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Keywords: α-Galactosylceramide
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Journal Articles
Subject Area:
Immunology and Allergy
Ryosuke Murakami, Yohko Nakagawa, Masumi Shimizu, Ayako Wakabayashi, Yasuyuki Negishi, Takachika Hiroi, Kimihiro Okubo, Hidemi Takahashi
Int Arch Allergy Immunol (2016) 168 (4): 219–232.
Published Online: 09 February 2016
... establish Th2 dominancy. Th1 polarization can be achieved either by depletion of 33D1+ DCs with a 33D1-specific monoclonal antibody (mAb) or by activation of DEC-205+ DCs via intraperitoneal injection of α-galactosylceramide (α-GalCer). We studied the effect of 33D1+ DC depletion or DEC-205+ DC activation...
Journal Articles
Subject Area:
Immunology and Allergy
Bastiaan Schouten, Betty C.A.M. van Esch, Stephanie M. Lim, Gerard A. Hofman, Léon M.J. Knippels, Linette E.M. Willemsen, Arjan P. Vos, Johan Garssen
Int Arch Allergy Immunol (2012) 159 (1): 51–59.
Published Online: 03 May 2012
... for cow’s milk allergy the function of iNKT cells was investigated. Methods: Mice were sensitized orally with casein or whey proteins. One hour before the sensitizations the mice were injected intraperitoneally with α-galactosylceramide (αGalCer) or control. One week after the last sensitization acute...
Journal Articles
Subject Area:
Immunology and Allergy
Toshinori Nakayama, Masakatsu Yamashita, Tetsu Kawano, Chiori Shimizu, Youichi Shibata, Tohru Kamata, Yoshikatsu Kaneko, Seiichiro Kobayashi, Ushio Takeda, Shinichiro Motohashi, Junqing Cui, Masaru Taniguchi
Int Arch Allergy Immunol (2001) 124 (1-3): 38–42.
Published Online: 24 January 2012
... stimulation with a ligand, α-galactosylceramide (α-GalCer), and play a crucial role in various immune responses, including allergic diseases. Interestingly, Vα14 NKT cells are not essential for the induction of IgE responses but rather induce suppression of specific IgE production upon activation...
