... and predictors of treatment responses are largely lacking in the literature. This study evaluates antihistamine (AH) and omalizumab response rates in the most common CIndU subtypes and examines whether certain features can predict treatment responses. Methods: We retrospectively analyzed CU patients...

... to in the content or advertisements. 2024 Anaphylaxis Adrenaline Antihistamine Corticosteroids Prehospital system Emergency department Treatment Prognosis Anaphylaxis is a severe, life-threatening generalised hypersensitivity reaction [ 1 ]. The anaphylactic reaction can start with urticaria...

...) can improve disease management, help prevent unnecessary healthcare costs, and save time. In this study, we aimed to identify predictors of complete response to standard-dosed and higher than standard-dosed antihistamine treatments in patients with CSU. Methods: Medical records of 475 CSU patients...

... was to examine the efficacy of prophylactic treatment with an antihistamine for seasonal allergic rhinitis (SAR) using an environmental challenge chamber (ECC). Methods: The study was performed in a randomized double-blind manner with a 3-way crossover design. The subjects were 50 patients with SAR caused...

... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Fexofenadine HCl Chronic idiopathic urticaria Japanese patient Antihistamine Treatment Fexofenadine is a nonsedating antihistamine...

... of histamine H 1 receptor antagonist (antihistamine) have been developed and used for the treatment of allergic diseases, the influence of antihistamines on TARC and MDC production is not well understood. Objective: The present study was undertaken to examine the influence of antihistamines on TARC and MDC...

..., instructions or products referred to in the content or advertisements. Antihistamine Cetirizine Eosinophils Chemotaxis Allergy Original Paper Int Arch Allergy Immunol 1994;103:384-390 Chiharu Okada Ryosuke Eda Hidefumi Miyagawa Haruhito Sugiyama Russell J. Hopp Againdra K. Bewtra Robert G. Townley...

... the inhibitory activity of loratadine, indicating that external Ca 2+ and loratadine have antagonistic effects on basophil histamine release. These results indicate that loratadine, in addition to H 1 receptor blocking activity, has the capacity to inhibit histamine release from human basophils. Antihistamine...

...Sanjay N. Mandhane; Jigar H. Shah; Prashant C. Bahekar; Sameer V. Mehetre; Chandrashekhar A. Pawar; Ashish S. Bagad; Gajanan U. Chidrewar; Chitturi Trinadha Rao; Thennati Rajamannar Background: The anti-inflammatory potential of antihistamines has significant clinical utility. Long-term...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Antihistamine Chemotaxis Desloratadine Keratinocytes Loratadine Histamine H 1 -receptor antagonists have...

... levels in the peripheral blood but, to date, the possible effect of antihistamines on Eo/B progenitors has not been explored. Our objective was to evaluate whether the antihistamine desloratadine (DL) can modulate peripheral blood Eo/B progenitors or other markers of allergic inflammation. Methods: We...

...Ren-Long Wu; John C. Anthes; William Kreutner; Alan G. Harris; Robert E. West Jr Background: The human histamine H 1 receptor is constitutively active and exhibits basal activation of nuclear factor-ĸB (NF-ĸB), an important modulator of allergic inflammation. Certain H 1 antihistamines have...

... advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Antihistamine Asthma Desloratadine Efficacy...

... cells without impairing the immune system effectors. The possible clinical significance of these results are an antiallergic property and CD54 modulation on fibroblasts with a good safety profile as far as the lymphocyte response is concerned. Antihistamine CD54 Epithelial cell Fibroblast Nasal...

...J.P. Rihoux; L. Michel; R. Arnold; W. König Some recent clinical studies carried out with the potent H 1 –antihistamine cetirizine (CTZ) suggest that this drug could be useful for the treatment of mild to moderate asthma and even for the prevention of the disease. Besides a potent antagonism of H 1...

... responses. A compound which antagonizes both H 1 and NK-1 receptors, such as MDL 108,207DA, may present a significant therapeutic advantage over pure antihistamines. Methods: The binding affinity of MDL 108,207DA for H 1 and NK-1 receptors was evaluated and its potency of antagonism evaluated in vitro...