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Keywords: Apoptosis
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Journal Articles
Int Arch Allergy Immunol (2023) 184 (10): 1056–1070.
Published Online: 21 June 2023
... apoptosis, and Western blotting was used to determine the levels of apoptotic-related proteins (cleaved caspase 3, cleaved polyadenosine-diphosphate-ribose polymerase) and HMGB1, TLR4, and MyD88. Enzyme-linked immunosorbent assay was used to assess the inflammatory response. Hematoxylin-eosin staining...
Journal Articles
Journal Articles
Int Arch Allergy Immunol (2018) 175 (1-2): 5–15.
Published Online: 06 January 2018
... from any ideas, methods, instructions or products referred to in the content or advertisements. Siglec-9 Siglec-E Severe asthma Neutrophils Programmed cell death Apoptosis Intravenous immunoglobulin Asthma is a chronic respiratory disease that affects more than 235 million people...
Journal Articles
Int Arch Allergy Immunol (2016) 171 (2): 119–129.
Published Online: 01 December 2016
.... 1 b). So we demonstrated that calcitriol independently sustained the viability by reducing both apoptosis and necrosis in human blood-derived eosinophils for 24 h ex vivo, in the absence of an additional anti-apoptotic factor. Peripheral blood eosinophils from atopic donors were purified...
Journal Articles
Int Arch Allergy Immunol (2014) 164 (2): 140–146.
Published Online: 02 July 2014
..., instructions or products referred to in the content or advertisements. Fig. 1 A persistent source of antigens induces sustained T lymphocyte activation. These cells undergo apoptosis after completing their effector functions ( 1 ). Activated CD40L+ apoptotic T cells convey activation signals to DCs...
Journal Articles
Journal Articles
Int Arch Allergy Immunol (2001) 124 (1-3): 296–298.
Published Online: 24 January 2012
... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. T cell Cytokines IgE Eosinophils Apoptosis Atopic dermatitis...
Journal Articles
Int Arch Allergy Immunol (2001) 124 (1-3): 35–37.
Published Online: 24 January 2012
... receptor Antigen-presenting cells Apoptosis NF-kappa B Dendritic cells For decades, studies on FcεRI focused on effector cells of anaphylaxis such as mast cells and basophils. FcεRI on these cells is essential for immediate-type hypersensitivity reactions like allergic rhinitis, urticaria...
Journal Articles
Int Arch Allergy Immunol (2001) 124 (1-3): 259–261.
Published Online: 24 January 2012
... eosinophils, at the subepithelial region beneath the basement membrane of the airway. Apoptosis is a form of physiological cell death, through which the cellular contents including biologically active substances are kept in the cell membrane and are removed without their harmful effects. So, attempts were...
Journal Articles
Int Arch Allergy Immunol (2001) 124 (1-3): 230–232.
Published Online: 24 January 2012
...Axel Trautmann; Mübeccel Akdis; Sven Klunker; Kurt Blaser; Cezmi A. Akdis 24 1 2012 Apoptosis is a key event in a variety of physiological and pathological conditions [ 7 ]. Current studies on the role of apoptosis in the pathogenesis of various diseases are focused mainly...
Journal Articles
Int Arch Allergy Immunol (2011) 155 (Suppl. 1): 64–70.
Published Online: 01 June 2011
... of AGEs on various functions and markers of human basophils, including CD11b expression, apoptosis, degranulation, and cytokine production. Results: Flow cytometric analysis indicated that the level of the receptor for AGEs (RAGE) on the surface of freshly isolated basophils was very low but was clearly...
Journal Articles
Int Arch Allergy Immunol (2011) 156 (2): 179–186.
Published Online: 18 May 2011
... effect was observed in non-atopic controls except that AZM did inhibit IFN-γ production of their Th0 cells. AZM at a higher dose decreased cell viability by inhibiting CD4+ T cell proliferation and enhanced their apoptosis, an effect similarly observed in Th0 and Th2 cells, and did not differ between...
Journal Articles
Int Arch Allergy Immunol (2010) 153 (4): 413–418.
Published Online: 18 June 2010
... MCs and neutrophils were significantly greater in mice with CM than in control mice, and pimecrolimus treatment decreased the numbers of MCs but not neutrophils. Extensive apoptosis of cutaneous MCs was observed in pimecrolimus-treated mice. The cutaneous histamine level was elevated in the mice...
Journal Articles
Int Arch Allergy Immunol (2010) 152 (Suppl. 1): 2–8.
Published Online: 04 June 2010
...Kenji Matsumoto; Maki Terakawa; Shuhei Fukuda; Hirohisa Saito Background: Activation of cell surface CD30 by immobilized anti-CD30 monoclonal antibodies (mAbs) induces extremely rapid and intense apoptosis in human eosinophils in vitro. This anti-CD30 mAb-induced eosinophil apoptosis was inhibited...
Journal Articles
Int Arch Allergy Immunol (2010) 153 (3): 294–302.
Published Online: 20 May 2010
... eosinophilic pneumonia (AEP and CEP). Furthermore, the biological activities (chemotaxis and apoptosis) of Gal-9 were compared with those of eotaxin using interleukin-5-primed or -unprimed eosinophils. Results: The levels of Gal-9 and eotaxin in the BALF from patients with AEP and those with CEP were higher...
Journal Articles
Int Arch Allergy Immunol (1996) 111 (3): 230–237.
Published Online: 04 September 2009
...I. Rinner; P. Felsner; D. Hofer; A. Globerson; K. Schauenstein Unlike splenic or blood lymphocytes, rat thymocytes spontaneously undergo continuously increasing apoptosis during culture. In this study we characterized apoptotic thymus cells of rats according to cell size, nuclear dye binding...
Journal Articles
Int Arch Allergy Immunol (1995) 108 (Suppl. 1): 31–35.
Published Online: 04 September 2009
... inhibited DNA fragmentation of eosinophils in vitro. TGF-β reversed the effect of IL-5, indicating that TGF-β1 activates the pathway of apoptosis. TGF-β1 significantly suppressed eosinophil protein X release induced by IL-5. These results suggest that TGF-β1 may play a role in the modulation of allergic...
Journal Articles
Int Arch Allergy Immunol (1995) 106 (1): 3–7.
Published Online: 04 September 2009
...-10. T-cell inactivation mirrors induction of anergy, T-cell receptor downregulation, and that of CD2, CD4 and CD8 cell surface molecules, as well as of apoptosis. Two waves of apoptosis cripple the T-cell repertoire of superantigen-reactive T cells, an immediate one being induced within 24 h...
Journal Articles
Int Arch Allergy Immunol (1996) 110 (3): 238–243.
Published Online: 04 September 2009
...H. Lechner; M. Amort; M.-M. Steger; C. Maczek; B. Grubeck-Loebenstein CD95 (APO-1) is a member of the TNF/nerve growth factor receptor superfamily, which is expressed on the surface of different types of cells. Cross-linking of CD95 leads to the induction of apoptosis. This may be of importance...
Journal Articles
Int Arch Allergy Immunol (1997) 112 (1): 9–12.
Published Online: 04 September 2009
...Shida Yousefi; Kurt Blaser; Hans-Uwe Simon Inhibition of apoptosis in eosinophils by cytokines such as IL-5 and GM-CSF may play an important role in the pathogenesis of allergic and parasitic disorders. Recently, there has been some progress in the understanding of the signal transduction pathways...