...Dayu Guan; Yijun Liu; Yue Gu; Bowen Zheng; Rong Sun; Yang Shen; Yucheng Yang Introduction: Allergic diseases are common clinical diseases. Although allergen-specific immunotherapy (AIT) and biologics have been widely recognized, the clinical efficacy, safety, advantages, and disadvantages...

...Fan Zhang; Yuan Qian; Jiashun Liao; Chuang Zhou; Wei Ren; Qiuzi Jin Background: Immunoglobulin E (IgE) plays a pivotal role in the pathogenesis of allergic diseases by engaging with FcεRI and FcεRII receptors, triggering allergic responses. The development of anti-IgE antibodies, such as omalizumab...

...Zengxiao Zhang; Gongfei Li; Shizhe Zhou; Minghui Wang; Longgang Yu; Yan Jiang Introduction: Asthma is associated with upper airway diseases and allergic diseases; however, the causal effects need to be investigated further. Thus, we performed this two-sample Mendelian randomization (MR) analysis...

...Ting-Yi Chiang; Hsiang-Ying Lee; Wei-Chen Chien; Hsiao-Chun Su; Yung-Chun Su; Chung-Wei Lin Introduction: Sexual dysfunction (SD) and allergic disease are common health concerns worldwide and bear a potential relationship. This scoping review is conducted to analyze the currently available data...

... system, and postnatal vitamin D insufficiency is one of the risk factors for the development of allergic disease. However, the effects of women’s vitamin D intake during pregnancy on the prevalence of allergic disease in their children remain controversial. Methods: From the Japan Environment...

... for the development of allergic diseases in children or whether social capital modifies the association. The objective of this study was to examine whether women’s experiences of such events during pregnancy were associated with the development of allergic diseases in their offspring at 3 years old and whether social...

...Reiji Kojima; Ryoji Shinohara; Megumi Kushima; Sayaka Horiuchi; Sanae Otawa; Hiroshi Yokomichi; Yuka Akiyama; Tadao Ooka; Kunio Miyake; Zentaro Yamagata; the Japan Environment and Children’s Study Group Background: Socioeconomic status has been found to be associated with allergic diseases...

... , Akdis   M , Bavbek   S , Bossios   A , et al.   Considerations on Biologicals for Patients with allergic disease in times of the COVID-19 pandemic: an EAACI Statement . [published online ahead of print, 2020 Jun 5] . Allergy . 2020   Jun ; all.14407 . 10.1111/all.14407 10.1111/all.14407...

...Mayumi Saeki; Tomoe Nishimura; Akio Mori; Takachika Hiroi Allergen-specific immunotherapy (IT) has been shown to provide clinical benefit for patients with allergic diseases. At present, subcutaneous and sublingual ITs are mainly authorized for clinical treatment. Oral administration of allergens...

.... The detection limit was 0.79 pg/ml. All assays were performed in duplicate. The primary outcome measures of the clinical study were any allergic disease (eczema, food allergy, allergic rhinitis or asthma) and atopic (IgE-associated) allergic disease cumulatively until 2 and 5 years. Secondary outcomes...

...S.Y. Lee; J.W. Kwon; J.H. Seo; Y.H. Song; B.J. Kim; J. Yu; K.S. Park; H. Kim; E.J. Kim; J.S. Lee; S.J. Hong Background: The results of recent studies suggest that factors in rural environments may protect against the development of allergic diseases, but the underlying mechanisms are not well...

...Urpu Sandini; Anna Kaarina Kukkonen; Tuija Poussa; Lorenzo Sandini; Erkki Savilahti; Mikael Kuitunen Background: Environmental and lifestyle factors such as breast-feeding and pets seem to affect atopic disease prevalence. We identified risk factors for allergic diseases. Methods: We prospectively...

...Ho-Chang Kuo; Chieh-An Liu; Chia-Yu Ou; Te-Yao Hsu; Chih-Lu Wang; Hsin-Chun Huang; Hau Chuang; Hsiu-Mei Liang; Kuender D. Yang Background: Exposure to cow’s milk protein in early infancy could lead to increased rates of allergic diseases later in life. We investigated whether feeding a protein...

...% of a group of subjects who were skin test positive to HDE and WME, but who reported no clinical history of allergic disease upon natural exposure to house dust, reacted to r Der p II. These results demonstrate the biological activity of r Der p II, and indicate, in persons skin test positive to house-dust...

...Ganesa Wegienka; Suzanne Havstad; Leo Shue; Edward Zoratti; Dennis R. Ownby; Christine Cole Johnson Background: Studies have shown an inverse association between birth order and allergic disease risk; some but not all have shown an inverse association between cord blood immunoglobulin E (IgE...

... reported that the polymorphism of the STAT6 gene exon 1 was associated with allergic diseases, while another group studied the G2964A variant of the STAT6 gene’s association with atopic asthma. We undertook an association study between these variants of the STAT6 gene and allergic diseases, including...