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Keywords: Basophils
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Journal Articles
Journal Articles
Int Arch Allergy Immunol (2021) 182 (10): 917–931.
Published Online: 29 April 2021
... pathways discovered in recent years on urticaria, including the cell adhesion/chemotaxis pathway, interleukin (IL)-6/Janus tyrosine kinase/STAT pathway, IL-17/IL-23 pathway, basophil- and mast cell-related pathway, coagulation/fibrinolysis-related pathways, single-nucleotide polymorphism, and some other...
Journal Articles
Int Arch Allergy Immunol (2019) 179 (1): 21–30.
Published Online: 15 March 2019
... change. CRTh2 surface expression rose significantly on blood basophils during active treatment. No serious adverse events were observed. Conclusions: This is the first study to examine the efficacy of a CRTh2 antagonist in antihistamine-refractory CSU. AZD1981 treatment was well tolerated, effectively...
Journal Articles
Journal Articles
Int Arch Allergy Immunol (2017) 171 (3-4): 158–165.
Published Online: 14 December 2016
..., significant challenges remain in the fight against HIV. In particular, how uninfected cells capture HIV and transmit virions to target cells remains an unanswered question. Tissue mast cells and peripheral blood basophils can be exposed to virions or HIV products during infection. Several HIV proteins (i.e...
Journal Articles
Journal Articles
Int Arch Allergy Immunol (2016) 169 (1): 1–12.
Published Online: 09 March 2016
...Bernhard Kratzer; Winfried F. Pickl This review highlights the recent key advances in the biology of CD4 + effector T cells, antigen-presenting cells, Th17 and T regulatory cells, as well as immediate effector cells, such as mast cells, basophils and eosinophils, which are critically contributing...
Journal Articles
Journal Articles
Int Arch Allergy Immunol (2014) 164 (4): 271–279.
Published Online: 09 September 2014
...Barbara Dema; Ryo Suzuki; Juan Rivera Immunoglobulin E (IgE) and its high-affinity receptor (FcεRI) are well-known participants in the allergic response. The interaction of allergens with FcεRI-bound IgE antibodies is an essential step in mast cell/basophil activation and the subsequent release...
Journal Articles
Int Arch Allergy Immunol (2014) 164 (1): 27–29.
Published Online: 13 May 2014
...Yusuke Tanaka; Yuko Nakase; Masao Yamaguchi; Naoya Sugimoto; Kenshin Ohara; Hiroyuki Nagase; Ken Ohta We describe a case of formaldehyde-induced urticaria with a positive test result for serum IgE antibody against this substance. Formaldehyde's slow protein-binding property may explain why basophil...
Journal Articles
Int Arch Allergy Immunol (2013) 161 (1): 87–90.
Published Online: 15 December 2012
...A. Nopp; L.O. Cardell; S.G.O. Johansson Background: A reproducible standard for a graded allergen response in allergic rhinitis is lacking. The aim was to evaluate basophil allergen threshold sensitivity, CD-sens, as a diagnostic complement to nasal allergen challenge. Methods: Twenty-six patients...
Journal Articles
Journal Articles
Journal Articles
Int Arch Allergy Immunol (2001) 124 (1-3): 146–150.
Published Online: 24 January 2012
... mast cells in the various human tissues examined were tryptase-chymase double-positive. Conclusions: These results indicate that CCR3 is expressed on human mast cells and that these cells are attracted by CCR3-binding chemokines. 24 1 2012 Basophils CCR3 Chemotaxis Histamine Mast cells...
Journal Articles
Int Arch Allergy Immunol (2011) 155 (Suppl. 1): 64–70.
Published Online: 01 June 2011
...Kaiyu Han; Maho Suzukawa; Masao Yamaguchi; Naoya Sugimoto; Yuko Nakase; Takako Toda; Hiroyuki Nagase; Ken Ohta Background: Basophils are thought to play pivotal roles in the pathogenesis of allergic reactions, but their roles in inflammation associated with systemic abnormalities such as metabolic...
Journal Articles
Int Arch Allergy Immunol (2011) 156 (1): 16–26.
Published Online: 29 March 2011
...Francesca Gasparrini; Rosa Molfetta; Angela Santoni; Rossella Paolini The binding of IgE to high-affinity IgE receptors (FcΕRI) expressed on the surface of mast cells and basophils initiates a cascade of signaling events that results in the release of a wide array of proinflammatory mediators...
Journal Articles
Int Arch Allergy Immunol (2010) 153 (4): 323–334.
Published Online: 17 June 2010
...Gitte Lund; Henrik Jacobi; Per Stahl Skov; Jens Holm; Kaare Lund Background: Allergen-specific immunotherapy (SIT) leads to reduced symptoms upon allergen exposure through as yet unresolved mechanisms. Desensitization of basophils to specific allergens during the updosing phase of injection...
Journal Articles
Int Arch Allergy Immunol (2010) 151 (4): 318–330.
Published Online: 22 October 2009
... immunologic, biochemical and molecular biology procedures. Results: SV-IV-induced histamine release from human basophils and lung mast cells without any influence on leukotriene C 4 release and cell migration. The histamine release rate was slower compared with that induced by anti-IgE, the temperature...
Journal Articles
Journal Articles
Int Arch Allergy Immunol (2010) 151 (2): 89–97.
Published Online: 15 September 2009
...E. Crivellato; L. Travan; D. Ribatti Mast cells and basophils are granulated metachromatic cells which possess complex and partially overlapping roles in acquired and innate immunity, including both effector and regulatory activities. Mast cells and basophils cooperate in exacerbating...