1.
Ohashi-Doi K, Kito H, Du W, Nakazawa H, Ipsen H, Gudmann P, et al: Bioavailability of house dust mite allergens in sublingual allergy tablets is highly dependent on the formulation. Int Arch Allergy Immunol 2017; 174: 26–34.
2.
Canonica GW, Cox L, Pawankar R, Baena-Cagnani CE, Blaiss M, Bonini S, et al: Sublingual immunotherapy: World Allergy Organization position paper 2013 update. World Allergy Organ J 2014; 7: 6.
3.
Moingeon P: Update on immune mechanisms associated with sublingual immunotherapy: practical implications for the clinician. J Allergy Clin Immunol Pract 2013; 1: 228–241.
4.
Akdis M, Akdis CA: Mechanisms of allergen-specific immunotherapy: multiple suppressor factors at work in immune tolerance to allergens. J Allergy Clin Immunol 2014; 133: 621–631.
5.
Mascarell L, Rak S, Worm M, Melac M, Soulie S, Lescaille G, et al: Characterization of oral immune cells in birch pollen-allergic patients: impact of the oral allergy syndrome and sublingual allergen immunotherapy on antigen-presenting cells. Allergy 2015; 70: 408–419.
6.
Actair® product information. Sydney, Stallergenes, 2016.
7.
Product outline of Actair®. Tokyo, Shionogi, 2015.
8.
Bergmann KC, Demoly P, Worm M, Fokkens WJ, Carrillo T, Tabar AI, et al: Efficacy and safety of sublingual tablets of house dust mite allergen extracts in adults with allergic rhinitis. J Allergy Clin Immunol 2014; 133: 1608–1614.
9.
Okamoto Y, Fujieda S, Okano M, Yoshida Y, Kakudo S, Masuyama K: House dust mite sublingual tablet is effective and safe in patients with allergic rhinitis. Allergy 2016; 72: 435–443.
10.
Demoly P, Emminger W, Rehm D, Backer V, Tommerup L, Kleine-Tebbe J: Effective treatment of house dust mite-induced allergic rhinitis with 2 doses of the SQ HDM SLIT-tablet: results from a randomized, double-blind, placebo-controlled phase III trial. J Allergy Clin Immunol 2016; 137: 444–451.
11.
Okubo K, Masuyama K, Imai T, Okamiya K, Stage BS, Seitzberg D, et al: Efficacy and safety of the SQ house dust mite sublingual immunotherapy tablet in Japanese adults and adolescents with house dust mite-induced allergic rhinitis. J Allergy Clin Immunol 2017; 139: 1840–1848.
12.
Note for guidance on the investigation of bioavailability and bioequivalence, 2000. EMEA/CPMP/EWP/1401/98.
13.
Jagr M, Eckhardt A, Pataridis S, Broukal Z, Duskova J, Miksik I: Proteomics of human teeth and saliva. Physiol Res 2014; 63(suppl 1):S141–S154.
14.
Allam JP, Wurtzen PA, Reinartz M, Winter J, Vrtala S, Chen KW, et al: Phl p 5 resorption in human oral mucosa leads to dose-dependent and time-dependent allergen binding by oral mucosal Langerhans cells, attenuates their maturation, and enhances their migratory and TGF-beta1 and IL-10-producing properties. J Allergy Clin Immunol 2010; 126: 638–645.
© 2018 S. Karger AG, Basel
2018
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the...
© 2018 S. Karger AG, Basel
2018
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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