosinophil cationic protein (ECP) levels in bronchoalveolar lavage (BAL) or in peripheral blood, without the appearance of clinical symptoms. Twelve patients with mild asthma, all sensitized to cats and not exposed to cat allergen at home...