... to understand how EPIT inhibits allergic symptoms despite its resemblance to skin sensitization so it can be performed more effectively and safely. To understand the mechanism involved, it is important to develop an animal model to measure the effects of antigen application to skin on food allergy. tyoshi...

... of glucocorticoid treatment. Our study helped in understanding the contribution of miRNAs to the pathogenesis of asthma. Asthma Mimic or antagomir Inflammation Animal models Dexamethasone Asthma, also known as bronchial asthma, is a common airway inflammatory disease. The incidence of asthma...

... children. New IF compositions with improved prevention and treatment properties are needed, along with appropriate preclinical animal models, to evaluate these properties before introduction into humans. Objectives: We aimed to develop preclinical models for the assessment of the primary preventive...

.... Animal models Anti-asthma drugs Murine asthma models Respiratory diseases Asthma therapy Since the 1990s, there has been an explosion of scientific data on the pathophysiological mechanisms thought to play a role in asthma. Data have accumulated from experiments with congenic, gene-deficient...

.... Allergy vaccines Animal models Ara h 2 Peanut allergy Polylysine Regulatory T cells Peanut allergy, an epidemic allergic disease, is an adverse immunologic response to peanut allergens which is potentially life-threatening. It is estimated that 1.2-1.5% of individuals in Europe are affected...

... exacerbates the symptoms of Th2-type diseases, airway inflammation [ 12 ] and asthma [ 13 ]. In the gastrointestinal tract, treatment with an anti-TNF-α antibody enhances the number and function of Foxp3 + CD4 + CD25 + regulatory T cells in inflammatory bowel diseases [ 14 ]. In an animal model, the adoptive...

... Airway inflammation Airway wall remodelling Animal models Asthma Chronic allergen challenge Th17 cells Asthma is a chronic inflammatory disease of the airways associated with a variety of structural changes in the airway wall and hyper-responsiveness of the airways to bronchoconstrictor...

... or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Aging Animal models Inflammatory disorders Inflamm-aging Osteoporosis Since...

... from any ideas, methods, instructions or products referred to in the content or advertisements. Cysteine protease Cytokines Eosinophilia Intranasal administration Asthma model Allergic airway inflammation Animal models The major house dust mite allergen Der p 1, a typical peptidase...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Therapy Inhibition of inflammation B lymphocytes Allergic asthma Animal models Immunoglobulin E...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Serine proteases Mast cells Tryptase Asthma Animal models Clinical Features, Management and Pharmacology...

... or pathological conditions [ 14 ]. In the present study, we set out to examine the role of NOS-1-derived NO in an animal model of allergic airway inflammation using mice with a targeted NOS 1 gene deletion. In view of studies suggesting a role for NOS 1 in the pathogenesis of asthma, we wished to determine...

... into the draining lymph nodes. In this review article, we discuss the most recent findings from animal models of asthma, which highlight an essential role for these cells in the induction and maintenance of eosinophilic airway inflammation. This increasing knowledge might lead to the identification of new targets...