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1-7 of 7
Keywords: 5-Lipoxygenase
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Journal Articles
From Slow-Reacting Substance of Anaphylaxis to Leukotriene C 4 Synthase
Available to PurchaseSubject Area:
Immunology and Allergy
Int Arch Allergy Immunol (1995) 107 (1-3): 19–24.
Published Online: 04 September 2009
...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 5-Lipoxygenase Cysteinyl leukotrienes Eosinophils Mast cells The Paul Kallös Memorial Lecture lnt Arch Allergy...
Journal Articles
Inhibition of Leukotriene Synthesis by Honokiol in Rat Basophilic Leukemia Cells
Available to PurchaseSubject Area:
Immunology and Allergy
Yuhei Hamasaki, Eriko Muro, Shafigeh Miyanji, Shuichi Yamamoto, Ikuko Kobayashi, Rika Sato, Masafumi Zaitu, Muneaki Matsuo, Tomohiro Ichimaru, Hakaru Tasaki, Sumio Miyazaki
Int Arch Allergy Immunol (1996) 110 (3): 278–281.
Published Online: 04 September 2009
.... These results indicate that honokiol blocks LT synhesis by inhibiting 5-lipoxygenase activity. Honokiol also inhibited immunoglobulin E-mediated production of these LTs in RBL-2H3 cells, which was measured by a specific radioimmunoassay (RIA). These results suggest that honokiol may exhibit antiallergic actions...
Journal Articles
Treatment of Chronic Stable Asthma with Drugs Active on the 5-Lipoxygenase Pathway
Available to PurchaseSubject Area:
Immunology and Allergy
Int Arch Allergy Immunol (1995) 107 (1-3): 319–320.
Published Online: 04 September 2009
...Jeffrey M. Drazen; Elliot Israel It is now established that 5-lipoxygenase products are synthesized and released in the airway during asthmatic reactions. The importance of these products in the asthmatic response has been established through study of the effects of 5-lipoxygenase inhibitors...
Journal Articles
Role of Cyclooxygenase and 5-Lipoxygenase Metabolites, Platelet-Activating Factor and 5-Hydroxytryptamine in Allergen-Induced Airway Responses in the Brown Norway Rat
Available to PurchaseSubject Area:
Immunology and Allergy
Int Arch Allergy Immunol (1994) 103 (1): 67–72.
Published Online: 03 September 2009
...Wayne Elwood; Tatsuo Sakamoto; Peter J. Barnes; Fan Chung We determined the effects of selective inhibition of arachidonic acid metabolism via the cyclooxygenase and 5′-lipoxygenase pathways using flurbiprofen and BWA4C, respectively, of 5-hydroxytryptamine (5-HT) using methysergide and of platelet...
Journal Articles
Effect of Ibudilast, a Novel Antiasthmatic Agent, on Anaphylactic Bronchoconstriction: Predominant Involvement of Endogenous Slow Reacting Substance of Anaphylaxis
Available to PurchaseSubject Area:
Immunology and Allergy
Int Arch Allergy Immunol (1993) 101 (3): 288–296.
Published Online: 03 September 2009
... substance of anaphylaxis (SRS-A) from guinea pig chopped lung sensitized with OA, which was significantly diminished by indomethacin. The drug little affected the activity of phospholipase A 2 and 5-lipoxygenase in guinea pig polymorphonuclear leukocytes. These results indicate that ibudilast inhibits...
Journal Articles
Arachidonate 5-Lipoxygenase Metabolism in Human Neutrophils from Patients with Asthma: In vitro Effect of Nedocromil Sodium
Available to PurchaseSubject Area:
Immunology and Allergy
Int Arch Allergy Immunol (1992) 97 (3): 209–215.
Published Online: 02 September 2009
... in particular. In asthmatic patients (AP) with attacks, the capacity of blood PMN to produce 5-lipoxygenase metabolites was investigated and compared to the response in healthy subjects (HS). PMN from 6 AP and from 6 HS were stimulated by calcium ionophore A23187 and arachidonate 5-lipoxygenase metabolites were...
Journal Articles
The Effect of Leukotriene D 4 Inhalation on the Antigen-Induced Airway Hyperresponsiveness and Inflammation in 5-Lipoxygenase Gene-Deficient Mice
Available to PurchaseSubject Area:
Immunology and Allergy
Naoki Kawada, Takatoshi Yamada, Yoshimasa Takahashi, Shouta Tokuoka, Taisei Masuda, Hiroyuki Tanaka, Hiroichi Nagai
Int Arch Allergy Immunol (2001) 126 (4): 309–317.
Published Online: 23 January 2002
...Naoki Kawada; Takatoshi Yamada; Yoshimasa Takahashi; Shouta Tokuoka; Taisei Masuda; Hiroyuki Tanaka; Hiroichi Nagai Background: The role of 5-lipoxygenase (5-LO) products in the asthmatic bronchoconstriction is evident. However, the role of 5-LO products in airway hyperresponsiveness (AHR...
